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  • 2000-2004  (3)
  • 1980-1984  (4)
  • 1
    Electronic Resource
    Electronic Resource
    A comparison of the multi-test with the prick test and multi-test 2 (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 13 (1983), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Allergy skin testing of infants and small children continues to be time-consuming and nerve-wracking. We hoped to have found the solution to these problems by using the multi-test (MT). The latter consists of an applicator with 8 heads, each head consisting of nine plastic needles on which the allergen solution rests. Thus eight allergens can be tested simultaneously. During routine control skin testing we compared MT with our usual method, the prick test (PT), amongst twenty patients. Twenty-seven percent of the skin reactions differed by more than 1 +. When we compared PT results with the previous PT, the correlation of 16% was better despite several years interval between tests, different persons carrying out the tests, and hyposensitization of patients. We adapted the MT system and produced a model, multi-test 2 (MT-2), which consists of eight sterile disposable needles on a stainless steel base. When we compared the MT-2 with PT, only 6% differed by more than 1 +. Thus the MT-2 proves to be a useful alternative to the PT for those children, in whom the PT is too difficult to carry out.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1983.tb02623.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The simplified oscillation method for measuring nasal resistance during provocation with allergens (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 11 (1981), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The simplified oscillation method was adapted to register nasal resistance because complicated and difficult procedures limited other known rhinomanometric tests. An initial study of thirty-nine subjects compared the effect of different-sized masks, revealing that the smaller the face mask, the smaller the capacitance and the higher the effective resistance. After an initial measurement, a second study group of twenty healthy and twenty pollinosis patients aged from 4 to 40 years underwent nasal provocation with grass pollen extract. Both study groups showed that despite high resistance, reactances were minor. This occurs because the nose acts as an aperture and an aperture has minimal reactances. With increasing concentrations of pollen extract, the nasal resistance of pollinosis subjects increased steadily, whereas the controls showed no change. Passive anterior rhinomanometry was measured for comparison and results contrasted sharply with the oscillation method: prior to provocation, initial values of control and pollinosis groups were already significantly different; after provocation, there was a statistically significant rise in resistance amongst the control as well as the pollinosis subjects. Further, the oscillation method for measuring nasal resistance proved to be simple, effective, and suitable for children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1981.tb01609.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Formation of overwintering structures of Uncinula necator and colonization of grapevine under field conditions (2002)
    Oxford, UK : Blackwell Science Ltd
    Plant pathology 51 (2002), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Developing shoots of grapevine (Vitis vinifera cv. Kerner) were inoculated with conidia of the powdery mildew, Uncinula necator, at well-defined phenological stages of the host to provoke the development of flag shoots in the field and to investigate these shoots as early as possible in the following growing season for the presence of the pathogen. The disease progress was monitored and fungal growth and development on samples from a field trial were analysed by means of low-temperature scanning electron microscopy (LT–SEM). Mycelium was detected on the surface and in the interior parts of buds. The suitability of the field plot to analyse flag shoots was proven by the occurrence of such shoots in the following spring. Furthermore, early stages of cleistothecia development on berries were described for the first time. Establishment of U. necator in dormant buds of grapevine, giving rise to flag shoots in the following spring, is considered to play a significant role in overwintering of the pathogen in the vineyards of southern Germany.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3059.2002.00694.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Electron transfer in low energetic Ne2+/Ar, Kr collisions (1984)
    Springer
    The European physical journal 317 (1984), S. 139-143 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Single electron capture processes in Ne2+/Ar, Kr collisions were studied by aid of the high-resolution translational spectroscopy. At low collision energies (〈1 keV) the dominant contribution to the Ne+-spectrum arises from Ne2+ ions in the metastable1 S 0-state, although it is the weakest component of the primary Ne2+ beam. Ne2+(3 P) and Ne2+*(1 D) projectiles play no important role due to unfavourable energy defects. Target excitation processes as well as transfer ionisation are considered as a possible explanation for different structures in the measured Ne+ spectra.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01421247
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Aminodipeptidase inhibitor-induced cell death in quiescent lymphocytes: A review (2000)
    Springer
    Apoptosis 5 (2000), S. 319-322 
    Details
    ISSN: 1573-675X
    Keywords: aminodipeptidase ; caspase ; quiescence ; quiescent cell proline dipeptidase ; proteasome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We recently isolated and cloned an intracellular post-proline cleaving aminodipeptidase, quiescent cell proline dipeptidase (QPP), which has a substrate specificity very similar to that of dipeptidyl peptidase IV (CD26/DPPIV). Highly specific inhibitors of proline aminodipeptidases activate a novel apoptotic pathway in quiescent lymphocytes. The target of these inhibitors is not CD26/DPPIV, but appears to be QPP. The apoptosis pathway induced by the aminodipeptidase inhibitors is unusual in that it is restricted to quiescent lymphocytes, but not activated or transformed lymphocytes. The caspases activated in this apoptotic pathway are different from those activated in Fas or gamma-irradiation mediated cell death pathways, and furthermore, the proteasome appears to play a role in this death pathway. A large number of signal molecules including chemokines and cytokines have a highly conserved X-Pro motif on the N-terminus, rendering them potential substrates of QPP and players in the survival of resting lymphocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009675223443
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Electron capture by slow multiply charged Ar and Ne ions from atomic hydrogen (1981)
    Springer
    The European physical journal 299 (1981), S. 307-309 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract At collision energies below 15 keV total charge transfer cross sections have been measured for multiply charged Arζ+(2≦ζ≦6) and Neζ+(2≦ζ≦4) ions colliding with atomic hydrogen. A Wood discharge was used to provide a hydrogen target with a sufficiently high degree of dissociation. Results are compared with measurements performed at higher energies and with theoretical calculations. For ζ=2 cross sections in atomic hydrogen are much smaller than in the molecular case, for ζ〉2 the ratio of these cross sections varies between 0.7 and 1.6.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01441273
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Power-law decay of collisionally excited amino acids and quenching by radiative cooling (2003)
    Springer
    The European physical journal 25 (2003), S. 139-148 
    Details
    ISSN: 1434-6079
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We have investigated the time dependence of the fragmentation of protonated amino acids stored at 22 keV in the electrostatic ring ELISA. The ions were produced in an electrospray source and after bunching in a quadrupole trap they were excited by collisions in a Ne gas. As in earlier studies of metal clusters and fullerenes produced in “hot” ion sources we find that the dissociation of metastable molecules follows approximately a 1/t decay law until a time $\tau$ after which the yield falls off much more rapidly. We interpret this reduction as a result of radiative cooling with a characteristic cooling time, $\tau_c \simeq G\tau$ , where G is the magnitude of the exponent in an Arrhenius expression for the rate of the dominant fragmentation process. The values of $\tau$ obtained from fits to the data are in the range 9-17 ms corresponding to cooling times of a few hundred milliseconds, in good accord with the expected rate of cooling by emission from IR-active vibrations. The power-law behaviour for $t 〈 \tau$ varies somewhat between the different amino acids, with powers between -0.9 and -1.1. We argue that this may be due to a competition between fragmentation channels with different Arrhenius parameters.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjd/e2003-00093-9
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    Paper (German National Licenses)
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