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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 25 (1986), S. 2126-2134 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Surgical and radiologic anatomy 9 (1987), S. 27-35 
    ISSN: 1279-8517
    Keywords: Hip joint ; Surgical approach ; Transgluteal approach ; M gluteus medius
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Afin de préciser les modalités techniques de la voie d'abord dite transglutéale de la hanche, les auteurs ont étudié la structure et la topographie des éléments anatomiques interposés sur cette voie d'accès. Les muscles moyen fessier, petit fessier et vaste latéral sont en continuité anatomique par leurs fibres tendineuses. Le muscle petit fessier s'enroule sur le versant crânial puis latéro-ventral de la capsule à laquelle il s'amarre par des tractus fibreux et des expansions tendineuses, son tendon terminal échange des fibres avec la partie ventrale du tendon du moyen fessier et se met en continuité avec les fibres tendineuses superficielles de la partie ventrale du vaste latéral. La zone de jonction tendineuse des trois formations musculaires est étroitement amarrée au versant ventral du grand trochanter. Le pédicule vasculo-nerveux caudal de l'espace moyen fessier-vaste latéral est situé à une distance de 3 à 5 cm du sommet du grand trochanter. Les déductions chirurgicales pratiques sont présentées, concernant en particulier les modalités de préparation de la berge ventrale de l'incision transglutéale, l'exposition de la capsule, et la préservation du pédicule vasculo-nerveux, avec référence aux notions exposées dans des travaux déjà publiés ailleurs.
    Notes: Summary In order to define the technical modalities of the so-called transgluteal approach to the hip, the authors studied the structure and topography of the anatomic features encountered in this approach. The gluteus medius, gluteus minimus and vastus lateralis muscles are anatomically continuous by way of their tendinous fibers. The gluteus minimus muscle winds over the cranial and then anterolateral aspect of the capsule, to which it is bound by fibrous tracts and tendinous expansions; its terminal tendon blends its fibers with the anterior part of the tendon of the gluteus medius and enters into continuity with the superficial tendinous fibers of the anterior part of the vastus lateralis. The zone of junction of the three muscle structures is closely bound to the anterior aspect of greater trochanter. The caudal neurovascular trunk of the space between the gluteus medius and vastus lateralis is situated at a distance of 3 to 5 cm from the greater trochanter. The practical surgical implications are discussed, particularly as regards the methods of dissecting the anterior margin of the transgluteal incision, exposure of the capsule and preservation of the neurovascular pedicle, with reference to concepts published previously in studies elswhere.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 45 (1989), S. 352-355 
    ISSN: 1420-9071
    Keywords: Cytoprotection ; cyclosporin ; endocrine pancreas ; insulin-secretion ; electron microscopy ; prostaglandin analogue ; rioprostil
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Cyclosporin A toxicity on pancreatic B-cells and its prevention by rioprostil, a prostaglandin E1 analogue, were studied in the model of the isolated perfused pancreas of rats treated with both compounds for 8 days. At toxic doses of cyclosporin (10 and 20 mg/kg b.wt), the B-cells showed severe hydropic degeneration of the endoplasmatic reticulum and slight degranulation of the B-cells. Accordingly, the insulin secretion was markedly impaired. Administration of rioprostil ameliorated the insulin secretion significantly, but not the ultrastructural changes. At therapeutic levels of cyclosporin (5 mg/kg b.wt), the hydropic degeneration and the drop in insulin secretion were completely prevented by rioprostil. This observation might have therapeutic implications in the treatment of patients, in particular those undergoing pancreatic transplantation.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 65 (1987), S. 949-954 
    ISSN: 1432-1440
    Keywords: Insulin receptor ; Insulin resistance ; Insulin action
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Clinical data on insulin binding to blood cells contribute to our present knowledge of insulin resistance. Binding data have been frequently presented to indicate alterations in insulin action. It is now evident that insulin binding data are of limited value for our understanding of insulin resistance. This is mainly due to the tissue-specific binding of insulin as well as the “pleiotypic” nature of insulin action. As insulin action is determined at (a) the “pre-”receptor level, (b) the receptor, and/or (c) different postbinding sites, it is unlikely that receptor data alone can explain defective insulin action. As knowledge of the molecular biology of insulin receptor morphology and function as well as of the action of insulin on intermediary metabolism increases, clinicians should not be further overloaded with binding data. Nevertheless, binding data on blood cells may be still of some value in investigating patients with severe insulin resistance due to genetic disorders of the insulin receptor or insulin receptor autoantibodies.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1440
    Keywords: Diabetes ; Fructosamine ; Non-enzymatic protein glycosylation ; Glycated hemoglobin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary For some years the glycosylated plasma proteins, the so-called fructosamines, have been used for the evaluation of metabolic control in diabetic patients. We studied the usefulness of fructosamine as an intermediate parameter in the control of diabetes and we also corrected fructosamine for serum protein. Furthermore, the dependence on daily times and amounts of food intake were examined for fructosamine alone as well as for protein-corrected fructosamine. Both parameters showed a statistically significant correlation with HbA1C (r=0,7;P〈0,001). Changes in the metabolic state of the diabetic patients were reflected more rapidly by both these parameters than by HbA1C. While the correction of fructosamine for serum protein eliminated its postprandial increase in the diabetic patients, circadian variation remained unchanged.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Experiments in fluids 3 (1985), S. 17-23 
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The temperature field of starting thermal plumes were measured in a rotating annulus with various rotation rates and buoyancies. The experiments revealed many details of the internal structure of these convective phenomena and also significant horizontal displacements from their source. Measurements show an increase in the maximum temperature observed in the thermal caps with increasing rotation and a more rapid cooling of the buoyancy source.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0789
    Keywords: Decomposition ; Mesh bag ; Nitrogen mineralization ; 15N
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary In two field experiments, plant materials labelled with 15N were buried separately within mesh bags in soil, which was subsequently sown with barley. In the first experiment, different parts of white clover (Trifolium repens), red clover (T. pratense), subterranean clover (T. subterraneum), field bean (Vicia faba), and timothy (Phleum pratense) were used, and in the second, parts of subterranean clover of different maturity. The plant materials were analysed for their initial concentrations of total N, 15N, C, ethanol-soluble compounds, starch, hemicellulose, cellulose, lignin, and ash. After the barley had been harvested, the bags were collected and analysed for their total N and 15N. In the first experiment the release of N was highest from white clover stems + petioles (86%) and lowest from field bean roots (20%). In stepwise regression analysis, the release of N was explained best by the initial concentrations of lignin, cellulose, hemicellulose, and N (listed according to decreasing partial correlations). Although the C/N ratio of the plant materials varied widely (11–46), statistically the release of N was not significantly correlated with this variable. The results of the second experiment using subterranean clover of different maturity confirmed those of the first experiment.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 71 (1988), S. 252-261 
    ISSN: 1432-1106
    Keywords: Fluorescent tracers ; Brainstem ; Auditory ; Efferent system ; Gerbils
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The distribution and the projection patterns of olivo-cochlear neurons (OCN) was studied in three species of gerbils (Meriones unguiculatus, Meriones tristrami, Pachyuromys duprasi) using fluorescent tracers (Fast blue, Diamidino yellow) in double labeling experiments. In all gerbil species up to 1600 retrogradely labeled neurons were found in the superior olivary complex. Small OCN were located inside or at the margins of the lateral superior olive. A second set of larger OCN was seen bilaterally in the periolivary region of the superior olivary complex forming an independent cell population within the trapezoid body. The exact locations of small and large OCN varied among the particular species. Quantitative results suggested that a gradual loss of large OCN might be a general feature of species with highly specialized frequency selectivity.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1076
    Keywords: Osteogenesis imperfecta ; Cardiac malformation ; Kidney stones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined 58 children aged 1–16 years with various forms of osteogenesis imperfecta (OI). Congenital cardiac malformations were diagnosed in 4 children (valvular aortic stenosis, 2 with atrial septal defect II, Fallot Tetralogy). Two additional children developed holosystolic mitral valve prolapse and regurgitation. Children suffering from a severe clinical course (type III according to the Sillence classification) showed aortic root dilatation (28%) and increased septal (40%) and posterior left ventricular wall thickening (68%) on initial evaluation. All three parameters were significantly correlated to body surface area. Kidney stones and renal papillary calcifications were detected in 4 children. Cardiovascular abnormalities and nephrolithiasis may be important extraskeletal manifestations of childhood OI.
    Type of Medium: Electronic Resource
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