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  • 1
    Electronic Resource
    Electronic Resource
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 6 (1995), S. 0 
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Critical events in the adaptation of osseous tissues to implant materials involve initial calcification of the newly synthesized bone. Previous studies indicated that bone-bonding but not nonbonding glass ceramics increase the matrix vesicle number, thereby compensating for delayed maturation of the extracellular organelles. The present study assessed whether this was also true for metal implants commonly used in orthopaedics and oral medicine. Bone-bonding titanium (Ti) or nonbonding stainless steel (SS) implants were placed in the right tibias of Sabra rats following ablation of the marrow. At 3, 6, 14, and 21 days postinjury, newly formed endosteal bone in the treated and contralateral limbs was removed and matrix vesicle-enriched membranes isolated. Alkaline phosphatase and phospholipase A2 specific activities and phosphatidylserine (PS) content were determined and compared with those of a nonsurgical control group. Results show that matrix vesicle alkaline phosphatase and phospholipase A2 activity and PS content was increased in the Ti-implanted limbs at 6 (peak). 14, and 21 days, although at levels less than observed in normal ealing. Alkaline phosphatase activity remained elevated throughout the healing period. In contrast, these parameters were markedly inhibited in the SS-implanted limbs with respect to Ti or to normal healing. Both implants altered the systemic response associated with marrow ablation. but in an implant-specific manner. The results support the hypothesis that cells adjacent to bone-bonding materials can compensate for negative effects on primary mineralization during osteogenesis, whereas cells adjacent to nonbonding materials either do not compensate or are further depressed. The data support the use of the rat marrow ablation model as a tool for rapid, initial assessment of biomaterials in bone.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-4994
    Keywords: Natural organic matter ; humic substances ; time-resolved fluorescence ; distribution analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Time-resolved fluorescence measurements of aquatic natural organic matter (NOM) derived from different origins were performed using the time-correlated single-photon counting technique. The obtained experimental data were analyzed with nonlinear least-squares (NLLS) algorithms. The results of a global analysis with three exponential decay terms were compared with the results obtained in a distribution analysis (exponential series method; ESM). Fulvic acid fractions from a bog lake water, from a brown coal production effluent, and from a soil seepage water as well as NOM from a municipal waste water were investigated. The influence of the emission wavelength on the NOM fluorescence decay was monitored. Furthermore, the influence of fractionation using size exclusion chromatography, of ozonation, and of metal ion complexation on the fluorescence decay of the NOM samples was investigated.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 18 (1995), S. 753-756 
    ISSN: 0935-6304
    Keywords: Capillary gas chromatography ; Electronic flow controller ; Advanced flow controller (AFC) ; Pressure programming ; Flow programming ; Automatic optimization ; Split injection ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: An electronic gas-flow controller system called Advanced Flow Control (AFC), which controls not only carrier gas pressure at the column inlet but also the total gas flow including the split flow, was designed and evaluated. BASIC programming of repetitive analyses of standard mixtures under varied split ratios and pressure programs allowed automated optimization of those conditions for the desired column loading and resolution between adjacent peaks.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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