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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Review of income and wealth 37 (1991), S. 0 
    ISSN: 1475-4991
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Since household wealth surveys have been widely used to study saving and other issues, it is important to examine the reliability of the various survey estimates of wealth. In this paper the authors assess the quality characteristics of the National Longitudinal Survey of Mature Men and the Retirement History Survey, as compared to the 1983 Survey of Consumer Finances. We find that the NLS and especially the RHS underreport wealth and wealth concentration. The underestimates of wealth held in the form of common stock, business equity, and investment real estate equity are substantial. The principal problem lies in underrepresentation of both tails of the wealth and income distributions, with the consequences of underrepresenting the upper tail being especially serious for wealth measurement. We examine several potential reasons for the underrepresentation.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] We have isolated the gene for human type I keratin 9 (KRT9) and localised it to chromosome 17q21. Patients with epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant skin disease, were investigated. Three KRT9 mutations, N160K, R162Q, and R162W, were identified. All the mutations are ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 26 (1993), S. 135-137 
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: The cryostat for 8 〈 T 〈 300 K presented here, based on a closed-cycle cryogenic engine, optimizes the powder-grain statistics of the sample by the use of a cold sample spinner working within an open helium-gas atmosphere for thermal contact. The compact design of the cooling stage adapted to the Bragg–Brentano-type diffraction geometry provides for a large open interval, 0 〈 2Θ 〈 180°, of diffraction angles. A wide variety of sample holders allows measurements with plane powder samples and thin films at low temperatures under variable orientation.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1437-3262
    Keywords: Pan-African ; Granitoids ; Geochronology ; Isotope geochemistry ; Mozambique Belt ; Somalia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Granitoids within the Precambrian basement of north-eastern and southern Somalia are subdivided on the basis of geology, geochronology and petrology into three different assemblages. The post-kinematic assemblage in north-eastern Somalia (≈ 630 Ma) comprises granodiorites and granites which belong to a medium-K calc-alkaline suite. Average initial Sr, Nd and Pb isotopic ratios [Sri = 0.7048, ɛNd = −1.8, 206Pb/204Pb(i) = 17.704 and 207Pb/204Pb(i) = 15.611] indicate that these melts were derived from a mantle or juvenile crustal source with only slight involvement of pre-existing crust as a contaminant. Two different assemblages are found in southern Somalia. The older assemblage is composed of crustal anatectic, synkinematic, parautochthonous granites (≈ 600 Ma) related to amphibolite facies retrogression of an intensively reworked pre-Pan-African crust [Sri = 0.7100, ɛNd = −8.4, 206Pb/204Pb(i) = 15.403 and 207Pb/204Pb(i) = 15.259]. These monzo- and syenogranites are moderately potassic and peraluminous. The younger assemblage (≈ 470 Ma) consists of post-kinematic monzonites to syenogranites with A-type affinities. Initial Sr, Nd and Pb isotopic data for this metaluminous assemblage [Sri = 0.7114, ɛNd = −13.1, 207Pb/204Pb(i) = 16.913 and 207Pb/204Pb(i) = 15.512] indicate a significant lower crustal component but, however, also a mantle signature. The late Proterozoic to early Palaeozoic granitoids in Somalia thus express contrasting regimes, characterized by strong juvenile input in the north, close to the Arabian-Nubian Shield, whereas intense crustal reworking with little addition of juvenile material prevailed in the south. Somalia was definitively not a cratonic area during the Pan-African, but a zone of high crustal mobility.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1437-3262
    Keywords: Pan-African ; Granitoids ; Geochronology ; Isotope geochemistry ; Mozambique Belt ; Somalia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Granitoids within the Precambrian basement of north-eastern and southern Somalia are subdivided on the basis of geology, geochronology and petrology into three different assemblages. The post-kinematic assemblage in north-eastern Somalia (≈ 630 Ma) comprises granodiorites and granites which belong to a medium-K calc-alkaline suite. Average initial Sr, Nd and Pb isotopic ratios [Sri = 0.7048, ɛNd = −1.8,206Pb/204Pb(i) = 17.704 and207Pb/204Pb(i) = 15.611] indicate that these melts were derived from a mantle or juvenile crustal source with only slight involvement of pre-existing crust as a contaminant. Two different assemblages are found in southern Somalia. The older assemblage is composed of crustal anatectic, synkinematic, parautochthonous granites (≈ 600 Ma) related to amphibolite facies retrogression of an intensively reworked pre-Pan-African crust [Sri = 0.7100, ɛNd = −8.4,206Pb/204Pb(i) = 15.403 and207Pb/204Pb(i) = 15.259]. These monzo- and syenogranites are moderately potassic and peraluminous. The younger assemblage (≈ 470 Ma) consists of post-kinematic monzonites to syenogranites with A-type affinities. Initial Sr, Nd and Pb isotopic data for this metaluminous assemblage [Sri = 0.7114, ɛNd = −13.1,207Pb/204Pb(i) = 16.913 and207Pb/204Pb(i) = 15.512] indicate a significant lower crustal component but, however, also a mantle signature. The late Proterozoic to early Palaeozoic granitoids in Somalia thus express contrasting regimes, characterized by strong juvenile input in the north, close to the Arabian-Nubian Shield, whereas intense crustal reworking with little addition of juvenile material prevailed in the south. Somalia was definitively not a cratonic area during the Pan-African, but a zone of high crustal mobility.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 282 (1990), S. 98-102 
    ISSN: 1432-069X
    Keywords: Atopic dermatitis ; Family study ; Genetic recurrence risk ; Genetic counselling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The history of 188 Caucasian patients with atopic dermatitis (AD) and of 2,151 family members has been analyzed. Of the AD patients 48% suffered from respiratory atopy (36% rhinitis, 28% asthma, and 15% both). AD showed by far the earliest onset of all atopic diseases: 50% of our patients had skin lesions before the age of 2 years and 60% before the age of 5 years. In contrast, symptoms of allergic asthma developed in 40% of AD patients before the age of 5 years in comparison with only 25% who had allergic rhinitis. AD affects females more frequently than males (male to female ratio 1∶1.5), regardless of whether additional respiratory atopies are present or not. In contrast, respiratory atopies develop more frequently in males than in females (male to female ratio 1.5∶1). Mothers with respiratory atopy more often have atopic children (26%) than do fathers with respiratory atopy (13%). Finally, risk figures for genetic counselling are given. In short, the general risk of developing AD (3%) and atopy (7%) increases by a factor of two with each first-degree family member already suffering from atopy.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-069X
    Keywords: Cutaneous T-cell lymphoma ; Cytogenetics ; Extracorporeal photopheresis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of extracorporeal photopheresis (EP) on various cytogenetic parameters has been investigated. During EP the photoactivatable agent 8-methoxypsoralen (8-MOP) was administered orally. After 2 h a leukocyteenriched blood fraction was collected by haemocentrifugation, irradiated with UVA extracorporeally, and reinfused to the patient. Two patients suffering from cutaneous T-cell lymphoma showed a marked clinical improvement in response to therapy. In order to investigate the cytogenetic effects and mutagenic risks of EP, the mitotic index (MI), the type and number of chromosomal aberrations and the rate of sister chromatid exchanges (SCE) were studied. Following EP treatment the patients' lymphocytes were cultured and stimulated with phytohaemagglutinin (PHA) for 48 or 72 h. The cultured lymphocytes showed a decreased MI after 48 h as an indicator of cytotoxic effects, but not after 72 h. In lymphocyte cultures not stimulated with PHA, the MI was decreased even after 72 h. The number of chromosomal aberrations and SCE were increased upon treatment, but only transiently, returning to basal levels between consecutive treatments. Our data provides no evidence for increased mutagenic risk as a consequence of effective EP treatment.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 30 (1910), S. 351-355 
    ISSN: 1432-041X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Mutations in the human keratin 9 gene have recently been shown to be involved in the etiology of palmoplantar keratoderma (PPK). We have investigated eleven unrelated German kindreds with the epidermolytic variant of PPK (EPPK) for mutations in the keratin 9 gene. We have identified two novel mutations, M156V and Q171P, both in the coil 1A segment of keratin 9. Mutation M156V was detected in two unrelated patients with EPPK, and mutation Q171P was shown to cosegregate with the disease in a large four-generation family. These findings confirm the functional importance of coil 1A integrity for heterodimerisation in keratins and for intermediate filament assembly. Our results provide further evidence for mutational heterogeneity in EPPK, and for the involvement of keratins in diseases of hyperkeratinisation and epidermolysis.
    Type of Medium: Electronic Resource
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