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  • Digitale Medien  (13)
  • 1980-1984  (6)
  • 1975-1979  (7)
Materialart
  • Digitale Medien  (13)
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  • 1
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    R & D management 14 (1984), S. 0 
    ISSN: 1467-9310
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Wirtschaftswissenschaften
    Notizen: This paper is based on a critical review of the proceedings of the Second International Conference on Interdisciplinary Research held in 1981 in Manchester, England. Two sets of issues important for the management of collaborative research are identified. One is the need to remove ambiguities from the meanings of commonly used terminology, for which more precise definitions are proposed. Cross-disciplinary is used to describe only the nature of the task; multi- and inter-disciplinary are seen as describing alternative organizational ways of executing it. Which way should be used depends objectively on the circumstances.The other set of issues is concerned with the effect institutional setting could have on the possibility of carrying out effective cross-disciplinary activity. Six different settings are identified and broad concepts of group dynamics are used to identify theoretical and practical problems and their possible solutions. The paper concludes with a survey of the practical implications for those managing cross-disciplinary research.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 98 (1978), S. 0 
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The frequency of two newly defined HLA antigens, HLA CT7 and DMA, was found to be greatly increased in patients with psoriasis. These two antigens and those previously found to be associated with the disease, B13, BW16 and BW17, frequently occurred together. The disease may be primarily associated with HLA DMA, or with the HLA haplotypes CT7-B13/W16/W17-DMA.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 8 (1977), S. 1-28 
    ISSN: 0066-4162
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 11 (1977), S. 0 
    ISSN: 1095-8649
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Notizen: Electrophoretic variation of Atlantic salmon NADP-isocitrate dehydrogenase in liver extracts of material from Ireland is interpreted in terms of two loci, IDH-A and IDH-B, coding for cytoplasmically-located isozymes. The IDH-A locus is polymorphic with qIDH-A1=0.18 and qIDH-A2=0.82. This polymorphism is of potential value for investigating the population genetics of the two races of Atlantic salmon in Ireland. An additional, monomorphic band which appears in heart extracts may be a mitochondrial enzyme coded by a third locus.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 43 (1978), S. 0 
    ISSN: 1750-3841
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The enzymatic solubilization of an insoluble alfalfa protein fraction was studied in a batch reactor and in a continuous flow semi-batch membrane reactor. The “white” cytoplasmic protein fraction obtained by heat precipitation was solubilized using the proteolytic enzyme trypsin. Batch studies were carried out at pH 7.7 with a trypsin to substrate ratio of 2 x 10m-3 (by weight). At 27, 37 and 47°C the hydrolysis reaction was found to be first-order in substrate concentration. The activation energy was 23.25 kcal. At 47°C the conversion level was 97% after 4 hr. For the membrane reactor system, the effects of the variables pH, temperature, substrate concentration, and trypsin to substrate ratio were evaluated with the aid of factorial design methods. The optimum operating conditions for the membrane reactor studies were 47°C at pH 7.7 with a trypsin to substrate ratio of 4 x 10-3 at a 0.5% solids concentration level. The hydrolysis process was enhanced if the reactor was operated in a washout mode prior to the addition of enzyme suggesting that soluble low molecular weight inhibitors were washed out of the reactor with the permeate. 55% of the total amount of insoluble starting material appeared as products in the permeate after 4 hr of operation under the conditions stated above.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Marine biology 78 (1984), S. 315-324 
    ISSN: 1432-1793
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Strings of moored sediment traps were deployed in a 150 m water column over a period covering the growth and collapse of the spring bloom (4 April–3 June 1976) in an area of the northern North Sea. The efficiency of collection of material in the moored traps was compared to collections in free-drifting traps in the same area of deployment. The ways in which the data from the trap collections may be interpreted was considered at some length and a best estimate of the flux of organic carbon and nitrogen to the sediment was made. For the period prior to the spring bloom (4–23 April) this flux was 50 mg C m−2 d−1 (about 20% of primary production). During the bloom (24 April–19 May) it was about 185 mg C m−2 d−1 (35% of production) and during early summer (20 May–3 June) it was 115 mg C m−2 d−1, about 25% of the overlying production. The organic carbon and nitrogen content of the material collected was measured and the material was examined microscopically. There was evidence of a large settlement of diatoms immediately after the spring bloom which was reflected in changes in the C:N and C:chlorophyll ratios of the material collected. This change in biochemical composition of the material may affect its nutritional quality and have a stimulatory effect on the growth and reproduction of the animals living in the sediment.
    Materialart: Digitale Medien
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    European biophysics journal 6 (1980), S. 235-251 
    ISSN: 1432-1017
    Schlagwort(e): Alcohols ; Induced photoreceptor noise ; Phototransduction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Physik
    Notizen: Abstract Intracellular potentials are recorded from photoreceptors in a superfused preparation of the retina of a locust compound eye. Chloral hydrate and alkyl alcohols induce a rapid, superfusing reversible depolarization of these photoreceptors when dissolved in the saline. Analysis of voltage noise accompanying depolarization by chloral hydrate suggests that depolarizing ionic pathways are opened briefly and randomly in time in the photoreceptor membranes. This conclusion is supported by measurements of the cell resistance and of voltage noise amplitude as a function of membrane potential. Replacement of superfusate sodium by choline reversibly reduces the effects of chloral hydrate, suggesting that the ionic pathways opened are permeable by sodium. The voltage noise induced by chloral hydrate is compared to that during depolarization by steady illumination of the same cell. As the illumination intensity is increased, the amplitude and the shape of the power spectrum of light-induced voltage noise approach those of drug-induced noise at the same depolarization level. The possibility that these phenomena represent alterations in the mechanism of phototransduction is discussed.
    Materialart: Digitale Medien
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  • 8
    ISSN: 1432-1203
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary We report an example of four generation familial retinoblastoma in which there are three distinct categories of RB gene expression: frank retinoblastoma, unilateral or bilateral; retinoma; and no visible evidence of retinal pathology other than normal degeneration with age. Two large sibships derived from matings informative for RB and EsD provide strong confirmatory evidence for tight linkage between these loci (P=0.0002), and thus assignment of RB to chromosome 13q14. There is a striking difference (P(2%) in RB penetrance between the two principal generations, which suggests that an additional epistatic, host-resistance gene may also be segregating within the family.
    Materialart: Digitale Medien
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  • 9
    ISSN: 1432-1211
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Tropical animal health and production 9 (1977), S. 37-45 
    ISSN: 1573-7438
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé Une Theilerie a pu être transmise à un jeune bovin par des nymphes d'Amblyomma cohaerens recueillies chez des buffles (Syncerus caffer) de la région de Mara au Kenya. Des macroschizontes ont été isolés dans les ganglions 12 jours après les piqûres de tiques et, par la suite, on les retrouve, mais en petit nombre, pendant trois jours. Les Macroschizontes, volumineux et renfermant de nombreux noyaux, diffèrent des autres schizontes de Theileries décrits antérieurement chez des bovins d'Afrique du Sud et d'Afrique de l'Est. Ils ressemblent aux macroschizontes deT. barnetti Brocklesby, 1965 du Buffle provenant également de la région de Mara. Des Piroplasmes qu'il est impossible de différencier deT. mutans one été trouvés dans le sang du bouvillon 61 jours après la piqûre des tiques. En utilisant un test d'immunofluorescence indirecte avec un antigène à base deT. mutans (Aitong) seule, on observe une montée significative du taux d'anticorps. Le parasite ne semble pas pathogène et peut être transmis par injection de sang périphérique à un veau préalablement splénectomisé. Bien que le parasite ait des affinités certaines à l'égard deT. barnetti et deT. mutans (Aitong) son identité exacte ne peut être précisée et d'autres essais de transmission expérimentale s'avèrent.
    Kurzfassung: Resumen Se colectaron larvas repletas, de Amblyomma cohaerens, del búfalo Africano (Syncerus caffer) en la región de Mara en Kenya. Estas como ninfas, al ser puestas en contacto con un novillo le transmitieron un parásito teilerial. Se detectaron macroesquizontes en los ganglios linfáticos regionales del animal, 12 días después del contacto con las garrapatas por tres días consecutivos con niveles bajos de parasitosis. Los macroesquizontes observados fueron de gran tamaño con numerosos núcleos, siendo morfológicamente distintos a cualquier otro esquizonte teilerial de los descritos en el Este y Oeste del continente Africano. Sin embargo, estos guardan cierto parecido con los macroesquizontes de T. barnetti, Brocklesby 1965, encontrados también en bufalo en la región de Mara, Kenya. Se detectaron piroplasmas morfológicamente indistinguibles de los de T. mutans en la sangre del novillo experimental, el día 61 después del contacto con las garrapatas. El novillo tuvo un aumento significativo en el título de anticuerpos solamente al antígeno piroplàsmico de T. mutans (Aitong), utilizando la prueba indirecta de anticuerpos fluorescentes. No hubo evidencia de la patogenicidad del parásito. La forma intraeritrocitica del parásito se pudo transmitir por pasaje directo de sangre bovina a un ternero esplenectomizado. A pesar de que el parásito mostró afinidad con T. barnetti y T. mutans (Aitong), conclusiones definitivas relacionadas con la identidad del parásito están sujetas a experimentaciones futuras.
    Notizen: Summary Amblyomma cohaerens nymphs, which had been collected as engorged larvae from African buffalo(Syncerus caffer) in the Mara region of Kenya, transmitted a theilerial parasite to a steer. Macroschizonts were detected in the regional lymph node of this steer 12 days after tick application and were subsequently detected for 3 days at low levels of parasitosis. The macroschizonts were large and had numerous nuclei, being morphologically unlike any other theilerial schizonts described previously from cattle in Eastern and Southern Africa, but they resembled the macroschizont ofT. barnetti Brocklesby 1965 from a buffalo also obtained in the Mara region. Piroplasms morphologically indistinguishable fromT. mutans were first detected in the blood of the steer on the sixty-first day after tick application. The steer showed a significant rise in antibody titre to onlyT. mutans (Aitong) piroplasm antigen, using the indirect fluorescent antibody test. There was no evidence that this parasite was pathogenic. The intraerythrocytic piroplasms proved to be blood-transmissible to a splenectomised calf. Although the parasite showed affinities toT. barnetti andT. mutans (Aitong) definite conclusions regarding its identity must await further transmission experiments.
    Materialart: Digitale Medien
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