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  • 1
    Digitale Medien
    Digitale Medien
    TOPOGRAPHIC DETERMINATION OF ZINC IN HUMAN BRAIN BY ATOMIC ABSORPTION SPECTROPHOTOMETRY (1968)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 15 (1968), S. 0 
    Details
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Atomic absorption spectroscopy was used for measuring the zinc content, in ppb (μg/1), of brain tissue. A new method for determining the correction factor of atomic absorption interference is described.Measurements of the zinc content of twenty-four regions of adult human brains showed the maximum zinc content in resistent sector and endplate of the Amnion's horn, corroborating the histochemical data. The distribution of zinc in other regions was relatively uniform, but white matter showed lower values than gray matter. The zinc content of seventeen regions of human newborn brains was below that in adult brains, for all regions. The blood content of brain tissue contributed only insignificantly to its zinc content.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1471-4159.1968.tb08967.x
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  • 2
    Digitale Medien
    Digitale Medien
    Residual lesions of cerebral fat embolism (1977)
    Springer
    Journal of neurology 216 (1977), S. 227-233 
    Details
    ISSN: 1432-1459
    Schlagwort(e): Atrophy of white matter ; Cerebral fat embolism ; Coma, posttraumatic ; Dementia, posttraumatic ; Demyelination ; Residual lesions of cerebral fat embolism ; Ventricular enlargement
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Ein Fall von Spätläsionen nach massiver zerebraler Fettembolie zeigt zahlreiche fleckförmige Nekrosen und Zonen von Demyelinisierung der weißen Substanz der Großhirn- und Kleinhirnhemisphären und des Hirnstammes. Auf die Bedeutung dieser Läsionen für die Entstehung eines posttraumatischen Coma oder posttraumatischen Demenz wird hingewiesen.
    Notizen: Summary Necropsy findings of a case which survived for three months after massive cerebral fat embolism are presented. The lesions are charcterized by numerous patchy necroses and areas of demyelination in the white matter of cerebral and cerebellar hemispheres and brain stem, accompanied by atrophy of white matter and ventricular enlargement. Attention is drawn to the significance of these lesions for posttraumatic coma or dementia.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00314047
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  • 3
    Digitale Medien
    Digitale Medien
    Striato-nigral astrocytic melanization (1979)
    Springer
    Journal of neurology 220 (1979), S. 149-156 
    Details
    ISSN: 1432-1459
    Schlagwort(e): Melanin ; Astrocytic melanization ; Striato-nigral degeneration ; Catecholamine metabolism
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Bericht über 2 nicht verwandte Patientinnen, die eine abnormale Pigmentierung des Striatum und der Substantia nigra zeigten. Beide litten an debilitierenden Gelenkerkrankungen, aber hatten keine Geschichte neurologischer Symptomatik. Das abnormale Pigment fand sich in Astrocyten und hatte die histochemischen Eigenschaften und die Feinstruktur von Melanin. Die Veränderungen weisen auf eine Störung des Katecholaminstoff-wechsels hin, wobei offen bleibt, of dieselbe endogen ist oder auf unbekannten exogenen Faktoren beruht.
    Notizen: Summary Abnormal pigmentation was found in the striatum, pallidum and substantia nigra of two unrelated patients. Both had suffered from debilitating joint disease; there was no evidence of a progressive neurologic disorder. The pigment was localized in astrocytes and had the histochemical and electron microscopic features of melanin. The tissue changes suggest an anomaly of catecholamine metabolism either endogenous or induced by a still unknown exogenous factor.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00705533
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  • 4
    Digitale Medien
    Digitale Medien
    Fine structure of myomedulloblastoma (1977)
    Springer
    Acta neuropathologica 37 (1977), S. 43-48 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Myomedulloblastoma ; Myoblastoma ; Medulloblastoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Electronmicroscopic studies in a case of myomedulloblastoma support the concept that the medulloblastoma and the myoblastoma component of the tumor derive from different cell lines. The myoblastoma component shows bundles of myogenic elements, whereby quite undifferentiated cells lacking myofilaments are tightly attached to differentiated elements having well organized myofilaments. These bundles are encompassed by a common basement membrane, and their cells are joined by junctions, helping the identification of the undifferentiated elements. No comparable structures were seen in the medulloblastoma component. The fine structure of the myoblastoma is reminiscent of aspects of normal fetal development of skeletal muscle.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00684539
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  • 5
    Digitale Medien
    Digitale Medien
    A quantitative study of the composition of cerebellar cortical dysplasias (1979)
    Springer
    Acta neuropathologica 47 (1979), S. 67-70 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Cerebellar cortical dysplasia ; Malformations ; Histometry ; Fetal cell migration ; Cerebellar development
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The areas of molecular and granular layers in four large cerebellar cortical dysplasias were measured with the planimeter and the Purkinje cells were counted. There was a relative deficit of molecular layer and a still greater deficit of Purkinje cells in three of the four dysplasias. The fourth one had normal numbers of Purkinje cells per molecular layer and a relative deficit of granular layer. These abnormal proportions in the composition of a dysplasia may relate to the timing of its origin.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00698275
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  • 6
    Digitale Medien
    Digitale Medien
    Distribution of a catecholamine-binding mechanism in rat brain (1967)
    Springer
    Histochemistry and cell biology 9 (1967), S. 126-135 
    Details
    ISSN: 1432-119X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The existence of characteristic regional differences in the binding capacity of tissue for catecholamines was demonstrated by incubating sections of rat brain with tritiated norepinephrine or epinephrine or dopamine, and by radioautography. Microscopically, catecholamine binding occurred diffusely in the neuropil, or in pericellular aggregates upon nerve cells, in a pattern highly suggestive of synaptic buttons. A neuroanatomical account of the regional distribution patterns of norepinephrine binding in rat brain showed similarity to the known regional distribution of norepinephrine. However, there were quantitative and qualitative differences between the distribution of the binding mechanism and that of norepinephrine. Minor differences were found between the binding of norepinephrine and epinephrine; little binding occurred for dopamine. The binding mechanism was not facilitated by ATP, and was resistant to reserpine.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00305856
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  • 7
    Digitale Medien
    Digitale Medien
    Dural involvement in rheumatoid arthritis (1978)
    Springer
    Acta neuropathologica 42 (1978), S. 65-66 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Dura ; Rheumatic disease ; Rheumatoid arthritis ; Extra-articular manifestation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Involvement of the cranial dura in rheumatoid arthritis is rate; a new case of this complication is added to the four recorded instances. Dural involvement in rheumatoid arthritis may occur in the absence of other rheumatoid lesions of the CNS; it appears to take a clinically uneventful course and does not seem to represent a factor predisposing to the development of chronic subdural hematoma.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01273270
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  • 8
    Digitale Medien
    Digitale Medien
    Postencephalitic porencephaly, hydranencephaly or polymicrogyria. A review (1978)
    Springer
    Acta neuropathologica 43 (1978), S. 161-168 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Porencephaly ; Hydranencephaly polymicrogyria ; Encephalitis ; Toxoplasma cytomegalovirus ; Cortical dysplasias
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Twenty necropsy cases of the association of fetal encephalitis with porencephaly, hydranencephaly or polymicrogyria were reviewed including 5 from the authors' material. The latter include a basket brain, a porencephalic necrosis of recent date and a polymicrogyria in the formative state. The supratentorial lesions are often associated with cerebellar cortical dysplasias. The pathogenetic interdependence of encephalitis and hemispheric defects or malformation is discussed. Examples are given in which the infection appears to be secondary to a pre-existent hemispheric lesion. For others the hemispheric lesions appear to be secondary to encephalitis. In these the encephalitis may produce secondary lesions by a variety of pathogenetic mechanisms.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00685011
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  • 9
    Digitale Medien
    Digitale Medien
    Surface lesions of corpus callosum (1968)
    Springer
    Acta neuropathologica 10 (1968), S. 151-158 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Corpus callosum ; Brain injury ; Traumatic lesion ; Marchiafava-Bignami-disease ; Demyelination ; Pressure of arteries
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Oberflächliche Balkenläsionen werden beschrieben, die bisher offensichtlich nicht im Schrifttum aufscheinen. Sie wurden in 17 von 168 laufend untersuchten Gehirnen angetroffen. Beziehungen zu klinischen Symptomen oder den Körperobduktionsbefunden lagen nicht vor. Die Morphologie und Beziehungen dieser Läsionen zu den Nachbarstrukturen lassen sie als eine Folge mechanischer Balkenschädigung interpretieren, doch ist ihr genauer Entstehungsmechanismus bisher ungeklärt.
    Notizen: Summary Surface lesions of the corpus callosum, apparently hitherto unrecorded in the literature, are described. They were found in 17 cases among 168 consecutively examined brains. There was no correlation with clinical symptoms, or with general autopsy findings. Their morphology and relationship to neighboring structures suggest that they represent a form of physical trauma to the corpus callosum, but the exact mechanism of their production is not clear.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00691309
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  • 10
    Digitale Medien
    Digitale Medien
    Entry of labeled monocytic cells into the central nervous system (1968)
    Springer
    Acta neuropathologica 10 (1968), S. 359-362 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Monocytic cells of CNS ; Radioisotope labelling ; Blood cells entry into the CNS
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Der Eintritt zirkulierender Blutzellen in das Gehirn wurde mittels radioaktiv markierter Zellen aus dem Knochenmark von Spender-auf Empfängertiere untersucht. Die Zellen wurden in vitro oder in vivo mittles H3-Thymidin oder H3-Uridin markiert. Die markierten Zellen vom Charakter der Monocyten oder Makrophagen dringen nach den erhobenen Befunden in normales Hirngewebe ein und sammeln sich in verschiedenartigen Hirnläsionen an. Es ergaben sich Hinweise dafür, daß diese Zellen später in die Milz zurückkehren.
    Notizen: Summary The entry of circulating blood cells into the brain was studied by injecting radioactively labeled cells from the bone marrow of donor animals into recipient animals. The cells were labeledin vitro orin vivo, using H3 thymidine or H3 uridine. Labeled cells having features of monocytes or macrophages were shown to enter normal brain tissue and to aggregate at various types of brain lesions. There was indication that these cells later returned to the spleen.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00690711
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