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  • 1
    Electronic Resource
    Electronic Resource
    A plan for on-line production and acceleration of radioactive isotope beams by use of electron cyclotron resonance ion source NANOGAN : The 8th international conference on ion sources (2000)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 71 (2000), S. 777-779 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: For the precise low background experiments on β decay and material sciences, we are planning to build a new ISOL-type facility to accelerate various β-radioactive nuclei utilizing the existing 5 MV Van de Graaff accelerator and an RFQ linac. Present status of the designing work is reported. In the present work, optical elements of the 41-m-long beam transport line to connect Van de Graaff accelerator and an RFQ linac were designed. Using two dipole magnets, two electric quadrupole doublets and six electric quadrupole triplets, low energy radioactive nuclear beams can be transported with sufficient efficiency. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1150291
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  • 2
    Electronic Resource
    Electronic Resource
    Dentoalveolar reconstruction of a missing premaxilla using bone graft and endosteal implants (2003)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 30 (2003), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  We report here on a patient with bilateral cleft lip and palate (BCLP) and a missing premaxilla, who underwent dentoalveolar reconstruction of the cleft and premaxillary alveolus using endosteal implants after bone grafting. The patient, whose maxillary incisors and premaxilla were missing, had corticocancellous bone grafting from the iliac crest, followed by excellent bone formation at the anterior alveolus. After the placement of the endosteal implants and the completion of the pre-surgical orthodontic alignment, orthognathic surgery was performed for the restoration of a Class III open bite. After post-operative orthodontic preparation, the final fixed prostheses were completed. This treatment procedure offers an option of dentoalveolar reconstruction for BCLP patients with an excised premaxilla.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2003.00999.x
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  • 3
    Electronic Resource
    Electronic Resource
    Dental rehabilitation using endosseous implants and orthognathic surgery in patients with cleft lip and palate: report of two cases (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We describe the use of endosseous implants in the autogenous particulate cancellous bone and marrow grafted alveoli after orthognathic surgery for dental rehabilitation of patients with cleft lip and palate. This procedure has been applied to two patients and produced good results functionally and aesthetically. The results are encouraging and indicate that implant placement after orthognathic surgery is useful for patients both with congenital missing teeth and retrognathic maxillae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2000.00539.x
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  • 4
    Electronic Resource
    Electronic Resource
    A time pickup system for monitoring cyclotron beam bursts (2002)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 73 (2002), S. 51-55 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have developed a time pickup system for monitoring the beam bursts from a cyclotron. The time pickup can measure the phase and the width of the beam bursts by detecting secondary electrons emitted from a foil or a wire target inserted into the beam with time resolutions around 200 ps full width at half maximum in spite of its simple structure. By using the foil and the wire targets appropriately, monitoring the bursts of a variety of beams can be achieved. In addition, by adjusting the position of the target, a high enough detection rate of the beam burst is obtained with a minimum of interference with the beam. The present investigation shows that it is needed to adjust the collection voltage of the time pickup because the optimum collection voltages for high resolution measurement are in the range from −0.5 to −1.0 kV and those for high efficiency measurement are not less than −4.0 kV. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1416116
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  • 5
    Electronic Resource
    Electronic Resource
    Studies on the binding mechanism of fluoroquinolones to melanin (2000)
    Springer
    Journal of infection and chemotherapy 6 (2000), S. 72-76 
    Details
    ISSN: 1437-7780
    Keywords: Key words Ocular melanin ; Melanin affinity ; Fluoroquinolones ; Metal ions ; Binding mechanism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to elucidate the binding mechanism of melanin and fluoroquinolones (ofloxacin, norfloxacin, ciprofloxacin, lomefloxacin, levofloxacin), we investigated the interaction of fluoroquinolones with compounds such as l-β-(3,4-dihydroxyphenyl) alanine (l-DOPA), l-tyrosine, 5-hydroxy-l-tryptophan, l-tryptophan, and l-phenylalanine, which possess the kind of functional groups that melanin does and are closely related to melanin. The recovery of drugs from the melanin-drug complexes by metal ions of Li, Na, Ka, Mg, Ca, Ba, Cu, Ni, and Fe was demonstrated. Smaller and highly charged cations were found to be more effective for this recovery, and magnesium ions were the most effective of all the ions investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00012154
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  • 6
    Electronic Resource
    Electronic Resource
    Ganglioglioma with a tanycytic ependymoma as the glial component (2000)
    Springer
    Acta neuropathologica 99 (2000), S. 310-316 
    Details
    ISSN: 1432-0533
    Keywords: Key words Ganglioglioma ; Ependymoma (tanycytic variant) ; Neurofibrillary tangle ; Immunohistochemistry ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied a cystic ganglioglioma (GG) located in the right frontal lobe of the brain. Interestingly, the fibrillary spindle glial cells were often arranged in a fascicular pattern, and the generally uniform, round-to-oval delicate nuclei appeared to resemble those of ependymoma; and the neoplastic neurons often contained neurofibrillary tangles (NFTs). The glial component was positive for glial fibrillary acidic protein and occasionally contained granular or microvesicular structures positive for epithelial membrane antigen. Ultrastructural investigation revealed that the glial cells were ependymal in nature; intracytoplasmic lumina and intercellular microrosettes lined with cilia and microvilli, as well as long zonulae adherentes, were evident. In addition, chromogranin A-positive granular staining, neurosecretory-granule-like structures, and parallel arrays of microtubules were sometimes associated with the blood vessels. We considered the present case to be an unusual example of GG with an ependymoma, more precisely a tanycytic ependymoma, as the glial component; to our knowledge, the existence of ependymoma as the main glial component of this particular tumor has not been described before. The occurrence of NFTs, which has been reported in several cases of GG, was an additional, unusual feature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00007443
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  • 7
    Electronic Resource
    Electronic Resource
    Toxic Assessment of PCBs by the 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Equivalent in Common Cormorant (Phalacrocorax carbo) from Japan (2000)
    Springer
    Archives of environmental contamination and toxicology 38 (2000), S. 509-521 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Common cormorants collected from three colonies and their fish diet were analyzed for PCB congeners and 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQs) were estimated. The highest total PCBs (40 μg/g wet weight) found in adult cormorants from Shinobazu Pond located in Central Tokyo, was sevenfold higher than that from Lake Biwa. IUPAC 153 was the most abundant congener in adults and eggs, whereas IUPAC 28 + 31 was higher in some chicks and exhibited growth-related congeneric enrichment. The estimated metabolic index (MI) for PCB congeners revealed that mono- and non-ortho coplanars had higher bioaccumulation in cormorant liver and were expected to cause toxic effects. Among non-ortho coplanars, IUPAC 126 was predominant, and total non-ortho coplanars and TEQs in cormorants were threefold higher in Shinobazu Pond than those from Lake Biwa. The non-ortho IUPAC 126 contributed a higher portion to the total TEQs followed by IUPAC 105 and IUPAC 77. The hepatic IUPAC 169/126 ratio increased significantly with TEQs, implying a potential induction of drug-metabolizing enzymes in Shinobazu Pond cormorants. Based on the available data, PCB contamination in cormorants is enough to pose sublethal effects, especially in Shinobazu Pond and Godaiba Island, Tokyo, Japan. This could be a reason for recently observed high chick and juvenile mortality in those colonies in Tokyo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002440010067
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  • 8
    Electronic Resource
    Electronic Resource
    Report of a patient with aortic dissection evolving into binocular ischemic retinopathy (2000)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 238 (2000), S. 200-202 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract · Background: Carotid artery disease is known to cause a variety of ischemic ocular syndromes. We report a patient with an aortic dissection that evolved into binocular ischemic retinopathy. · Methods: Case report.· Results: A 49-year-old male patient presented with stomach pains and with no ophthalmologic symptoms. After extensive examination, a diagnosis of aortic dissection was made to account for the acute abdominal pain. Sixteen days later, he noted binocular photopsia and ophthalmoscopy revealed ischemic retinopathy. Arterial stent implantation and right coronary reconstitution surgery were performed. Subsequently, the ischemic lesions in the retina disappeared and no abnormality was observed by retinal angiography 1 year later. · Conclusion: Binocular ischemic retinopathy can be a sign of aortic or carotid dissection, and these observations suggest that aortic dissection should be included in the differential diagnosis whenever ischemic changes are detected in the retina.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004170050033
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