Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    F-Center Formation by K-Shell Excitation in KBr, RbCI and KI (1996)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 239-241 (Nov. 1996), p. 587-590 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/02/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.239-241.587.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Coordination of Thiocyanate Ions to Rare Earth Ions in Concentrated Aqueous Rare Earth Thiocyanate Solutions (1999)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 315-317 (July 1999), p. 494-499 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/04/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.315-317.494.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Spatial and temporal expression pattern of Bombyx fork head/SGF-1 gene in embryogenesis (1996)
    Springer
    Development genes and evolution 206 (1996), S. 80-85 
    Details
    ISSN: 1432-041X
    Keywords: Key words fork head ; SGF-1 ; Silk gland ; Salivary gland ; Gut
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  The embryonic expression of Bombyx fkh/SGF-1 gene has been analysed using in situ hybridization and immunohistochemistry. Both transcripts and protein were first detected in the most anterior and posterior regions at the time of germ anlage formation, and were successively expressed in the foregut and hindgut at later stages. A weaker expression was also detected in the elongated midgut. By the time embryo retraction was finished transcripts and protein were also detectable in the invaginated whole silk glands, and after the blastokinesis stage the products were restricted to the middle and posterior silk glands achieving a state required for the SGF-1 distribution for later stages. Expression could also be detected in the central and peripheral nervous systems. From these observations, we propose that Bombyx Fkh/SGF-1 may play a role in organogenesis processes such as those of the gut, silk glands, and nervous systems, act as a region specific homeotic gene, and in spite of clear embryonic developmental differences between Drosophila and Bombyx, two terminals may be determined by region specific genes such as Bombyx fkh/SGF-1 as opposed to segmental development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004270050033
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Embryonic silk gland development in Bombyx: molecular cloning and expression of the Bombyx trachealess gene (1999)
    Springer
    Development genes and evolution 209 (1999), S. 507-514 
    Details
    ISSN: 1432-041X
    Keywords: Key words trachealess ; Silk gland ; Trachea ; Bombyx mori
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  We describe embryonic development of the Bombyx silk gland. To extend the analysis further we isolated a Bombyx counterpart gene ofthe Drosophila trachealess (trh) gene. Bombyx trh encodes a protein of 849 amino acids. When compared with the amino acid sequence of Drosophila trh, the identity of Bombyx bHLH, PAS-A and PAS-B domains is 100%, 97%, and 80%, respectively. Northern blot analysis revealed the presence of a single Bombyx trh transcript of 5.4 kb. We analyzed the expression pattern of the Bombyx trh transcript during embryogenesis by in situ hybridization. Bombyx trh mRNA was first detected in the tracheal primordial cells at around embryonic stage 18. Thereafter levels of Bombyx trh mRNA increased, and the high expression level was maintained until hatching. At embryonic stage 19 the transcript was also detected in the posterior basal region of the labial segment from where the silk gland invaginates. By the blastokinesis stage (around stage 23), the silk gland was lengthened, and, interestingly, the Bombyx trh transcript was restricted to the anterior silk gland. These results suggest that Bombyx trh plays a role in the formation of the trachea and the anterior silk glands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004270050283
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Association of aldehyde dehydrogenase with inheritance of NIDDM (1996)
    Springer
    Diabetologia 39 (1996), S. 1115-1118 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Aldehyde dehydrogenase ; chlorpropamide alcohol flushing test ; diabetes mellitus ; diabetic retinopathy ; ALDH2.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To investigate the influence of the mitochondrial aldehyde dehydrogenase 2 (ALDH2) genotype on the clinical features of diabetes, 212 Japanese patients with non-insulin-dependent diabetes mellitus (NIDDM) (154 males and 58 females aged 17–83 years; mean age 58.2 years) were investigated. Genotyping of ALDH2 was performed by the polymerase chain reaction – restriction fragment length polymorphism (PCR-RFLP) method. The pattern of inheritance of diabetes and various clinical parameters was compared between active and inactive ALDH2 groups. Of the 212 subjects, 120 had active ALDH2 and 92 had inactive ALDH2. The percentage of patients with a diabetic mother was higher in the inactive ALDH2 group (32.6 %) than in the active ALDH2 group (19.2 %) (p 〈 0.05). The prevalence of proliferative retinopathy was lower in the inactive ALDH2 group than in the active ALDH2 group (p 〈 0.05). However, other clinical parameters showed no difference. We conclude that maternal inheritance of diabetes was common in the inactive ALDH2 group. The finding is suggestive of a relationship between alcohol intolerance and inheritance of diabetes. We speculate that the interaction between mitochondrial DNA and ALDH2 inactivity causes an increase of mitochondrial DNA mutations or deletions, thereby inducing the maternal inheritance of diabetes. The relationship of the ALDH2 genotype with proliferative retinopathy is interesting, because it resembles that of chlorpropamide alcohol flushing with severe diabetic retinopathy. The interaction of aldehyde dehydrogenase isoenzymes might have an aetiological role, since aldehyde dehydrogenase 1 plays an important part in oxidation of retinal to retinoic acid. However, the number of affected patients with proliferative retinopathy was small, hence, our result should be considered as a preliminary finding. [Diabetologia (1996) 39: 1115–1118]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400662
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro (1998)
    Springer
    Diabetologia 41 (1998), S. 1024-1028 
    Details
    ISSN: 1432-0428
    Keywords: Keywords CD38 gene ; susceptibility ; missense mutation ; Type II diabetes mellitus ; cyclic ADP-ribose ; ADP-ribosyl cyclase ; cyclic ADP-ribose hydrolase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cyclic adenosine 5′diphosphate-ribose (cADPR) is thought to have a second messenger role in insulin secretion through mobilisation of Ca2 +. As human lymphocyte antigen CD38 has both ADP-ribosyl cyclase and cADPR hydrolase activity, it may be important in glucose-induced insulin secretion in islets. Thirty one randomly selected Japanese patients with Type II diabetes mellitus who had first-degree and/or second-degree relative(s) with Type II diabetes mellitus were screened for mutations of this gene using single-stranded conformation polymorphism. Two variant patterns in exon 3 and exon 4 of the CD38 gene were identified. The variant in exon 3 resulted in an amino acid substitution from Arg140 (CGG) to Trp (TGG). The Arg140Trp mutation was observed in 4 of 31 patients, and allele frequencies were significantly different in patients and the control subjects (p = 0.004). One patient with this mutation has two missense mutations on beta cell/liver glucose transporter (GLUT2) gene; her mother, who has impaired glucose tolerance, also has this mutation on the CD38 gene and one missense mutation on the GLUT2 gene. Enzyme activity studies using COS-7 cells expressing the Arg140Trp mutation showed a reduction in ADP-ribosyl cyclase and cADPR hydrolase activity of around 50 %. The Arg140Trp mutation on CD38 thus appears to contribute to the development of Type II diabetes mellitus via the impairment of glucose-induced insulin secretion in the presence of other genetic defects. [Diabetologia (1998) 41: 1024–1028]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250051026
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    No association of ALDH2 genotype in MELAS (1997)
    Springer
    Diabetologia 40 (1997), S. 1241-1242 
    Details
    ISSN: 1432-0428
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050814
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Association of aldehyde dehydrogenase with inheritance of NIDDM (1996)
    Springer
    Diabetologia 39 (1996), S. 1115-1118 
    Details
    ISSN: 1432-0428
    Keywords: Aldehyde dehydrogenase ; chlorpropamide alcohol flushing test ; diabetes mellitus ; diabetic retinopathy ; ALDH2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To investigate the influence of the mitochondrial aldehyde dehydrogenase 2 (ALDH2) genotype on the clinical features of diabetes, 212 Japanese patients with non-insulin-dependent diabetes mellitus (NIDDM) (154 males and 58 females aged 17–83 years; mean age 58.2 years) were investigated. Genotyping of ALDH2 was performed by the polymerase chain reaction — restriction fragment length polymorphism (PCR-RFLP) method. The pattern of inheritance of diabetes and various clinical parameters was compared between active and inactive ALDH2 groups. Of the 212 subjects, 120 had active ALDH2 and 92 had inactive ALDH2. The percentage of patients with a diabetic mother was higher in the inactive ALDH2 group (32.6%) than in the active ALDH2 group (19.2%) (p〈0.05). The prevalence of proliferative retinopathy was lower in the inactive ALDH2 group than in the active ALDH2 group (p〈0.05). However, other clinical parameters showed no difference. We conclude that maternal inheritance of diabetes was common in the inactive ALDH2 group. The finding is suggestive of a relationship between alcohol intolerance and inheritance of diabetes. We speculate that the interaction between mitochondrial DNA and ALDH2 inactivity causes an increase of mitochondrial DNA mutations or deletions, thereby inducing the maternal inheritance of diabetes. The relationship of the ALDH2 genotype with proliferative retinopathy is interesting, because it resembles that of chlorpropamide alcohol flushing with severe diabetic retinopathy. The interaction of aldehyde dehydrogenase isoenzymes might have an aetiological role, since aldehyde dehydrogenase 1 plays an important part in oxidation of retinal to retinoic acid. However, the number of affected patients with proliferative retinopathy was small, hence, our result should be considered as a preliminary finding.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400662
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Spatial and temporal expression pattern of POU-M1/SGF-3 in Bombyx mori embryogenesis (1997)
    Springer
    Development genes and evolution 206 (1997), S. 494-502 
    Details
    ISSN: 1432-041X
    Keywords: Key words POU domain ; SGF-3 ; Cf1a ; Silk gland ; Salivary gland
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  The expression pattern of the POU-M1/SGF-3 gene during Bombyx embryogenesis has been analysed using in situ hybridization and immunohistochemistry. At the early embryo retraction stage, both the transcripts and protein were first detected in precursor cells of the prothoracic glands in the labial segment, in the oenocytes in the A1–A8 segments and in invaginated regions in the mandibular and maxillary segments. The invaginated regions in the mandibular segment develop into the abductor plates in the lateral anterior region and the adductor plates in the posterior region. From the latter plates, the salivary glands elongate. The invaginated regions in the maxillary segment develop into the corpora allata in the anterior region and the subbuccal glands in the posterior region, which unite with tissues of the anterior region of the mandibular segment at later stages. After the embryo retraction stage, the transcripts and protein products also become detectable in the silk gland invagination points and, after the blastokinesis stage, the products are restricted to the entire anterior silk glands and to the anterior and middle parts of the middle silk glands. Expression can also be detected in a part of the hindgut, in the tracheal system and in some cells of the central nervous system. These results indicate that POU-M1/SGF-3 might play roles in the development of the silk glands, nervous system, tracheal system and other organs like the prothoracic glands and oenocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004270050080
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Effect of denervation on lymphocytes and dendritic cells in the rat circumvallate and foliate papillae (1997)
    Springer
    Anatomy and embryology 196 (1997), S. 447-455 
    Details
    ISSN: 1432-0568
    Keywords: Key words γδ T cell ; Langerhans cell ; Taste bud ; Denervation ; Tongue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The distribution of dendritic (Langerhans) cells and lymphocytes in rat circumvallate and foliate papillae was examined by immunohistochemistry and electron microscopy. Light microscopic immunohistochemistry using anti-OX62 antibody, which recognizes both γδ T lymphocytes and dendritic cells, showed that many OX62-immunoreactive cells had invaded into the trench wall epithelium from the connective tissue at 6 days after sectioning of the glossopharyngeal nerves. The presence of OX62-immunoreactive cells in the epithelium was observed up to 17 days after the denervation, by which time the taste buds had disappeared from the trench wall. The OX62-positive cells were again observed in the connective tissue at 24 and 40 days when taste buds regenerated. The local circulation of OX62-positive cells between the epithelium and connective tissue is suggested. Most of the OX62-positive cells in the epithelium of circumvallate and foliate papillae were suggested to be γδ T cells, since they were round or spindle-shaped. Electron micrographs of OX62-positive cells also indicated that they were lymphocytes. Furthermore, they expressed CD3 but lacked CD4 and CD8 surface markers. A few dendritic cells, which reacted with anti-OX6 antibody, were observed in the circumvallate and foliate papillae in the control and denervated animals, and they were irregular in shape with long cytoplasmic processes. Electron micrographs taken at 6 days showed that the dendritic cells, which were characterized by the presence of Birbeck granules in the cytoplasm, were in contact with lymphocytes. The finding suggests that γδ T lymphocytes and dendritic cells in the rat circumvallate and foliate papillae interact with each other to respond to changes such as the presence or absence of taste buds in the epithelium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004290050112
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...