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  • 1
    Electronic Resource
    Electronic Resource
    Protein-predominant meals inhibit the development of gastric tachyarrhythmia, nausea and the symptoms of motion sickness (2004)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 19 (2004), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Meal ingestion has been suggested to reduce susceptibility to the development of gastric tachyarrhythmia, the abnormal activity of the stomach that frequently accompanies nausea.Aim : To determine the types of meal that are most effective in preventing the development of gastric tachyarrhythmia, nausea and the symptoms of motion sickness provoked by a rotating optokinetic drum.Method : Participants received a carbohydrate beverage, a protein-predominant beverage or nothing immediately before exposure to the rotating drum. Subjective symptoms of motion sickness and electrogastrograms were collected during a 6-min baseline period and a subsequent 16-min drum rotation period.Results : Subjective symptoms of motion sickness scores were significantly more severe during the no-meal condition than during either the protein or carbohydrate condition. Central, peripheral and, to some extent, gastrointestinal symptoms were more severe during the carbohydrate condition than during the protein condition. Gastric tachyarrhythmia increased significantly less from baseline to drum rotation during both the protein and carbohydrate conditions than during the no-meal condition.Conclusions : Liquid protein-predominant meals were most effective in suppressing both the development of gastric tachyarrhythmia and the entire spectrum of motion sickness symptoms, including nausea.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2004.01885.x
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  • 2
    Electronic Resource
    Electronic Resource
    Fibrous proteins of normal and abnormal human epidermis (1979)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 100 (1979), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Keratin proteins of human epidermis have been isolated from normal and abnormal tissues. The normal proteins whether removed from living layers (prekeratin) or from the stratum corneum (keratin) are shown to consist of three chains, molecular weights 65,000 (A), 60,000 (B) and 52,000 (C). When compared with the epidermal proteins isolated from abnormal tissues, differences can be detected in the electrophoretic pattern of the subunits. In general, relative amounts of the individual chains are altered and in specific cases one or two of the polypeptides found normally are missing. All the α-fibrous proteins extracted are found to be very similar in amino acid composition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1979.tb01640.x
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  • 3
    Electronic Resource
    Electronic Resource
    Antibody-based diagnostic for ‘refractory’ periodontitis (2002)
    Oxford, UK : Munksgaard International Publishers
    Journal of clinical periodontology 29 (2002), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective: About 10–15% of US adults are ‘refractory’ to therapy for chronic periodontitis. Recently, studies suggest that these patients have elevated lysine decarboxylase activity in the sulcular microbiota. The aim of this study was to determine whether an elevated IgG antibody response to lysine decarboxylase, alone or with antibody to other bacterial antigens and baseline clinical measurements, would predict ‘refractory’ patients with high accuracy.Methods: Chronic periodontitis patients were treated using scaling and root planing (SRP) followed by maintenance SRP and 3-monthly re-examinations. If there was a loss of mean full mouth attachment or more than three sites appeared with 〉 2.5 mm new loss within a year, the subjects were re-treated (modified Widman flap surgery and systemically administered tetracycline). If attachment loss as above recurred, the subjects were ‘refractory’. Baseline clinical measurements and specific antibody responses were used in a logistic regression model to predict ‘refractory’ subjects.Results: Antibody to a peptide portion of lysine decarboxylase (HKL-Ab) and baseline bleeding on probing (BOP) prevalence measurements predicted attachment loss 3 months after initial therapy [pIAL = loss (0) or gain (1)]. IgG antibody contents to a purified antigen from Actinomyces spp. (A-Ab) and streptococcal d-alanyl glycerol lipoteichoic acid (S-Ab) were related in ‘refractory’ patients (R2 = 0.37, p 〈 0.01). From the regression equation, the relationship between the antibodies was defined as linear (pLA/S-Ab = 0) or non-linear pLA/S-Ab = 1). Using pLA/S-Ab, pIAL and age, a logistic regression equation was derived from 48 of the patients. Of 59 subjects, 37 had 2–4 mm attachment loss and were assigned as ‘refractory’ or successfully treated with 86% accuracy.Conclusion: HKL-Ab facilitated an accurate prediction of therapeutic outcome in subjects with moderate periodontitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-051X.2002.291009.x
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  • 4
    Electronic Resource
    Electronic Resource
    Precursor keratin protein from human epidermis (1978)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 98 (1978), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Prekeratin has been isolated from human epidermis using the method of Matoltsy for bovine nose epidermis. Analysis by sedimentation equilibrium indicates that human prekeratin is heterogeneous in solution. The molecular weight range is from about 200 × 103 to at least 2 × 106. Polyacrylamide gel electrophoresis shows three polypeptide chains of molecular weights 65,000, 60,000 and 58,000. A lower than average ratio of polar/apolar amino acid residues suggests that hydrophobic interactions are important for stability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1978.tb01618.x
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  • 5
    Electronic Resource
    Electronic Resource
    The role of histidine in human epidermis (1977)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 97 (1977), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Incorporation of radioactively-labelled histidine into half-thickness skin and into the major protein fraction extracted from epidermis by urea (protein Fraction A) has been measured and compared with the amount of labelled urocanic acid appearing in the same specimen.After a short lag period, incorporation into half-thickness skin and into protein Fraction A was foxmd to be linear up to 23 h of the study.Histidine appeared to be initially preferentially deaminated to urocanic acid. The somewhat erratic presence of urocanic acid at later periods is attributed to its high instability and solubility.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1977.tb14246.x
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  • 6
    Electronic Resource
    Electronic Resource
    Value of barium studies for predicting primary versus secondary non-Hodgkin's gastrointestinal lymphoma (2000)
    Springer
    Abdominal imaging 25 (2000), S. 368-372 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Gastrointestinal lymphoma—Non-Hodgkin's gastrointestinal lymphoma—Barium studies.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: To determine the predictive value of a single lesion versus multifocal disease for differentiating primary and secondary gastrointestinal (GI) lymphoma on barium studies. Methods: Our study group consisted of 90 cases of non-Hodgkin's GI lymphoma from the radiologic archives of the Armed Forces Institute of Pathology in which barium studies had been performed. Each of those studies was reviewed jointly by two of the authors to determine in a blinded fashion whether the patients had a single lesion or multifocal disease (defined as two or more discrete lesions). Medical and pathologic records were then reviewed to determine whether these patients had primary (defined as lymphoma arising in the GI tract) or secondary (defined as disseminated lymphoma with associated GI tract involvement) GI lymphoma. The final clinical diagnosis was then correlated with the radiographic findings to test the hypothesis that a single lesion is more likely to be associated with primary GI lymphoma and that multifocal disease is more likely to be associated with secondary GI lymphoma. Results: Sixty-eight patients had a single lesion in the GI tract on barium studies; 52 (76%) of these patients had primary GI lymphoma and 16 (24%) had secondary GI lymphoma. Another 22 patients had multifocal disease on barium studies; 20 (91%) of these patients had secondary GI lymphoma and two (9%) had primary GI lymphoma. Conclusion: The predictive value of a single lesion for primary GI lymphoma on barium studies was 76%, and the predictive value of multifocal disease for secondary GI lymphoma was 91%. Thus, our data suggest that it is often possible to differentiate these two forms of GI lymphoma on the basis of the radiographic findings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/s002610000055
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  • 7
    Electronic Resource
    Electronic Resource
    A test of the equivalence principle using a space-borne clock (1979)
    Springer
    General relativity and gravitation 10 (1979), S. 181-204 
    Details
    ISSN: 1572-9532
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract An experimental verification of Einstein's equivalence principle has been made using an atomic hydrogen maser in a space probe attaining an altitude of 10,000 km above the earth's surface. At the present stage of the data reduction, confirmation is at the 2×10−4 level of accuracy. The experiment and the resulting data are described including a comment on the limits to the anisotropy of the velocity of light. We believe that this is the first direct, high-accuracy test of the symmetry of the propagation of light and a beginning in the use of high-accuracy clocks in space to measure relativistic phenomena.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00759854
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  • 8
    Electronic Resource
    Electronic Resource
    Some sensory and motor factors influencing the control and appreciation of eye and limb position (1979)
    Springer
    Experimental brain research 36 (1979), S. 275-283 
    Details
    ISSN: 1432-1106
    Keywords: Spatial orientation ; Visual direction ; Motor control ; Tonic vibration reflex ; Myesthetic illusions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Some aspects of the manner in which the central nervous system uses sensory information for the guidance of eye and arm movements were investigated. When subjects experience apparent motion of their restrained forearm, induced by vibration of their biceps muscle in the dark, they are able to pursue with their eyes at least part of this “motion” and to point with their nonvibrated limb to the apparent location of the vibrated arm. The presence of a small target light on the vibrated hand limits the extent of illusory change in limb position and results in illusory motion of the target light in the same direction as the arm motion. When asked to indicate the spatial position of the light or hand, subjects still point with their nonvibrated arm to the apparent locations. Although visual pursuit of the illusory motion of the forearm can still be elicited in the presence of the target light on the hand, the subjects' eyes remain steadily fixating the stationary target light when they are instructed to track its illusory motion. These findings demonstrate that sensory and motor factors affecting the perception of visual direction and the guidance of arm and eye movements can be differentially employed at several levels of central nervous control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238911
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  • 9
    Electronic Resource
    Electronic Resource
    Nachweis und Bestimmung des Nitrat-Ions (1933)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 91 (1933), S. 213-214 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01331463
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