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  • 1
    Electronic Resource
    Electronic Resource
    Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions (2001)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 144 (2001), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2001.04032.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Genetic modification of the fatty acid unsaturation of phosphatidylglycerol in chloroplasts alters the sensitivity of tobacco plants to cold stress (2004)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 27 (2004), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The cis-unsaturated molecular species of phosphatidylglycerol (PG) in chloroplasts have been implicated in the chilling sensitivity of plants. Homozygous lines of transgenic tobacco (Nicotiana tabacum) that overexpressed the cDNA for glycerol-3-phosphate acyltransferase, a key enzyme in the determination of the extent of cis-unsaturation of PG, were established from a chilling-sensitive squash (Cucurbita moschata). In transgenic plants, the proportion of saturated plus trans-monounsaturated molecular species of PG increased from 24 to 65%. However, this change did not affect the architecture of the chloroplasts. Chilling stress decreased the growth and biomass production of young seedlings of transgenic plants more severely than those of wild-type plants, and this observation suggests that the changes in the proportion of cis-unsaturated PG affected not only leaves but also developing plants. Chilling stress also damaged inflorescences. In particular, the abscission of flower buds and inflorescence meristems from transgenic plants occurred more frequently than that from wild-type plants. Thus, it is likely that decreases in the proportion of cis-unsaturated PG enhanced the sensitivity to chilling of reproductive organs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0016-8025.2003.01131.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The structure and dimensions of redds and egg pockets of the endangered salmonid, Sakhalin taimen (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 56 (2000), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Each redd of the Sakhalin taimen Hucho perryi had a V–shaped pot that is specific to this species. The shape of each multiple–egg–pocket redd was a combination of one–egg–pocket redds, and the number of egg pockets in the redd could be estimated from the shape. False redds were small and did not have any V–shaped pots. The factors affecting redd size were examined numerically; consequently, numbers of egg pockets and eggs and female fork length were correlated significantly with tail length. Each egg pocket contained 11–920 eggs (mean: 546·7±95% CL 81·9) and the egg pocket depth was correlated significantly with female fork length. Mean number of redds per female was three, and the number of females could be estimated as one third of the redds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.2000.tb00879.x
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  • 4
    Electronic Resource
    Electronic Resource
    Reproductive strategy in orphaned colonies of Myrmica kotokui Forel, the Japanese species of the M. ruginodis complex (Hymenoptera, Formicidae) (2000)
    Springer
    Insectes sociaux 47 (2000), S. 343-347 
    Details
    ISSN: 1420-9098
    Keywords: Key words:Monogyny, Myrmica ruginodis complex, orphaned colony, reproductive strategy, worker reproduction.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary: The reproductive strategy between queen-right and orphaned colonies of Myrmica kotokui was compared. The ratio of orphaned colonies reached about 30 percent in the field. Although colony size was significantly smaller in orphaned colonies, the mean body size and mean ovariole length of the workers were significantly larger than those in queen-right colonies. The reproductive individuals in orphaned colonies were also significantly larger than those in queen-right colonies. Only 38.5 % of the orphaned colonies, however, contained eggs during the reproductive season, compared to 100 % of the queen-right colonies. This indicates that worker reproduction under natural conditions is relatively low, even in orphaned colonies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00001727
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  • 5
    Electronic Resource
    Electronic Resource
    Augmented prostaglandin E2 generation resulting from increased activities of cytosolic and secretory phospholipase A2 and induction of cyclooxygenase-2 in interleukin-1β-stimulated rat calvarial cells during the mineralizing phase (2000)
    Springer
    Inflammation research 49 (2000), S. 102-111 
    Details
    ISSN: 1420-908X
    Keywords: Key words: Osteoblast — Prostaglandin E2— Primary culture — Phospholipase A2— Cyclooxygenase-2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Objective and Design: To assess prostaglandin (PG) E2 production by osteoblasts during the mineralizing phase after interleukin (IL)-1β stimulation, using an in vitro system of rat calvarial cells cultured for 21 days.¶Methods: The cells, which reached confluence after 3 days, were designated day 0 cells. Culture was continued for a further 21 days after confluence. The cells on the 21st day of the culture were designated day 21 cells.¶Results: The PGE2 concentration in the medium of the day 21 cells was increased 72 h after IL-1β treatment, and reached a peak level approximately 1,400 times that of the day 0 cells 6 h after IL-1β treatment. We examined the effects of IL-1β on PGE2 production and changes in the relevant enzyme activities, and found that the activities of cytosolic phospholipase A2 (cPLA2), type II secretory PLA2 (sPLA2) and cyclooxygenase (COX)-2 in the day 21 cells were increased. Both selective COX-2 inhibitor and cPLA2 inhibitor abolished PGE2 generation, whereas an sPLA2 inhibitor partially inhibited it. Taken together, these results indicate that COX-2 and cPLA2 play pivotal roles and sPLA2 is involved in IL-1β-stimulated PGE2 production by these cells. Furthermore, we found that IL-1β treatment induced PGE synthase activity and this correlated well with PGE2 production.¶Conclusion: Augmented PGE2 production by mineralizing osteoblasts after IL-1β treatment, and the involvement of IL-1β-induced cPLA2, sPLA2, COX-2 and PGE synthase activities in this phenomenon were demonstrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000110050566
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  • 6
    Electronic Resource
    Electronic Resource
    Food habits of Aenictus army ants and their effects on the ant community in a rain forest of Borneo (2000)
    Springer
    Insectes sociaux 47 (2000), S. 42-49 
    Details
    ISSN: 1420-9098
    Keywords: Key words:Aenictus, army ants, ant community, Borneo.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary: In a rain forest at the foot of Mt. Kinabalu, Borneo, we observed the food habits of Aenictus laeviceps and A. gracilis and surveyed the effects of A. laeviceps on the general ant community. We collected totals of 2,360 and 6,268 prey units, respectively, from seven A. laeviceps and six A. gracilis colonies; ants constituted 99.9% of all prey units. Dominant prey genera were Camponotus (48.2% in wet weight), Pseudolasius (20.8%), and Polyrhachis (15.2%) in A. laeviceps and Technomymex (52.1%), Paratrechina (22.4%), and Crematogaster (11.9%) in A. gracilis. A. laeviceps primarily hunted larger ground ants with small- or medium-sized colonies; in contrast, A. gracilis frequently foraged on smaller arboreal ants with larger colonies. Of the total wet weight of prey ants, brood constituted 88.7% in A. laeviceps and only 68.7% in A. gracilis. This was probably because workers of A. gracilis were quicker in behavior and hunted adult workers more frequently than A. laeviceps. While 98.5% of the prey units were transported by single workers of A. gracilis, 71.5% were carried by up to 20 A. laeviceps workers. The numbers of ant colonies and species were significantly smaller in laeviceps-raided quadrats than in controls. This was mostly due to the escape of ants that nested under litter and had relatively larger colonies. Large colonies usually influence the foundation and establishment of incipient small colonies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000400050007
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