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  • 1
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 137 (1997), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary We report three cases of acute generalized exanthematous pustulosis (AGEP) following oral administration of nystatin. All cases showed similar clinical features and hislopathological findings, and a delnyed-type hypersensitivily to nystatin could be demonstrated in patch and prick testing. Drug eruptions to nystatin are extremely rare, and, to our knowledge, AGEP has not been reported previously.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 137 (1997), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Type 2 helper T-cell immune responses can be demonstrated in the human atopic disorders atopic dermatitis and allergic asthma/rhinoconjunctivitis. The CD30 (Ki-1) antigen, originally described on Hodgkin and Reed-Sternberg cells, has recently been proposed as a marker of T cells with potent B-cell helper activity producing IL-5 and γ-IFN, as well as on CD4+ and CD8+ T cells with a Th2 cytokine profile. As a soluble form of CD30 (sCD30) is released by CD30+ cells in vivo, we studied its clinical significance in atopic disorders compared with allergic contact dermatitis and healthy controls. Elevated sCD30 levels were associated with atopic dermatitis (P 〈 0.0001), but not with respiratory atopic disorders or allergic contact dermatitis. sCD30 levels in patients with atopic dermatitis were independent of serum IgE. The particular occurrence of serum sCD30 in patients with atopic dermatitis indicates a special regulatory function of CD30+ cells in this disease.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 135 (1996), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 134 (1996), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a 24-year-old woman, her 6-year-old son and her 1 7-month -old daughter, who all suffer from a rare congenital genodermatosis first delineated by Huriez et al. in the 1960s. The clinical features of this autosomal dominant condition include scleroatrophy of the hands and feel, nail hypoplasia, mild palmoplantar keratoderma and hypohidrosis. Histological changes are non-specific, but immunohistological and ultrastructural examination in our index patient revealed an almost complete absence of epidermal Langerhans cells in the affected skin. This new finding may be linked to the cancer proneness of the scleroatrophic skin. In this family, the grandmother had died at the age of 37 years from metastatic squamous cell carcinoma which had arisen on the thenar eminence.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 21 (1996), S. 0 
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Temporal arteritis, a variant of giant cell arteritis, is a systemic granulomatous vasculitis of large and medium-sized arteries. Usually the clinical Features arc dominated by ophthalmological and neurological complications. In rare instances, ischaemic necrosis, especially of the scalp, may lead patients to the dermatologist. We report a 76-year-old woman presenting with a unilateral scalp necrosis, accompanied by a dramatic ipsilateral impairment of vision. Immediately after duplex-sonography of the extracranial vessels and after initiation of corticosteroid therapy, the diagnosis of temporal arteritis was confirmed by temporal art en biopsy. One month later, because of insufficient secondary healing of the ulcer, the defect was covered by a mesh graft. The taking of the graft was delayed due to immunosuppressive therapy, but was complete. The patient unfortunately died as a result of complications related to surgical removal of an aspergilloma in the sphenoid cavity secondary to immunosuppressive therapy. We discuss the technique of artery biopsy and the possibility of surgical management of scalp necrosis in temporal arteritis.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 48 (1997), S. 838-838 
    ISSN: 1432-1173
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Streifen- und wirbelförmige nävoide Hypermelanose ; Lineare pigmentierte Dermatosen ; Blaschko-Linien ; Mosaik ; Key words Linear and whorled nevoid hypermelanosis ; Linear pigmented dermatoses ; Lines of Blaschko ; Mosaicism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A 7 year old boy presented with linear and whorled nevoid hypermelanosis (LWNH). This entity, delineated in 1988, is characterized by streaked or whorled, frequently reticulate hyperpigmented lesions following the lines of Blaschko without preceding inflammation and without atrophy. The age of onset is usually within the first 2 years of life. Histologically, there is a mild basal cell hyperpigmentation with prominent melanocytes. In contrast to earlier reports, we observed some melanophages in the upper dermis. Associated abnormalities have been reported in a few patients, but were absent in our case. We present the clinical features, diagnostic criteria and differential diagnosis of this rare entity. Apparently, our patient represents the first case of LWNH in the German literature.
    Notes: Zusammenfassung Wir diagnostizierten bei einem 7jährigen Patienten eine streifen- und wirbelförmige nävoide Hypermelanose (SWNH). Die wesentlichen Kriterien dieser 1988 beschriebenen Entität sind lineare, oft retikuläre Hyperpigmentierungen entlang der Blaschko-Linien ohne entzündliches Vorstadium und ohne Atrophie der Läsionen. Die Erkrankung manifestiert sich meist innerhalb der ersten 2 Lebensjahre. Histologisch ist eine verstärkte Pigmentierung des Stratum basale mit prominenten Melanozyten zu finden. Im Gegensatz zu früheren Beobachtungen fanden sich bei unserem Patienten einige Melanophagen im oberen Korium im Sinne einer Pigmentinkontinenz. In wenigen Fällen wurden assoziierte Mißbildungen mitgeteilt, fanden sich im vorgestellten Fall jedoch nicht. Anhand dieses Fallberichtes möchten wir das klinische Bild, die diagnostischen Kriterien und die Differentialdiagnosen dieser seltenen Entität darstellen. Soweit uns bekannt, stellt unser Patient den ersten Fall einer SWNH in der deutschsprachigen Literatur dar.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 47 (1996), S. 638-641 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Genitale weiße Piedra ; Schambehaarung ; Trichosporon-Spezies ; Key words Genital white piedra ; pubic hair ; Trichosporon sp.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary White piedra is a rare hair infection of man and certain animals, caused by the widespread Trichosporon fungi. The infection is characterized clinically by whitish, soft and easily removable coating of the hair shafts; however, the shafts may be destroyed by the pathogens invading at localized points. While all body hair may be affected, the pubic hair is most frequently affected. This paper is the first report genital white piedra in a 34-year-old Central European man. In all, 22 cases have been described world-wide in young men ranging in age from 20 to 40 years. Only 2 men, aged 42 and 53 years, do not fall in this range. Recently, a major African study disclosed this disease in women for the first time. In moderate latitudes, however, this infection appears to occur almost exclusively in young men.
    Notes: Zusammenfassung Die weiße Piedra ist eine seltene Haarerkrankung des Menschen und bestimmter Tiere durch die weitverbreitete Hefe der Gattung Trichosporon. Klinisch ist die Infektion durch weißliche, weiche und leicht abstreifbare Beläge an den Haarschäften charakterisiert; an umschriebenen Stellen können die Schäfte jedoch auch durch Invasion der Erreger zerstört werden. Prinzipiell können alle Körperhaare befallen sein; mit 95% am weitaus häufigsten ist jedoch die Genitalbehaarung betroffen. Wir berichten hier zum ersten Mal über eine genitale Piedra alba bei einem 34jährigen Mann aus dem deutschsprachigen Raum. Weltweit wurden bisher 22 Fälle bei jungen Männern im 3. und 4. Lebensjahrzehnt beschrieben. Nur 2 Männer mit 42 respektive 53 Jahren fallen aus dieser Altersverteilung heraus. Kürzlich wurde erstmals in einer großen afrikanischen Studie über diese Erkrankung detailliert auch bei Frauen berichtet. In den gemäßigten Breiten scheint diese Erkrankung jedoch fast ausschließlich bei jungen Männern vorzukommen.
    Type of Medium: Electronic Resource
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