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  • Artikel: DFG Deutsche Nationallizenzen  (11)
  • 1990-1994  (11)
Datenquelle
  • Artikel: DFG Deutsche Nationallizenzen  (11)
Materialart
Erscheinungszeitraum
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Occupational asthma caused by chromium (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 24 (1994), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Summary. We report four cases of occupational asthma caused by chromium salts, three of whom showed dual and one isolated early asthmatic responses on specific chromium bronchoprovocation test (BPT). All of them were ex–smokers. Two showed positive skin–prick tests to 10mg/ml of Cr2(SO4)3, but negative results on patch testing. The remaining two showed positive results on patch testing with Cr2(SO4)3. Three had airway hyperresponsiveness to methacholine on initial examination. Although initial methacholine airway challenge testing showed a negative result in the remaining patient, airway hyperresponsiveness developed transiently 24 h after an isolated immediate asthmatic reaction induced by chromium. Three patients were reassessed after complete avoidance of chromium. Two subjects showed marked improvement of their symptoms with significant increases of PC20 methacholine. We conclude that chromium induces occupational asthma in exposed workers. Further investigations are needed to clarify the pathogenetic mechanism.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1994.tb00972.x
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  • 2
    Digitale Medien
    Digitale Medien
    Occupational asthma caused by two herb materials, Dioscorea batatas and Pinellia ternata (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 24 (1994), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Abstract. There have been very few cases of occupational allergies caused by herb materials. In this paper, we report a case of occupational asthma and rhinitis caused by two herb materials. Dioscorea batatas and Pinellia ternata which are known as Sanyak and Banha respectively. The patient had strong positive responses to grass pollens and cat fur, as well as to Sanyak and Banha extracts on skin-prick tests. Bronchoprovocation tests showed a dual asthmatic response to Sanyak whereas only an early asthmatic response to Banha. Serum specific IgE and IgG4 antibodies to Sanyak were detected by enzyme-linked immunosorbent assay (ELISA) but there was no specific IgE antibody binding to Banha. In order to further characterize the allergenie component of these extracts, sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and electroblotting studies were also performed. Three IgE binding components (29000, 57000, 63000 Da) were detected within the Sanyak extracts, but no IgE-binding component was noted within the Banha extracts. It is suggested that Sanyak can induce IgE-mediated bronchoconstriction in an exposed worker. Further studies are needed to investigate the pathogenetic mechanism triggered by Banha.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1994.tb00955.x
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  • 3
    Digitale Medien
    Digitale Medien
    The significance of specific IgG and IgG4 antibodies to a reactive dye in exposed workers (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 21 (1991), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: To evaluate the significance of specific IgG and specific IgG4 in the development of work-related respiratory symptoms, specific IgG and specific IgG4 to Black GR-human serum albumin (HSA) conjugate were measured by ELISA in 309 dye-exposed workers and 63 unexposed patients as negative controls. A survey revealed that 78 (25.2%) had work-related lower respiratory symptoms with or without nasal, skin or eye symptoms. Specific IgG and specific IgG4 were detected in 23% and 14% of the exposed workers, respectively. The prevalence of specific IgG and specific IgG4 was significantly higher in smokers and workers with specific IgE or those with lower respiratory symptoms (P 〈 0.05), but was not associated with work station, duration of dye exposure or atopy. These results suggested that the existence of specific IgG to Black GR HSA might represent a response to Black GR exposure and be closely related with work-related respiratory symptoms.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1991.tb01668.x
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  • 4
    Digitale Medien
    Digitale Medien
    Hypersensitivity pneumonitis induced by Penicillium expansum in a home environment (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 24 (1994), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: An episode of fever, cough, shortness of breath and leucocytosis developed in a 31-year-old atopic housewife from mould exposure in her home environment is evaluated. A chest radiograph revealed diffuse tiny nodular infiltrations in both whole lung fields. Spirometry revealed a severe restrictive type of ventilation impairment. Bronchoalveolar lavage (BAL) showed an increased lymphocyte count with reversed CD4 +/CD8 + ratio and transbronchial lung biopsy showed markedly increased lymphocytic infiltration in alveolar septa. Fungal cultures in the air of her home were positive for Penicillium expansum and other fungi. Double immunodiffusion test with the patient's serum showed two precipitin bands to P. expansum antigens. Her symptoms, abnormal findings of radiograph, and spirometric abnormalities disappeared after 2 months' avoidance. The serum precipitin disappeared after 1 month's avoidance. This study indicates that the patient had hypersensitivity pneumonitis (HP) on exposure to P. expansum in her home environment.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1994.tb00251.x
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  • 5
    Digitale Medien
    Digitale Medien
    Heterogeneity of IgE antibody response to reactive dye in sera from four different sensitized workers (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 22 (1992), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: We studied RAST and RAST inhibition tests to black GR, the most frequent sensitizer among several reactive dyes in our previous study, in order to evaluate the specificity of IgE antibodies to hapten or new antigenic determinants and the crossreactivity between two reactive dyes, black GR and orange 3R, in sera from four different sensitized workers. RAST inhibition studies with black GR-human serum albumin (HSA) conjugate discs demonstrated that black GR-HSA conjugates were the most effective inhibitors. Orange 3R-HSA conjugates, unconjugated forms of black GR and orange 3R were weak inhibitors in two patients and non-inhibitory in one patient, whereas they caused strong dose-dependent inhibitions in one patient. These results suggested that the IgE response to black GR-HSA conjugates might be heterogenous and the cross-reactivity between two reactive dyes differed from one patient to another.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1992.tb00176.x
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  • 6
    Digitale Medien
    Digitale Medien
    The First Data from the MACHO Experiment (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 688 (1993), S. 0 
    Details
    ISSN: 1749-6632
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1749-6632.1993.tb43945.x
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  • 7
    Digitale Medien
    Digitale Medien
    Possible gravitational microlensing of a star in the Large Magellanic Cloud (1993)
    [s.l.] : Nature Publishing Group
    Nature 365 (1993), S. 621-623 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] The MACHO Project7'8 uses the gravitational microlens signature to search for evidence of MACHOs in the Galactic halo, which is thought to be at least three times as massive as the visible disk2. (Two other groups are attempting a similar search9'10.) If most of our Galaxy's dark matter resides ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/365621a0
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  • 8
    Digitale Medien
    Digitale Medien
    Consolidation of amorphous powders by the forced rolling process (1990)
    Springer
    Journal of materials science 9 (1990), S. 195-197 
    Details
    ISSN: 1573-4811
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00727713
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  • 9
    Digitale Medien
    Digitale Medien
    Mechanical alloying of Fe-B alloys (1992)
    Springer
    Journal of materials science 27 (1992), S. 153-160 
    Details
    ISSN: 1573-4803
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau
    Notizen: Abstract Mechanical alloying (MA) of Fe-B alloy systems using a conventional ball mill has been performed. The structure change of Fe100−x B x for the composition range 10≤x≤90 has been investigated using X-ray diffractometry, thermal analysis, transmission electron microscopy, scanning electron microscopy and Mössbauer spectroscopy. According to the X-ray diffraction analysis, the sequences of transformation have been classified into three groups,x≤20, 25≤x≤35 andx≥50 for Fe100−x B x . The amorphous phase whose composition is nearlyx=30, first appeared for the whole composition range. This amorphous phase changed into a tetragonal Fe2B-like compound on further milling for 1000 h. On further milling of thex= 50 sample, the Fe2B compound phase disappeared and orthorhombic FeB compound appeared.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00553851
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  • 10
    Digitale Medien
    Digitale Medien
    Mechanical alloying of Fe-B alloys (1992)
    Springer
    Journal of materials science 27 (1992), S. 153-160 
    Details
    ISSN: 1573-4803
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau
    Notizen: Abstract Mechanical alloying (MA) of Fe-B alloy systems using a conventional ball mill has been performed. The structure change of Fe100−x B x for the composition range 10≤x≤90 has been investigated using X-ray diffractometry, thermal analysis, transmission electron microscopy, scanning electron microscopy and Mössbauer spectroscopy. According to the X-ray diffraction analysis, the sequences of transformation have been classified into three groups,x≤20, 25≤x≤35 andx≥50 for Fe100−x B x . The amorphous phase whose composition is nearlyx=30, first appeared for the whole composition range. This amorphous phase changed into a tetragonal Fe2B-like compound on further milling for 1000 h. On further milling of thex= 50 sample, the Fe2B compound phase disappeared and orthorhombic FeB compound appeared.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02403658
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