ISSN:
1437-160X
Keywords:
Anti-rheumatoid
;
Drugs
;
Histidine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Groups of 15 patients with active rheumatoid arthritis were treated for 24 weeks with zinc sulphate, trien, captopril, clozic in two doses or a combination of d-penicillamine and hydroxychloroquine. Serum histidine levels were monitored along with measures of disease activity including C-reactive protein, plasma viscosity, articular index, grip strength and early morning stiffness. Zinc sulphate and trien were found to be ineffective while the other drugs all showed evidence of second-line action. Serum histidine was found to improve during successful therapy. The possible cause of low serum histidine and its response to therapy is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00541592
Permalink
