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  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 255-257 (Sept. 1997), p. 269-271 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experiments in fluids 20 (1995), S. 84-90 
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The paper presents the results of an investigation on the motion of a spherical particle in a shock tube flow. A shock tube facility was used for studying the acceleration of a sphere by an incident shock wave. Using different optical methods and performing experiments in two different shock tubes, the trajectory and velocity of a spherical particle were measured. Based upon these results and simple one-dimensional calculations, the drag coefficient of a sphere and shading effect of sphere interaction with a shock tube flow were studied.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  The paper describes new experimental results regarding the pressure fields in front of and inside granular layers of different materials during their collision with weak shock waves. A variety of waves result from the shock wave-granular layer interaction. The pressure behind the reflected wave from the material interface approaches the equilibrium value, P 5, which would have been reached had the shock wave reflected from a solid end-wall. The wave succession inside the layer depends solely on two processes: the complex interaction of the compaction wave with the granular material and the gas filtration, which affects the particles by the drag forces between the two phases. Inside a material with a permeability coefficient f〉0.001 mm2 the transmitted wave moves with a constant velocity which is largely governed by the gas filtration. For low permeability materials ( f〈0.0003 mm2) the transmitted wave trajectory strongly depends on the compaction wave propagation. In such cases the compaction wave was found to be unsteady and its acceleration was higher in material having low material densities. The maximum compressive stress values, P c , reached at the shock tube end-wall, covered by the materials under investigation, manifested as an unsteady pressure peak twice as large as the gas pressure P 5, measured ahead of the layer. Comparing the present data with those available in the literature showed that the amplitude of the unsteady pressure peak was higher in materials having low effective densities, γ, and small permeability coefficients f. Contrary to flexible foams where the available experimental data indicated that the compressive stress in the post peak period converges to P 5=P g , the results obtained in the present study indicated that during the test time the compressive stress, P s , was well preserved in the material and for most of the sample length its value was within the range P s 〉P 5〉P g .
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  Certain aspects of wave propagation and the dynamic reaction of a granular material when subjected to a long-duration impulse load are studied. In the majority of studies published on this subject the unsteady pressure behavior at the end-wall covered by a layer of granular material was observed and documented. However, up to now little attention was given to explaining the physical mechanism of this process. Experimental results, obtained in the course of this study, regarding the pressure fields inside granular layers of different materials, clearly show that the compaction effect strongly depends on the characteristics of the medium. This phenomenon manifests itself by changing the gas-particle interaction in the course of the gas filtration, and by variation in the contribution of the different forces and effective stress, σ, to the energy exchange between the gas, the particles and the shock-tube wall. The material permeability,  f, the relative density, ν, and the particle response time, τ p , are the most important parameters affecting the stress formation at the end-wall covered by the granular layer. In addition to the effect of the material parameters, the effective stress, σ, was found to strongly depend on the granular layer height, h. Based on detailed pressure measurements a qualitative analysis regarding the role of the particle rearrangement in the formation of the unsteady peak at the end-wall was performed. The phenomenology of the particle–particle interaction includes rotation and consolidation of the granules and movement or sliding of particle planes within the layer over each other. Most of these processes are frictional in their nature. They are related to the energy losses and affect the profile and magnitude of the compressive stress as measured at the shock-tube end-wall covered by the granular layer.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 70 (1996), S. 347-355 
    ISSN: 1432-0738
    Keywords: Key words Human metabolism ; Pharmacokinetics ; Population toxicokinetics ; Tetrachloroethylene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  In assessing the distribution and metabolism of toxic compounds in the body, measurements are not always feasible for ethical or technical reasons. Computer modeling offers a reasonable alternative, but the variability and complexity of biological systems pose unique challenges in model building and adjustment. Recent tools from population pharmacokinetics, Bayesian statistical inference, and physiological modeling can be brought together to solve these problems. As an example, we modeled the distribution and metabolism of tetrachloroethylene (PERC) in humans. We derive statistical distributions for the parameters of a physiological model of PERC, on the basis of data from Monster et al. (1979). The model adequately fits both prior physiological information and experimental data. An estimate of the relationship between PERC exposure and fraction metabolized is obtained. Our median population estimate for the fraction of inhaled tetrachloroethylene that is metabolized, at exposure levels exceeding current occupational standards, is 1.5% [95% confidence interval (0.52%, 4.1%)]. At levels approaching ambient inhalation exposure (0.001 ppm), the median estimate of the fraction metabolized is much higher, at 36% [95% confidence interval (15%, 58%)]. This disproportionality should be taken into account when deriving safe exposure limits for tetrachloroethylene and deserves to be verified by further experiments.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 243-245 (Nov. 1996), p. 511-514 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract The objectives of this research were to determine whether melanotropin receptors are characteristic membrane markers of human epidermal melanocytes. Methodologies were developed to visualize these receptors by light microscopy. Multiple copies (up to a thousand) of [Nle4,D-Phe7]α-MSH, a superpotent analog of α-melanocyte stimulating hormone (α-MSH), were conjugated to a macromolecular carrier, large polyamide beads (macrospheres). Incubation in (the presence of the I conjugated macrospheres resulted in binding of human epidermal melanocytes to the macrospheres. Specificity of the binding of melanocytes of the melanotro-pin-conjugated macrospheres was demonstrated by several studies: (i) Binding of melanocytes to the conjugate was specific since it could be blocked by prior incubation of the cells in the presence of (the unconjugated hormone analog: (ii) The macrospheres after removal of the bound ligand did not bind to the melanocytes: (iii) Another peptide hormone ligand (e.g., a substance-P analog) attached to the macrospheres failed to bind to the melanocytes: (iv) BI6/F10 mouse melanoma cells known lo express melanotropin receptors bound to the macrospheres; (v) Cells of nomnelanocyte origin (e.g., mammary cancer cells, lung cancer cells, fibroblasts) did not bind lo the macrospheres. One exception was that human epidermal keratinocytes also expressed melanotropin receptors as determined by all the criteria established for epidermal melanocyles. Thus, cell specific melanotropin receptors appear to be characteristic cell surface markers of epidermal melanocytes and keratinocytes.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 5615-5617 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have studied the magnetization and finite-size effects of thin Gd layers in sputter-deposited Gd/W multilayers. The interfacial Gd atoms lose about 9% of their moment, as the result of being in proximity with W. Annealing the multilayers at high temperatures improves the crystalline quality and sharpens the susceptibility peaks. The Curie temperature TC decreases with decreasing dGd according to the finite-size scaling relation [TC(∞)−TC(d)]/TC(∞)=(d/d0)−λ. The shift exponent λ has been found to be 1.5±0.1 and the constant d0 to be 13 A(ring). © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 6735-6740 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: High-peak-power lasers are typically used as pump sources in nonlinear optical measurements. Intrinsic to these sources are pulse-to-pulse output energy instabilities. We report on how pump instabilities affect the measurement of nonlinear susceptabilites and develop theory which relates statistical parameters of a general, arbitrary pump energy probability distribution to those of its corresponding mth harmonic output. The relation leads to a simple method of data analysis whereby pump instabilities can be used as a tool in determining the nonlinear susceptibility of a material. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 72 (1998), S. 909-911 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Metallic oxide films of SrRuO3 deposited on (001) SrTiO3 by pulsed laser deposition have been investigated by transmission electron microscopy (TEM) techniques. These films have a single crystalline structure with an extremely smooth surface. A TEM study of cross-sectional samples shows that the film grew epitaxially on the (001) surface of the SrTiO3 substrate. The films grew along the [110] directions with an in-plane orientation relationship of either SrRuO3[1¯10]//SrTiO3 [100] and SrRuO3[001]//SrTiO3[010], or SrRuO3[11¯0]//SrTiO3[010] and SrRuO3[001]//SrTiO3 [100]. Domains with a rotation of 90° around SrRuO3[110] were observed in the dark-field image of plan-view samples. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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