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  • 1
    Electronic Resource
    Electronic Resource
    SP-40,40 is a constituent of Alzheimer's amyloid (1992)
    Springer
    Acta neuropathologica 83 (1992), S. 260-264 
    Details
    ISSN: 1432-0533
    Keywords: S-protein ; Sulfated glycoprotein 2 ; Clusterin ; Testosterone repressed prostate message-2 ; T64
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cerebrospinal fluid (CSF), serum and seminal plasma contain a small amount of SP-40,40, a modulatory protein of the human complement system. The SP-40,40 in each body fluid was different in molecular size on SDS-PAGE, and glioblastoma cells, hepatoma cells and testicular tumor cells produced SP-40,40, while neuroblastoma cells did not. Therefore, it was estimated that CSF SP-40,40 originated in glia cells, serum SP-40,40 in liver cells and seminal plasma SP-40,40 in testicular cells. SP-40,40 concentrations in CSF of the patients with Alzheimer's disease and the patients with cerebral tumor were higher than those of normal donors. β-Amyloid deposits in the brains of the patients with Alzheimer's disease were stained with an anti-SP-40,40 monoclonal antibody (mAb) but not with an anti-S-protein mAb, while cellular processes around β-amyloid were stained with an anti-S-protein mAb but not with an anti-SP-40,40 mAb. Therefore, β-amyloid contained SP-40,40 in a form different from that in the soluble membrane attack complex (SMAC, SC5b-9) of the complement, which contains S-protein as well as SP-40,40.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296787
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  • 2
    Electronic Resource
    Electronic Resource
    Sequestration of copper and zinc in the hepatopancreas ofArmadillidium vulgare latreille following exposure to lead (1991)
    Springer
    Bulletin of environmental contamination and toxicology 46 (1991), S. 894-900 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01689735
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of dorsal root entry zone lesion on spinal cord potentials evoked by segmental, ascending and descending volleys (1992)
    Springer
    Acta neurochirurgica 117 (1992), S. 135-142 
    Details
    ISSN: 0942-0940
    Keywords: Spinal cord potentials (SCPs) ; dorsal root entry zone (DREZ) lesion ; segmental, ascending, descending volleys
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The spinal cord potentials (SCPs) were recorded from the dorsal root entry zone (DREZ) and posterior epidural space in patients before and after dorsal root entry zone lesion (DREZL) during general anaesthesia. The SCPs from the DREZ activated by segmental, ascending and descending volleys were basically the same in fundamental waveform as those recorded from the posterior epidural space. Segmentally activated slow negative (N1) wave, reflecting synchronized activities of dorsal horn neurones, and positive (P2) wave, thought to indicate primary afferent depolarization, were affected by DREZL in all 4 subjects tested, even by contralateral stimulation, suggesting that these components of the segmental SCPs in man partly reflect the activities of the contralateral dorsal horn. The spike-like potentials activated by ascending volleys were not affected by DREZL, while the subsequent slow components were decreased in the lesioned level. This may indicate that ascending spinal cord tracts are not affected by the operation, and suggests that the origin of the slow components by ascending volleys lies at least in part in the segmental dorsal horn. The slow negative and positive components, recorded at a remote segment from DREZL, in response to the descending volleys, were augmented after DREZL, suggesting that activation of ascending or descending inhibition through a feedback loop via the supraspinal structures might occur at least transiently following DREZL. All components of the SCPs activated by descending volleys were decreased or disappeared in recording from the lesioned level, as expected. Thus, intra-operative recording of the SCPs during DREZL might be beneficial for monitoring and studying human spinal cord function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400610
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  • 4
    Electronic Resource
    Electronic Resource
    Transmission electron diffraction study of C70 phase transformation at low temperature (1992)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 61 (1992), S. 1171-1173 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: C70 grown on a NaCl substrate is observed by transmission electron microscopy (TEM) at low temperature (104 K). New spots that appear reproducibly in the electron diffraction (ED) at low temperature can be indexed as (m±1/2, n±1/2, 0) (m,n: integer) in a [001]hcp projection. The lattice constant a is lower at low temperature and the reduction ratio is a104 K/a300 K=1.02/1.06 nm=0.96±0.02, which is much lower than the value reported for C60. The ED of the low-temperature phase is observed below about 260 K, and an intermediate state is also detected in this temperature range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.107636
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  • 5
    Electronic Resource
    Electronic Resource
    Growth retardation and elemental differences in juvenile Armadillidium vulgare latreille exposed to lead nitrate (1992)
    Springer
    Bulletin of environmental contamination and toxicology 48 (1992), S. 70-76 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00197485
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  • 6
    Electronic Resource
    Electronic Resource
    Antigenic analysis of avian rotavirus VP6 using monoclonal antibodies (1993)
    Springer
    Archives of virology 131 (1993), S. 293-305 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Monoclonal antibodies (MAbs) were prepared to analyze antigens on the major inner capsid protein, VP 6 of avian group A rotavirus. Based on the results of a competitive binding assay using 15 MAbs directed against VP 6 of the PO-13 rotavirus strain, isolated from a pigeon in Japan, it was found that VP 6 of avian rotavirus possesses at least four spatially distinct antigenic sites. Two antigenic sites (I and II) were topologically distinct from the other two (III and IV), which were in close proximity. From the reaction of MAbs in indirect immunofluorescent antibody tests to a series of known rotaviruses, epitopes representing common antigens of all group A rotavirus including avian rotavirus were localized in sites II and III. One epitope in site IV appeared to have a subgroup antigenic specificity that reacted only with rotaviruses belonging to subgroup I. Interestingly, avian rotaviruses isolated from turkeys and chickens in Northern Ireland also reacted only with these subgroup I specific MAbs, but not with subgroup II specific MAb. This indicates that avian rotavirus has subgroup I specific antigen, which is antigenically similar to that of other mammalian rotavirus strains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01378633
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  • 7
    Electronic Resource
    Electronic Resource
    Secondary ion yields depending on the primary oxygen ion energy in cameca IMS-4f instrument (1994)
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 21 (1994), S. 864-869 
    Details
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The secondary ion yields of six element in silicon were measured as a function of the primary oxygen ion energy in a Cameca IMS-4f SIMS instrument. The ion yields of elements with a high ionization potential decrease steeply with primary ion energy owing to the decreasing surface oxygen concentration. The decrease of the ion yield depends on the ionization potential. This relation and the known relative sensitivity factors enable a semiquantitative analysis of impurities in silicon to be carried out without standard samples.A similar study combined with oxygen flooding shows that the yields are now very high and independent of the primary ion energy. Profile distortions due to segregation effects, however, can occur.A comparison of the ion yields obtained with and without energy offset under low and high oxygen surface coverage shows that the shape of the arsenic secondary ion energy distribution is drastically changed leading to pronounced differences in ion yields.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/sia.740211208
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