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  • 1
    Electronic Resource
    Electronic Resource
    High-power operation in InGaAs separate confinement heterostructure quantum well laser diodes (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 53 (1988), S. 1-3 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Lasing characteristics have been investigated systematically in long-wavelength InGaAs separate confinement heterostructure quantum well laser diodes (SCH QW LD's) with varied well thicknesses and number of wells, for the first time. Marked improvements in threshold current density and characteristic temperature values have been observed in SCH MQW LD's to SCH SQW LD's. Maximum cw output power of 46 mW at 20 °C has been achieved in SCH QW LD's with five wells, which is the highest among the long-wavelength quantum well LD's.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.100120
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  • 2
    Electronic Resource
    Electronic Resource
    Improvement of the bulk laser damage threshold of potassium dihydrogen phosphate crystals by reducing the organic impurities in growth solution (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 52 (1988), S. 420-421 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We obtained damage-resistant crystals of potassium dihydrogen phosphate (KDP) by reducing organic impurities in the growth solution. To prevent organic impurity exuded from the wall of the growth vessel, Pyrex glass was used. The residual organic impurities, which mainly derived from KDP raw powder, were reduced by photochemical dissociation using a combination of ultraviolet light and an oxidant (hydrogen peroxide). The resultant total organic carbon of the solution was less than 0.1 ppm. The damage threshold of the crystals grown from this solution was always high (20–22 J/cm2), which is about three times higher than that of crystals grown by conventional methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.99429
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  • 3
    Electronic Resource
    Electronic Resource
    Substrate-polarity dependence of metal-organic vapor-phase epitaxy-grown GaN on SiC (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 4531-4535 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Single-crystal gallium nitride was grown on each of the two polar {0001} planes of 6H-silicon carbide substrates utilizing metal-organic vapor-phase epitaxy. The substrate polarity is clearly shown to strongly influence the surface morphology and the photoluminescence property of the layer. The examination of the layer surfaces using x-ray photoelectron spectroscopy revealed that {0001} GaN grown on the basal planes of SiC changes its polarity in accordance with the substrate polarity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.341281
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  • 4
    Electronic Resource
    Electronic Resource
    A chromogenic limulus test for detection of microbes that decreases the laser damage threshold of potassium dihydrogen phosphate crystals (1987)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 61 (1987), S. 4696-4698 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The chromogenic limulus test has been applied for the first time to detect an organic impurity contained in potassium dihydrogen phosphate (KDP) crystals. Impurities arise from microbes present during crystal growth, and are responsible for a reduced laser damage threshold. A sensitivity of 10 pg/g KDP (10−5 ppm) was achieved, provided that the KDP solution was neutralized to ∼pH 7. Endotoxin content in the prismatic region of KDP crystals grown in a microbe-rich solution was approximately 100 pg/g KDP. The presence of an organic material in seemingly perfect KDP crystals could be experimentally confirmed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.338384
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  • 5
    Electronic Resource
    Electronic Resource
    High-resolution time-of-flight methods for studies on ionic fragmentation of molecules : INTERNATIONAL CONFERENCE ON SYNCHROTRON RADIATION INSTRUMENTATION (1989)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 60 (1989), S. 2193-2196 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The design and operation of the time-of-flight (TOF) mass spectrometer developed for ionic photofragmentation studies of molecules is described. Characteristics are summarized for three different operation modes of the TOF spectrometer; a pulse mode, a photoelectron–photoion coincidence mode, and a photoion–photoion coincidence mode. Experimental results for SiH4 are demonstrated as an example for the performance of the apparatus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1140819
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  • 6
    Electronic Resource
    Electronic Resource
    Scalings of implosion experiments for high neutron yield (1988)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 31 (1988), S. 2884-2893 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A series of experiments focused on high neutron yield has been performed with the Gekko-XII green laser system [Nucl. Fusion 27, 19 (1987)]. Deuterium–tritium (DT) neutron yield of 1013 and pellet gain of 0.2% have been achieved. Based on the experimental data from more than 70 irradiations, the scaling laws of the neutron yield and the related physical quantities have been studied. Comparison of the experimental neutron yield with that obtained by using a one-dimensional fluid code has led to the conclusion that most of the neutrons produced in the stagnation phase of the computation are not observed in the experiment because of fuel–pusher mixing, possibly induced by the Rayleigh–Taylor instability. The coupling efficiency and ablation pressure have been calculated using the ion temperature measured experimentally. A coupling efficiency of 5.5% and an ablation pressure of 50 Mbar have been obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.866997
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  • 7
    Electronic Resource
    Electronic Resource
    Peptide segment synthesis catalyzed by the semisynthetic enzyme thiolsubtilisin (1987)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 109 (1987), S. 3808-3810 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00246a064
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  • 8
    Electronic Resource
    Electronic Resource
    Regional Distribution and Characterization of Kinin in the CNS of the Rat (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 44 (1985), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The distribution of kinin in the CNS of the rat, which was extracted with n-butanol from an acidified homogenate, was determined using a bradykinin (BK) radioimmunoassay system. The immunoreactive kinin was widely distributed throughout the brain. The highest content was found in the pituitary gland (4,135 fmol BK Eq/g), followed by the medulla oblongata (912 fmol/g), cerebellum (549 fmol/g), and cortex (512 fmol/g). The kinin in the posterior pituitary was concentrated 4.5 times as much as in the anterior lobe. Serial dilution of brain extracts produced binding curves parallel to the standard radioimmunoassay curve. The purified brain kinin comigrated with authentic BK during CM-cellulose chroma tography and Sephadex LH-20 gel chromatography. Its molecular weight was estimated to be 1,127$45 by gel filtration, which coincides well with that of BK. Chymotrypsin degraded the extracted kinin and authentic BK, but trypsin did not. These data demonstrate that a peptide indistinguishable from BK exists in the rat brain. Furthermore, pituitary kinin was separated into BK (87%), Lys-BK (10%), and Met-Lys-BK (3%), using reverse phase HPLC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1985.tb07185.x
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  • 9
    Electronic Resource
    Electronic Resource
    Clinico-pathological features of squamous cell carcinoma of the oral cavity in patients 〈40 years of age (2005)
    Oxford, UK : Munksgaard International Publishers
    Journal of oral pathology & medicine 34 (2005), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Considerable controversy exists in the literature regarding the clinical course of young patients with oral squamous cell carcinoma (SCC). The purpose of this study was to evaluate the clinico-pathological features of oral SCC among young people.Methods:  From a cohort of 529 patients diagnosed with SCC, 35 (6.6%) were under the age of 40 years. This group was compared to a control group of 110 cases aged over 40 to determine if there were any differences in clinicopathological features between the two groups.Results:  In the young group there were 20 males and 15 females. The site was most frequently the tongue (51.3%), followed by the floor of the mouth, the buccal mucosa, and the upper and lower alveolus and gingiva. The local and regional control rate was 64.8% which was similar to that of older patients in this series.Conclusions:  The prognosis of oral SCC in the young patients does not appear to be different from that of the older population. Univariate analysis showed that clinical stage and the mode of invasion were the most significant prognostic factors in both younger and older patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.2004.00291.x
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  • 10
    Electronic Resource
    Electronic Resource
    Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 153 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Fibulin-5 was recently found as a secreted extracellular matrix protein that functions as a scaffold for elastic fibres. However, the distribution of fibulin-5 in human skin and its changes during the ageing process are not known.Objectives  To explore the involvement of fibulin-5 in skin ageing, the age-dependent changes in fibulin-5 localization in human skin were examined compared with those of other elastic fibre components including elastin, fibrillin-1 and fibulin-2.Methods  The distribution of elastin, fibrillin-1, fibrillin-2, fibulin-2 and fibulin-5 was investigated by means of immunohistochemistry using their specific antibodies. Skin samples were recovered from 12 healthy subjects undergoing plastic surgery. Ultraviolet (UV) B-irradiated or control nonirradiated buttock skin samples were obtained from two healthy volunteers at 2 days after the irradiation at 2 minimal erythemal doses.Results  In the reticular dermis of young sun-protected skin from the upper arm, fibulin-5 colocalized with the other elastic fibre components, while in the papillary dermis fibulin-5 showed candelabra-like structures perpendicular to the epidermis with an unstained area just beneath the epidermis, which was similar to that of elastin but not fibrillin-1. Fibulin-5 in the reticular dermis decreased and disappeared with age even in sun-protected skin from the thigh, abdomen and upper arm. In sun-exposed skin, fibulin-5 was extremely reduced in the dermis of cheek skin even from a 20-year-old man. UVB irradiation reduced fibulin-5, fibulin-2 and elastin markedly, moderately and weakly, respectively, compared with levels in control nontreated skin. Interestingly, the deposition of fibulin-5 was increased in solar elastosis, like that of other elastic fibre components.Conclusions  These results suggest that fibulin-5 is a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2005.06716.x
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