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  • 1980-1984  (2)
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Material
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Embolization and subsequent nephrectomy in metastatic renal cell carcinoma (1984)
    Springer
    World journal of urology 2 (1984), S. 122-126 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty-five patients with primary metastatic adenocarcinoma renis were treated by embolization and delayed nephrectomy. The objective of the study was to examine whether the natural history of the disease is influenced by this combined treatment. Most patients (19/25) had measurable metastatic lesions. No patient received additional therapy unless progression occurred. Embolization was mainly performed with Gelfoam and Gianturco coils. Complete remission of metastases was observed in 1 patient (still in remission after 36 months); stable disease in 6 patients (lasting between 14 and 31 months). Eighteen patients died after a median survival of 5.7 months (range 14 days to 11 months). No major complication related to the embolization procedure occurred. Angio-infarction followed by nephrectomy cannot be recommended for widespread use in patients with primary metastatic kidney carcinoma. The procedure may be tested in controlled clinical trials together with other treatment protocols, such as immunotherapy, infarction with radioactive particles, or chemoembolization. These approaches are experimental and therefore limited to institutions with sufficient experience.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00328091
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Phase II study of VP 16-213 (etoposide) in metastatic transitional cell urothelial cancer (1984)
    Springer
    Cancer chemotherapy and pharmacology 12 (1984), S. 64-65 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fifteen patients with measurable metastatic transitional cell bladder cancer were treated with VP 16-213 100 mg/m2 IV daily for 4 days, repeated every 3 weeks. There were no complete or partial (greater than 50% reduction in area, maintained for 6 weeks) responses. Two patients showed transient reduction by 50% in the area of measurable lesions, and a further five patients showed brief stabilisation of previously progressive disease. The treatment was well tolerated. In two patients, total WBC at the nadir fell below 1.0×109/l but without complications from infection. We conclude that VP 16-213 is inactive in metastatic transitional cell urothelial cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00255913
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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