Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1975-1979  (7)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 55 (1977), S. 711-712 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 57 (1979), S. 965-966 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nuclear medicine 1 (1976), S. 125-136 
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To assess the validity of the quantitative 201Tl scintimetry in various diseases of the heart (coronary heart disease with and without myocardial infarction, non-coronary cardiomyopathy, scleroderma heart disease and asymmetric septal hypertrophy with IHSS), the 201Tl myocardial uptake values for five standardized projections (a) were correlated with the grade of LAD stenosis, (b) the pattern of myocardial wall motion and (c) were compared with the 201Tl uptake values derived from normal patients. Significant reduction (c) of 201Tl myocardial uptake could in individual cases be evaluated in acute myocardial infarction (95%), in dys-and akinesia (90%), in hypokinesia (71%), in scleroderma heart disease (50%), in non-coronary cardiomyopathy (50%) as well as in normokinesia (28%) when associated with LAD stenosis. The mean values (b) of 201Tl uptake in normo-and hypokinesia significantly differed between these two groups and from those evaluated in dys-and akinesia. The latter group showed the lowest 201Tl uptake values computed which in some cases were very close to the mean mediastinal 201Tl uptake. The correlation (a) of individual 201Tl values demonstrated that 201Tl distribution in the myocardium is not only equivalent to myocardial “perfusion” but is corresponding with the myocardial function. In non-coronary cardiomyopathy reduced 201Tl values sometimes could not be separated from values in coronary heart disease (and myocardial infarction). A regional increase of myocardial mass as in septal hypertrophy correlated well with an augmented 201Tl uptake when referred to the 201Tl storage in the mediastinum.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nuclear medicine 3 (1978), S. 71-80 
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study was performed to comparatively assess the diagnostic accuracy of computerized tomography (CT) and nuclear liver-scanning in detecting and defining circumscript and diffuse liver diseases in 83 patients. Presence or absence of liver diseases was assessed based on the results of invasive diagnostic procedures such as biopsy, laparoscopy, laparotomy, and/or autopsy. The percentage of true negative diagnoses was 94% for CT and 91% for static gamma-imaging (n=33). With a rate of 94% true positive diagnoses, CT proved to be superior to gamma imaging with radiocolloids (81% true positives) in diagnosing circumscript liver diseases (n=31). In addition, CT was superior to nuclear imaging regarding discrimination of number and size of space-occupying lesions within the liver. In contrast to nuclear screening, CT scans were pathognomonic to some circumscript liver diseases such as cysts, metastates, and perhaps echinococciasis. This was also true for obstructive jaundice. Nuclear imaging, because it reflects a sort of liver function, was superior with cirrhosis, whereas CT showed only alterations in the size and shape of the liver and spleen.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract After subtraction of the 201Tl background radioactivity which was obtained from the paracardiac region, left ventricular (LV)-201Tl net uptake at rest correlated with (1) the LV-muscle mass and therefore with (2) the LV-oxygen consumption. In normal LV, after maximum coronary dilation with dipyridamole, LV-201Tl net uptake increased little more than LV-oxygen consumption but by factor of 2.27 less than was coronary vascular reserve. In coronary heart disease (c.h.d.), dipyridamole caused a significantly smaller increase of LV-201Tl uptake (factor 1.16) than in normal LV myocardium (factor 1.76). This correlated well with the severity of the disease. Therefore, in maximum coronary dilation passive transport mechanisms may be responsible for augmented uptake and changed LV distribution of 201Tl which depends on the perfusion pattern. In exercise, the 201Tl-background radioactivity decreased from 54% (at rest) to 35% in normal patients and to 44% in c.h.d. Stressed thigh muscles accumulated 201Tl 4.72-fold more than at rest. Therefore, it is still questionable if the myocardium during exercise receives enough 201Tl to be labelled maximum. Since the LV-201Tl count rates in c.h.d., measured over the maximum uptake area were increased to the same amount as in normal myocardium neither in coronary dilation nor during exercise, the validity of using the maximum LV-201Tl uptake as a reference for the minimum one under these conditions is problematic.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Hämodynamische und ventrikeldynamische Determinanten der myokardialen201Thalliumspeicherung wurden an 42 Katzen untersucht. 1. Die ventrikuläre Muskelmasse ist eine der wesentlichen Determinanten der myokardialen Thalliumspeicherung. Dabei speichern die Innenschichten 10 bis 15% mehr als die Außenschichten, während der rechte Ventrikel um 40% weniger Thallium aufnimmt als der linke Ventrikel. 2. Ein Anstieg der Koronardurchblutung und Myokardperfusion durch Dipyridamol führt bei vergleichbarer Muskelmasse zu einer beträchtlichen Zunahme der myokardialen Thalliumspeicherung (um 106%). 3. Eine über die Änderung der Kontraktilität verursachte Änderung des myokardialen Sauerstoffverbauchs führt zu erheblichen Änderungen der myokardialen Thalliumspeicherung, die mit Inotropiezunahme ansteigt und unter negativ inotropen Eingriffen abnimmt. Die Ergebnisse zeigen, daß Ventrikelmasse, Myokardperfusion und myokardialer Sauerstoffverbrauch zu den wesentlichen Determinanten der myokardialen Thalliumspeicherung zu rechnen sind. Durch die quantitative Bestimmung der myokardialen201Thalliumaufnahme ist somit ein brauchbares Äquivalent zur Beurteilung der durch Masse, Fluß und Metabolismus determinierten funktionellen Muskelmasse des Ventrikels gegeben.
    Notes: Summary Studies were performed in 42 cats in order to analyze the determinants of myocardial201Thallium uptake. (1) Ventricular mass represents the major determinant of myocardial201Thallium uptake. The inner (subendocardial) layer of the left ventricle storages 10–15 per cent more Thallium than the outer (subepicardial) layer, whereas the right ventricle has201Thallium accumulation by 40 per cent less than the left ventricle. (2) Coronary perfusion increase as induced by the intravenous injection of dipyridamole leads — at constant muscle mass — to considerable increase in myocardial201Thallium uptake by 106 per cent. (3) Changes in myocardial oxygen consumption as induced by inotropic interventions are associated with considerable changes in the myocardial201Thallium uptake. These results demonstrate that ventricular mass, myocardial flow and myocardial oxygen consumption are major determinants of myocardial201Thallium uptake. Thus, by quantitiative determination of the myocardial201Thallium uptake, a useful equivalent of the viability degree of the left ventricle, which itself is determined by mass, flow and metabolism, may be obtained.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Basic research in cardiology 73 (1978), S. 365-379 
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An insgesamt 158 Patienten wurden die im Rahmen diagnostischer Herzkatheterisierungen, Ventrikulographien und Koronarangiographien ermittelten Parameter mit der quantitativen Thalliumspeicherung des Myokards korreliert: 1. Die Thalliumaufnahme war beim normalen und hypertrophierten menschlichen Herzen linear mit der linksventrikulären Muskelmasse korreliert. 2. Die Korrelation zwischen der linksventrikulären Muskelmasse und der201Thallium-Aufnahme wurde durch Änderungen der Myokardperfusion und des myokardialen Sauerstoffverbrauches beeinflußt. 3. Inotrope Eingriffe wie auch koronardilatierende Pharmaka (Dipyridamol) führten zu einer erheblichen und vergleichbaren Zunahme der myokardialen201Thallium-Aufnahme. 4. Mit zunehmendem Grad der regionalen Wandkontraktionsstörung bei koronarer Herzkrankheit (Hypokinesie, Akinesie, Dyskinesie) erfolgte eine progrediente Abnahme der quantitativen myokardialen201Thallium-Speicherung. 5. Bei linksventrikulärer Hypertrophie ohne koronare Herzkrankheit kann das Ausmaß der201Thallium-Speicherung als Parameter zur Abschätzung des Ausmaßes der linksventrikulären Hypertrophie angesehen werden. 6. Die niedrigsten quantitativ ermittelten201Thallium-Speicherwerte ergaben sich bei Akinesien und Dyskinesien im Rahmen einer koronaren Herzkrankheit sowie beim akuten Myokardinfarkt. Es wird geschlossen, daß die myokardiale201Thallium-Speicherung multifaktoriell determiniert wird. Zu den wesentlichen Determinanten gehören die linksventrikuläre Muskelmasse, die Myokardperfusion und der myokardiale Sauerstoffverbrauch. Die quantitative201Thallium-Szintigraphie ist geeignet, zur Diagnostik und Differentialdiagnostik von regionalen Wandkontraktionsstörungen, Hypertrophien des Herzens und Änderungen der Myokardperfusion und/oder des myokardialen Sauerstoffverbrauches beizutragen.
    Notes: Summary Studies were carried out in order to determine the factors influencing myocardial201Thallium uptake in man. A total of 158 patients was examined with regard to both201Thallium uptake and the assessment of left ventricular and coronary function (e.g. quantitative ventriculography, coronary arteriography, coronary blood flow measurements). The results demonstrate: (1) The201Thallium uptake in the normal and hypertrophied human heart is linearly correlated with muscle mass of the left ventricle. (2) The basic correlation between the201Thallium uptake and the left ventricular muscle mass is influenced by alterations in both myocardial blood flow and myocardial oxygen consumption. (3) Inotropic interventions as well as coronary dilatation dipyridamole) may considerably augment the201Thallium uptake in accordance with changes in myocardial oxygen consumption and/or in myocardial flow. (4) In disorders with regional wall motion abnormalities (hypokinesis, akinesis, dyskinesis) a progressive decrease in the quantitative201Thallium uptake of the left ventricle occurs with increase in the degree of wall motion abnormality. (5) The determination of the quantitative201Thallium uptake of the heart enables the evaluation of hypertrophy degree, of regional wall motion abnormalities and of perfusion changes of the myocardium due to primary coronary dilatation and/or metabolically induces flow alteration. It is concluded that the myocardial201Thallium uptake is determined by multiple factors. The major determinants have been shown to include (i) muscle mass, (ii) myocardial flow, (iii) myocardial oxygen consumption With this regard the clinical data obtained from patient groups with normal ventricular function, with coronary artery disease, with left ventricular wall motion abnormalities and with different degree of left ventricular hypertrophy are correlated with quantitated myocardial201Thallium uptake.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...