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  • 1985-1989  (5)
  • 1975-1979  (1)
  • 1
    Digitale Medien
    Digitale Medien
    A modification of the surface of the thin membranes of EVAL (ethylene vinylalcohol copolymer) by Langmuir-Blodgett films (1987)
    Springer
    Colloid & polymer science 265 (1987), S. 26-30 
    Details
    ISSN: 1435-1536
    Schlagwort(e): Ethylene vinylalcohol copolymer ; EVAL multilayer ; hemo-dialysis ; rejection of albumin ; permeability
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Maschinenbau
    Notizen: Abstract The surface modification of the membrane as an artificial kidney made of two kinds of ethylene-vinylalcohol copolymers with 32 and 44 mol % contents of ethylene group (EVAL) have been studied by depositing the polymer monolayer on the membrane surface using the Langmuir-Blodgett technique. The permeability to PSS (physiological salt solution) and albumin rejection of the membranes were measured against the number of multilayers. The UFR (ultrafiltration rate) of PSS containing albumin decreased with the increase of the built up layers up to 2 layers and showed constant values from 3 to 10 layers of LB films. On the other hand, albumin rejection increased with the increase of built up layers. Albumin rejection for these deposited membranes of multilayer of EVAL-32 showed 21 times effectiveness more than that of ordinary membrane and 16 times for EVAL-44. Modification of the membrane has been performed by such a network structure formed by the built-up films.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01422659
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Scale-up of hydrophobic interaction chromatography for purification of antitumor antibiotic SN-07 (1989)
    Springer
    Bioprocess and biosystems engineering 4 (1989), S. 163-167 
    Details
    ISSN: 1432-0797
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Abstract Scale-up of hydrophobic interaction chromatography for purification of SN-07 was studied. The height equivalent to a theoretical plate of the adsorbent gel (Sepabeads FP-PH 12) was kept constant for various superficial liquid velocities and column diameters. The efficiency of purification was also constant for the Sepabeads FP-PH 12 columns ranging from 16 mm to 113 mm in inner diameter. Effects of the ligand concentration on the adsorption capacity were also studied, and the adsorption capacity increased with an increase in the ligand concentration. These effects resulted in decreasing the required amount of salt to purify SN-07.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00369395
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  • 3
    Digitale Medien
    Digitale Medien
    Immunohistochemical evidence of serotoninergic regulation of vasoactive intestinal polypeptide (VIP) in the rat suprachiasmatic nucleus (1987)
    Springer
    Histochemistry and cell biology 86 (1987), S. 573-578 
    Details
    ISSN: 1432-119X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary By applying a double-immunolabeling technique to preembedded tissue preparations, we demonstrated the existence of serotoninergic innervation to neurons containing vasoactive intestinal polypeptide (VIP) in the rat suprachiasmatic nucleus (SCN). Immunoreactivity for serotonin and VIP was revealed by the presence of diaminobenzidine (DAB) reaction products and silver-intensified DAB reaction products, respectively; in a further stage, the silver grains were substituted with gold particles. DAB reaction products were precipitated on the surface of vesicular structures, while gold particles were scattered densities. Serotoninergic axons were numerous and closely packed together, occasionally forming synaptic junctions with gold-labeled VIP-containing neurons. At these synaptic junctions, small vesicular structures accumulated to form a coat under the presynaptie membrane, and the postsynaptic membrane was lined with a homogeneous accumulation of fine deposits. This postsynaptic apparatus varied in appearance; some parts were flat and thin, while others were of irregular thickness. Serotoninergic fibers also formed synaptic junctions with unidentified neurons, in which postsynaptic membrane specialization was also observable. As VIP-containing neurons are known to be synapsed by somatostatin (SRIH)-containing neurons, their regulation must involve both serotonin and SRIH at least.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00489549
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  • 4
    Digitale Medien
    Digitale Medien
    Immunoelectron microscopic observations of hypothalamic TRH-containing neurons in rats (1986)
    Springer
    Experimental brain research 63 (1986), S. 495-504 
    Details
    ISSN: 1432-1106
    Schlagwort(e): TRH-neurons ; Immunoelectron microscopy ; Synapse ; Hypothalamus ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Immunoreactive TRH-containing neurons and their synaptic associations were studied electron microscopically in the paraventricular nucleus (PVN) and dorsomedial nucleus (DMH) of the rat hypothalamus. In propylthiouracil (PTU)-treated rats, the immunoreactive cell bodies in the PVN appeared to be activated, showing a hypertrophic perikaryon, well developed Golgi bodies and numerous secretory granules. No such alterations were evident in the TRH neurons in the DMH. These findings suggest that the PVN-TRH neurons are involved in the hypothalamic-hypophysial-thyroid axis. Further, it was shown that unlabeled nerve terminals containing small and large clear vesicles make synaptic contacts with the TRH perikarya in the PVN. Thus it is likely that PVN-TRH neurons are regulated both by thyroid hormones and by other neuronal signals. In the DMH, unlabeled nerve terminals containing small and large clear vesicles, and immunoreactive terminals form synapses with TRH neurons. Thus the DMH-TRH neurons may be under dual neuronal control. It was further noted that in the DMH and PVN, TRH nerve terminals make synaptic contacts with other unlabeled neurons. It is evident that TRH acts as a neurotransmitter or neuromodulator, although the origin of TRH terminals should be elucidated.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00237473
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  • 5
    Digitale Medien
    Digitale Medien
    Traumatic arterio-venous fistula with false aneurysm in neurofibromatosis (1988)
    Springer
    Neuroradiology 30 (1988), S. 88-88 
    Details
    ISSN: 1432-1920
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00341955
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  • 6
    Digitale Medien
    Digitale Medien
    A study on tension signs in lumbar disc hernia (1979)
    Springer
    International orthopaedics 3 (1979), S. 225-228 
    Details
    ISSN: 1432-5195
    Schlagwort(e): Spine ; Lumbar spine ; Disc hernia ; Tension signs
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé Les lames des dernières vertèbres lombaires ont été réséquées sur cinq cadavres dans les quatre heures suivant la mort. Un court tube de caoutchouc a été inséré entre les racines nerveuses et le disque lombaire; la tension a été ensuite enregistrée grâce à des capteurs de pression transistorisés. Les stress angulaires exercés sur les racines lombaires lors de la recherche des signes de tension correspondent aux résultats fournis par l'expérience clinique.
    Notizen: Summary The laminae were removed from the lower lumbar spines of five cadavers within four hours of death. A short length of rubber tube was inserted between the nerve roots and the lumbar disc and the tension monitored using semiconductor pressure transducers. The angulatory stresses exerted on the lumbar nerve roots during tension sign tests were found to correspond to clinical experience.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00265716
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