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  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Ovarian arterial velocimetry, using real-time two-dimensional and pulsed Doppler ultrasound, was performed on 36 occasions in nine healthy women with regular menstrual cycles. The change in ovarian arterial compliance was based on the calculation of pulsatility index (PI). In the active ovary carrying a dominant follicle or corpus luteum, the PI in the early follicular phase (mean 6.97, SD 2.01) was significantly higher than that in the late follicular phase (mean 2.36, SD 0.31) (P〈0.001), and the PI in the early luteal phase (mean 0.68, SD 0.09) was significantly lower than that in the late follicular phase (P〈0.001). The PI in the late luteal phase (mean 0.93, SD 0.16) was significantly higher than that in the early luteal phase (P〈0.01). In the inactive ovary, no cyclical changes were seen in the values of PI. There was a significant difference between the values of PI in the active ovary and the inactive ovary in the late follicular, the early and the late luteal phases [2-36 (SD 0-31)] vs [6-29 (SD 1-02)], [0-68 (SD 0.09)] vs [6.18 (SD 1.33)], [0.93 (SD 0.16) vs [6-57 (SD 1.72)] (P〈0.001), respectively. Use of non-invasive Doppler ultrasound to study physiology of ovarian haemodynamics during the menstrual cycle is of great clinical relevance and paves the way for further investigations on sterility.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The characteristics of microchannel plates (MCPs) for x-ray detection have been investigated with continuous x-ray energy variation using synchrotron radiation in the XUV and soft x-ray region (from 60 to 600 eV). The current response data have shown x-ray absorption fine structure (EXAFS or XANES) near the oxygen K absorption edge as well as a jump structure near the silicon L edge; these structures are explained by the surface composition of channel walls (SiO2). The data show that the surface layer of a microchannel is essential for x-ray detection by MCPs in this energy range. The precise current response curve has been completed for the wide x-ray energy range from 0.06 to 82 keV combined with the previously reported data [Kondoh et al., Rev. Sci. Instrum. 59, 252 (1988); Cho et al., ibid. 59, 2453 (1988); Yamaguchi et al., ibid. 60, 368, 2307 (1989)].
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 65 (1994), S. 109-111 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: This work presents the first report on the growth mechanism of 123 films on metallic substrates with (200) oriented and partially a-b plane oriented polycrystalline yttria stabilized zirconia (YSZ) buffer layer, with and without a metallic underlayer coating used between the substrate and the buffer layer. The microstructure and grain morphology of 9- and 160-nm-thick films of Y1Ba2Cu3O7−δ (YBCO) were studied by scanning electron microscopy, scanning tunneling microscopy, and x-ray diffraction. Our studies reveal that YBCO films on c-axis oriented and partial a-b plane oriented YSZ buffer layers on metallic substrates, initially grow two dimensionally, with the elongated grains of ∼100 nm length, mostly aligned along the 〈200〉 axis of the YSZ, owing to the strong atom-substrate bonding. The thicker films, however, show three-dimensional terraced island growth with several turns of the screws, with the screw edges still along the 〈200〉 axis of YSZ. These terraced islands seem to coalesce in the film with the highest Jc value, ∼1×105 A/cm2.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 101 (1979), S. 5414-5415 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 38 (1993), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Intercellular adhesion molecule-1 (ICAM-1), a member of the immunoglobulin supergene family, is known to play an important role in inflammatory diseases. Using a previously developed enzyme-linked immunosorbent assay (ELISA) with two monoclonal antibodies (MoAbs) against human ICAM-1, levels of soluble ICAM-1 (sICAM-1) were measured in sera from patients with collagen diseases and in synovial fluids (SF) from patients with rheumatoid arthritis (RA). Although the results did not demonstrate that RA and other collagen diseases, as a group, had significantly higher levels of sICAM-1 in sera as compared with healthy controls, 21 of 138 cases (15%) with collagen diseases and 11 out of 57 patients (19%) with RA clearly showed higher levels of sICAM-1 in the sera. Comparisons between RA patients of radiological stages I and II and between stage I and other stages showed significantly higher levels of sICAM-1 in the sera of patients in the latter stages. RA patients with vasculitis and/or pneumonitis showed significantly higher levels of sICAM-1 than those without vasculitis or pneumonitis. Significant correlations were demonstrated between sICAM-1 and the factors IgG-RF, IgM-RF, erythrocyte sedimentation rate (ESR) and TNF-α in sera of RA patients. In addition, it was noted that the levels of sICAM-1 in SF were as high as those in the sera of patients with RA.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 275 (1978), S. 568-568 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] KIANG noticed1 the importance of the Kirkwood Gaps (particularly the Hecuba Gap) in contrast to Hilda Group in the asteroidal distribution problem, and presented a solution to this problem using a stability criterion inherited in Hill's equation which, he assumed, clarifies the difference between ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Mycopathologia 121 (1993), S. 65-75 
    ISSN: 1573-0832
    Keywords: Bones ; Candida albicans ; Experimental arthritis ; Radiography ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Sprague-Dawley rats were inoculated intravenously (i.v.) withCandida albicans, and limb joints showing signs ofCandida-induced arthritis were subjected to radiographic and histologic examination. New bone formation and bone resorption were morbidly enhanced in bones sampled from the arthritic joints. Sparsely distributed needle-shaped calcified deposits began to be formed on bony surfaces in parallel with the onset of joint swelling. The calcified deposits gradually became denser and then covered the bony surfaces almost entirely, giving rise to an exostosis-like profile. In addition to the new bone formation, bone resorption was also observed in regions adjacent to the sites of new bone formation, and punched-out bone lesions were produced. Eventually, severe deformation of joint bones due to new bone formation and bone resorption was evident. Reflecting these unusual radiographic changes, abundant osteoblasts and osteoclasts were demonstrated histologically in the bones. On the basis of these results, possible mechanisms for the induction of arthritis byCandida infection are discussed.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0428
    Keywords: Radioimmunoassay ; glycation ; HbA 1c glucose ; glucitollysine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A competitive radioimmunoassay for the quantitative determination of glycated haemoglobin was developed. The antiserum, obtained by immunizing guinea pigs with reduced glycated human albumin, was capable of identifying and quantitating the glucitollysine residues of glycated Hb after reduction with sodium borohydride. To simplify the sample preparation we introduced trichloroacetic acid precipitation to remove unreacted sodium borohydride instead of using dialysis or gel filtration. Using this procedure, our radioimmunoassay became relatively simple and provided satisfactory within- and between-run (1.3–2.8% and 1.9–5.4% coefficient of variation, respectively). The radioimmunoassay method was compared to the measurement of HbA 1c by high performance liquid chromatography which is the most widely used method for quantitating glycated Hb. For this purpose glycated Hb was measured in normal glucose tolerance, impaired glucose tolerance, and diabetes mellitus groups based on WHO criteria. Both assays were able to discriminate between the normal and diabetic groups. In addition, while the determination of glycated Hb by the radioimmunoassay method was able to clearly discriminate between the normal and impaired glucose tolerance groups, the determination of HbA 1c by the high performance liquid chromatography method failed to discriminate between these two groups. Moreover, 15 of the 20 impaired glucose tolerance patients exceeded the upper normal range (mean normal values + 2 SD) in radioimmunoassay. But all 20 patients with impaired glucose tolerance were within the upper normal range in HbA 1c values. These results demonstrate that the measurement of glycated Hb by radioimmunoassay is more sensitive than the measurement of HbA 1c by high performance liquid chromatography since it can discriminate between the normal and impaired glucose tolerance groups.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0428
    Keywords: IgE insulin antibody ; insulin allergy ; radioallergosorbent test ; highly purified insulin ; IgE ; monocomponent insulin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An in vitro method for detecting IgE insulin antibody using the principle of the radioallergosorbent test (RAST) is described. In six patients with insulin allergy, the RAST values were higher than in normal persons or insulin-treated diabetics without insulin-allergy. No differences were observed between normal persons and insulin-treated diabetics without insulin-allergy. Moreover, it was observed that in one patient treated with highlypurified insulin, there was a gradual decrease of RAST value parallel to the radioinsulin binding activity and clinical allergic symptoms. The RAST value of insulin is slightly inhibited by non-IgE antibodies and is, therefore, a semiquantitative value. However, the RAST is simple to perform and reproducible; It therefore is very useful in the detection of IgE insulin antibodies.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1420-9098
    Keywords: Aphid ; soldier investment ; gall ; tropics ; predation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The gall-forming aphidCerataphis fransseni produces soldiers that defend against predators. Soldiers are produced soon after colony foundation and the number of soldiers increases nonlinearly during colony growth. The number of soldiers scales to the square-root of the number of non-soldiers and linearly to the surface area of the gall. This suggests that soldiers are produced to defend an area, for example the perimeter of the colony or the surface of the gall, rather than individual aphids.
    Type of Medium: Electronic Resource
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