ISSN:
1432-1440
Schlagwort(e):
Guillain-Barré syndrome (GBS)
;
Herpes simplex virus (HSV)-IgM antibodies
;
Immunohistology
;
Plasma exchange
;
Immunosuppression
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary Herpes simplex virus (HSV) has been associated with various neurological disorders. In contrast, HSV infection is very rarely found in acute polyneuroradiculitis. In this report, a patient is described with a severe course of Guillain-Barré syndrome (GBS). HSV IgM-specific antibodies and a rise of complement-fixation antibodies were detected. During the acute phase of neurologic syndrome, a nerve biopsy showed myelin damage and IgM deposits on the inner layer of the perineurium. Plasma exchange, in combination with immunosuppression, was successfully applied as a treatment in the relapsing course of GBS. Finally, after recovery, HSV-specific IgM antibodies disappeared.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01731495
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