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  • 1
    Electronic Resource
    Electronic Resource
    Time course of 8-MOP-induced skin photosensitization in PUVA bath photochemotherapy (1997)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 136 (1997), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1997.tb14978.x
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  • 2
    Electronic Resource
    Electronic Resource
    Muir-Torre syndrome: clinical features and molecular genetic analysis (1997)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 136 (1997), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a 62-year-old man with rectal cancer, two keratoacanthomas and multiple sebaceous adenomas, epitheliomas and sebaceous hyperplasia. His brother and father died from colorectal cancer. A subgroup of patients with the Muir-Torre syndrome (MTS) is allelic to the cancer family syndrome. This genetic disorder is caused by an autosomal dominant inherited germline mutation in one of the DNA mismatch repair genes. It is thought that a somatic mutation of the other allele leads to a genomic instability responsible for tumorigenesis. In the patient presented here the instability was detected in two characteristic skin lesions; sebaceous adenoma and epithelioma. The search for a causal germline mutation revealed a frameshift mutation in the mismatch repair gene hMSH2 leading to a truncated protein. A presymptomatic molecular diagnosis can be offered to the children of the patient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1997.01805.x
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  • 3
    Electronic Resource
    Electronic Resource
    Photo hen's egg test: a model for phototoxicity (1997)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 136 (1997), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this investigation was to establish a new model for phototoxicity which is more advanced than the widely used cultures of yeasts, bacteria or cells of various origin, and at the same time to avoid animal testing. We studied the extraembryonal vasculature of the incubated hen's egg. This model was originally introduced by toxicologists as an alternative to the rabbit's eye irritation test (Draize test). In the photo hen's egg test, substances are applied to the embryo's yolk-sac blood vessel system at a non-toxic concentration and are irradiated with 5 J/cm2 ultraviolet A (UVA) (320-400 nm). Promethazine, haematoporphyrin, ciprofloxacin and 8-methoxypsoralen were tested in this system. Death of the embryo, membrane discoloration and haemorrhage are parameters for phototoxic damage, which were recorded during an observation period of 24 h. These well-known phototoxic substances induced pronounced damage of the yolk-sac membrane and blood vessels which was not found in the controls (test substance alone, UVA alone or untreated) using a 2 × 2 factorial test design. The photo hen's egg test serves as a valid screening model for substances supposed to be photosensitizers owing to a phototoxic mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1997.d01-1193.x
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  • 4
    Electronic Resource
    Electronic Resource
    Topical calcipotriol in the treatment of intertriginous psoriasis (1996)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 135 (1996), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary The purpose of this study was to examine the effectiveness and side-effects of the vitamin D analogue calcipotriol, applied topically to psoriatic skin lesions in intertriginous areas, in an open and uncontrolled trial. Twelve patients with psoriasis vulgaris who presented with psoriatic lesions in the axilla, and inguinal and anal folds, were treated with calcipotriol ointment (50μg/g) twice daily for 6 weeks. Examination and photographic documentation were performed before treatment, at 3 weeks of treatment, and at 6 weeks of treatment. The mean improvement in the extent and severity of the psoriatic plaques was determined with a semiquantitative grading system closely realted to the psoriasis area and severity index (M-PASI). Two of 12 patients showed insufficient response to therapy. Five of 12 patients showed a quick response within 3 weeks or less, and five of 12 patients showed a slow response which could be seen only after 6 weeks of treatment. Minimal burning was reported in one patient, slight lesional and/or perilesional irritation in five patients, and, in the remaining, no side-effects occurred. Topical calcipotriol is an effective and safe treatment for intertriginous psoriasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1996.d01-1060.x
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  • 5
    Electronic Resource
    Electronic Resource
    PUVA therapy in disabling pansclerotic morphoea of children (1995)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 132 (1995), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1995.tb00738.x
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  • 6
    Electronic Resource
    Electronic Resource
    Eine colorimetrische Methode für die Bestimmung des Eisens im Wasser (1927)
    Springer
    European food research and technology 54 (1927), S. 374-376 
    Details
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01653779
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  • 7
    Electronic Resource
    Electronic Resource
    Modification of Interdendritic Convection by a Magnetic Field (1996)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 217-222 (May 1996), p. 235-240 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/01/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.217-222.235.pdf
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  • 8
    Electronic Resource
    Electronic Resource
    Periorbitales Ödem als Initialsymptom eines Lupus erythematodes profundus (1999)
    Springer
    Der Hautarzt 50 (1999), S. 889-892 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Kollagenose ; Lupus erythematodes profundus ; Periorbitales Ödem ; Key words Collagenosis ; Lupus panniculitis ; Periorbital edema
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Periorbital edema may occur initially or in the course of a wide variety of diseases. One of these diseases is lupus panniculitis, a variant of lupus erythematosus, characterized by firm subcutaneous nodules that may ulcerate with subsequent scar formation. We present a case of lupus panniculitis in which the periorbital edema was the initial manifestation. Knowledge about the differential diagnostic possibilities of periorbital edema as well as the different variants of cutaneous lupus erythematosus is important to reach the correct diagnosis.
    Notes: Zusammenfassung Das periorbitale Ödem ist ein Symptom, das initial oder im Verlauf von Erkrankungen verschiedenster Genese auftreten kann. Eine mögliche Assoziation stellt der Lupus erythematodes profundus dar. Diese Krankheit ist durch subkutane knotige und plattenartige Infiltrate gekennzeichnet, welche zu Ulzerationen und narbigen Einziehungen führen können. Anhand eines Fallberichts wird aufgezeigt, daß ein periorbitales Ödem als Initialsymptom den typischen Hautveränderungen eines Lupus erythematodes profundus vorausgehen kann. Die Kenntnis der möglichen Differentialdiagnosen bei periorbitalem Ödem sowie der unterschiedlichen Varianten eines Lupus erythematodes ist für die Diagnosestellung von entscheidender Bedeutung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050051005
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  • 9
    Electronic Resource
    Electronic Resource
    Skabies-getriggerter bullöser Lichen ruber planus im Kindesalter (1998)
    Springer
    Der Hautarzt 49 (1998), S. 929-931 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Bullöser Lichen ruber planus ; Kindesalter ; Skabies ; Köbner-Phänomen ; Key words Bullous Lichen ruber planus ; Childhood ; Scabies ; Köbner’s-phenomenon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Lichen ruber planus is considered a T-cell mediated immunologic reaction with unclear pathogenesis. Drugs and infections (especially hepatitis B and C) are well-known provocation factors. After an infection with scabies a 13 year old boy developed a generalized lichen planus including bullous lesions. For the first time scabies is presented as a trigger for lichen planus. In childhood, lichen planus is characterized by atypical clinical features and sometimes a severe course.
    Notes: Zusammenfassung Der Lichen ruber planus wird heute als T-Zell-vermittelte immunologische Reaktion angesehen, deren Pathogenese unklar ist. Neben Medikamenten sind auch Infektionen (insbesondere Hepatitis B und C) als Provokationsfaktoren bekannt. Bei dem hier vorgestellten Fall eines bullösen Lichen ruber planus im Kindesalter konnte erstmalig eine Skabiesinfektion als Triggerfaktor beobachtet werden. Der Lichen ruber planus des Kindesalters zeichnet sich durch atypische Erscheinungsformen aus mit z.T. schweren Verläufen unter Aussparung der Schleimhäute.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050850
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  • 10
    Electronic Resource
    Electronic Resource
    Stärkebestimmung (1927)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 71 (1927), S. 362-364 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01391300
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