ISSN:
1432-2099
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Conclusions The model of two initial radiation - induced radical components in oriented fibers of DNA,T − andG + [1], should be amended, for 5-halouracil substituted DNA by the finding that the primary anion is formed on the 5-halouracil base specifically but differentiates, depending on the halogen substituent, intoπ*- andσ*-forms. The occurrence of the latter appears, from theoretical calculations, to be connected with a C-halogen bond elongation. The DNA matrix apparently allows for this whereas in the corresponding single crystals of 5-bromodeoxyuridine [1] or 5-iododeoxyuridine [4] the crystal packing prevents the elongation thus allowing forπ*-anion formation only.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01221223
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