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  • 1
    Electronic Resource
    Electronic Resource
    Paraneoplastic brainstem encephalitis with acute dystonia and central hypoventilation (1982)
    Springer
    Journal of neurology 227 (1982), S. 229-238 
    Details
    ISSN: 1432-1459
    Keywords: Paraneoplastic syndromes ; Carcinoma, bronchogenic ; Encephalitis ; Hypoventilation ; Dystonia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei einem 55 Jahre alten Patienten mit bekanntem Bronchialcarcinom entwickelten sich dystone Bewegungsstörungen des rechten Armes, Schluckbeschwerden und eine progrediente Kieferklemme. Hinzu kamen horizontale Blickparese, ataktische Störungen und Verminderung der Vibrationsempfindung. Vor dem Tode bestand neben kompletter Ophthalmoplegie und nahezu vollständiger Kiefersperre eine zentrale Hypoventilation. Die neuropathologische Untersuchung zeigte das Vorliegen von Hirnstammencephalitis, Ganglioradikuloneuritis, Hinterstrangdegeneration des Rückenmarkes und geringem Purkinje-Zell-Ausfall im Kleinhirn. Die Veränderungen werden als kombiniertes paraneoplastisches Syndrom erklärt. Die klinisch imponierenden Symptome der zentralen Hypoventilation und dystonen Bewegungsstörung werden beschrieben. Mögliche morphologische Korrelate werden diskutiert.
    Notes: Summary A 55-year-old patient with known lung cancer was admitted with dystonia of the right arm, lockjaw, horizontal gaze palsy and dysphagia. Prior to death total ophthalmoplegia and central hypoventilation developed. Postmortem examination showed brainstem encephalitis, gangioradiculoneuritis, posterior column degeneration and loss of cerebellar Purkinje cells. These changes are considered to constitute a combined paraneoplastic syndrome. The dystonic movement disorder and central hypoventilation and their possible morphologic correlates are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313390
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  • 2
    Electronic Resource
    Electronic Resource
    Rise in blood pressure increases the release of endogenous catecholamines in the anterior hypothalamus of the cat (1980)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 310 (1980), S. 237-240 
    Details
    ISSN: 1432-1912
    Keywords: Hypothalamus ; Arterial Blood Pressure ; Catecholamines ; Splanchnic Nerve ; Rise in Blood Pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In anaesthetized cats, anterior and posterior hypothalamic areas were simultaneously superfused with artificial CSF using two push-pull cannulae. The rates of release of endogenous catecholamines were determined in the superfusates which were continuously collected in periods of 10 seconds. In both areas, the rate of release of dopamine was higher than the rates of release of noradrenaline and adrenaline. Electrical stimulation of the splanchnic nerve elicited a rise in the arterial blood pressure and increased the rates of release of noradrenaline, adrenaline and dopamine in the anterior hypothalamic area. The rates of release of the catecholamines in the posterior hypothalamic area were not influenced by the pressor response to stimulation of the splanchnic nerve. Transection of the brain caudal to the hypothalamus reduced the rates of release of the catecholamines in the anterior hypothalamus and abolished the releasing effect of the stimulation of the splanchnic nerve. The results indicate that acute rise in blood pressure activates catecholamine cell bodies in the lower brain stem, which in turn stimulate the anterior hypothalamus to counteract the pressor response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00499916
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of short-lasting and long-lasting blood pressure changes on the release of endogenous catecholamines in the hypothalamus of the conscious, freely moving rabbit (1983)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 322 (1983), S. 203-209 
    Details
    ISSN: 1432-1912
    Keywords: Endogenous catecholamines ; Push-pull cannula ; Rhythmic release ; Blood pressure ; Hypothalamus ; Conscious rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In anaesthetized rabbits guide cannulae were stereotaxically inserted into the anterior hypothalamic area and into the posterior hypothalamic nucleus. Additionally, catheters were inserted into the carotid artery and the jugular vein. Some days after the operation push-pull cannulae were inserted through the guide cannulae into the hypothalamic regions of the conscious, freely moving animal. The areas were superfused with artificial CSF and the release of the endogenous catecholamines dopamine, noradrenaline and adrenaline was determined in the superfusates. In the two hypothalamic regions the resting release of the catecholamines rhythmically varied with time at approximately 70 min cycles. A rise in blood pressure induced by the intravenous injection of noradrenaline or tramazoline enhanced the rates of release of the catecholamines in the anterior hypothalamic area. A fall of blood pressure elicited by the intravenous injection of nitroprusside or chlorisondamine decreased the release of the catecholamines in this hypothalamic area. The changes in blood pressure coincided with the changes in the rates of release of the catecholamines in the anterior hypothalamic area. These and previous results concerning changes in the release of endogenous catecholamines in the posterior hypothalamic nucleus also indicate that in the conscious, freely moving rabbit changes in blood pressure lead to counteracting alterations in the release of catecholamines in the two hypothalamic regions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00500766
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  • 4
    Electronic Resource
    Electronic Resource
    In vivo release by histamine agonists and antagonists of endogenous catecholamines in the cat hypothalamus (1984)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 326 (1984), S. 116-123 
    Details
    ISSN: 1432-1912
    Keywords: Hypothalamus ; Push-pull cannula ; Catecholamines ; Histamine ; Histamine receptor agonists ; Histamine receptor antagonists
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The posterior hypothalamus of anaesthetized cats was superfused through a push-pull cannula with histamine agonists and antagonists and the release of endogenous catecholamines was determined in the superfusate. Hypothalamic superfusion with histamine, 2-methylhistamine (H1-agonist), dimaprit (H2-agonist) or metiamide (H2-antagonist) enhanced the release of the catecholamines dopamine, noradrenaline and adrenaline. The releasing effects of these substances depended on the presence of calcium ions. Superfusion with 2-pyridylethylamine (H1-agonist) was virtually ineffective, while superfusion with 2-thiazolethylamine (H1-agonist) enhanced the rate of release of noradrenaline and adrenaline without influencing the release of dopamine. Superfusion with mepyramine (H1-antagonist) inhibited the release of noradrenaline and adrenaline without affecting the release of dopamine. Hypothalamic superfusion with a concentration of procaine which was equi-anaesthetic to that of mepyramine was ineffective. Ranitidine (H2-antagonist) did not alter the rates of release of the catecholamines. The releasing effect of histamine was inhibited on hypothalamic superfusion with mepyramine and ranitidine. Ranitidine also inhibited the releasing effects of dimaprit and 2-methylhistamine thus indicating that the releasing action of the latter compound was mainly due to stimulation of H2-receptors. These data suggest that blockade of H1-receptors of the posterior hypothalamus reduces the release of noradrenaline and adrenaline, while stimulation of H1-receptors seems to increase the rates of release of these two catecholamines. Stimulation of H2-receptors enhances the release of all three catecholamines. Thus, dopaminergic neurones of the hypothalamus seem to possess H2-receptors, while noradrenergic and adrenergic neurones possess H1- and H2-receptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00517307
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  • 5
    Electronic Resource
    Electronic Resource
    Total cross section for hadron production bye + e − annihilation between 9.4 and 9.5 GeV (1980)
    Springer
    The European physical journal 6 (1980), S. 125-129 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The total cross section fore + e − annihilation into hadrons for center of mass energies from 9.4 to 9.5 GeV has been measured with the nonmagnetic DESY-Heidelberg detector at DORIS. A value ofR=σhad/σµµ=3.8±0.7 for the continuum region around the Υ (9.46) resonance has been determined. The ratioΓ ee Γ had/Γ tot of electronic, hadronic and total widths has been reevaluated to be (1.00±0.23) keV for the Υ resonance and (0.37±0.16) keV for the Υ′. In addition, a search for directly produced pohotons from Υ decays of the type Υ→γ+gluon+gluon has been performed. The Υ decay into muon pairs has also been searched for.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01588838
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  • 6
    Electronic Resource
    Electronic Resource
    Study of the charge-exchange reactions $$\pi ^ - p \to (\pi ^0 ,\eta ,\eta \prime )n$$ at 63 GeV (1981)
    Springer
    The European physical journal 8 (1981), S. 95-100 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Total and differential cross-sections have been measured for the reactions $$\pi ^ - p \to (\pi ^0 ,\eta ,\eta \prime )n$$ . The results agree with those of two experiments carried out in the same energy range, apart from measurements at high |t| for the charge-exchange reaction π− p→π0 n. The latter indicate a deviation from the prediction of a single Regge-pole model with linear trajectories at high incident momentum and high momentum transfer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01547872
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  • 7
    Electronic Resource
    Electronic Resource
    Evidence for a non- $$q\bar q$$ tensor meson at 1,410 MeV produced in the reaction π− p→K s 0 K s 0 n at 63 GeV (1984)
    Springer
    The European physical journal 23 (1984), S. 339-347 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present an analysis of theK s 0 K s 0 system produced in the reaction π− p→K s 0 K s 0 n at 63 GeV based on ∼700 events in the kinematical region of |t|〈0.5 GeV2. We concentrate on masses between 1,200 and 1,600 MeV where a double maximum structure is observed. Performing an amplitude analysis in this mass interval we find thatS,D 0 andD + waves contribute to the mass spectrum at approximately equal strength. The peaks are attributed to spin 2 waves. However, we failed to explained them by interferingf(1270),A 2(1310) andf′(1520) resonances alone. While the first peak can be associated withf(1270)−A 2(1310) production, an additional tensor meson is needed with mass of ∼1410 MeV and a narrow width for a description of the second one. The analysis as well as the energy dependence deduced from some publishedK s 0 K s 0 mass spectra suggests this object to be dominantly produced by a natural parity exchange. Because the 2++ $$q\bar q$$ nonet is already complete the nature of the new tensor meson is an open question.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01572657
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