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  • 1
    Electronic Resource
    Electronic Resource
    78. Fragestellungen und Ergebnisse prospektiver Studien in der Chirurgie (1978)
    Springer
    Langenbeck's archives of surgery 347 (1978), S. 449-456 
    Details
    ISSN: 1435-2451
    Keywords: Prospective trial ; Surgery, results of ; Prospektive Studie ; Ergebnisse in der Chirurgie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit der Erstbeschreibung einer prospektiven klinischen Untersuchung durch J. Lind (1753) ist die kontrollierte Studie zum wichtigen Gegenstand klinischer Forschung geworden. Gegenstände von prospektiven Studien können sein : prophylaktische Maßnahmen zur Verhütung von Komplikationen (z. B. Thrombose, Streßulcus, Hepatitis, Wundinfektion), Operationsindikation, Operationsvorbehandlung, Operationstaktik und -technik sowie die Nachbehandlung. Für jede Fragestellung werden Beispiele angeführt.
    Notes: Summary Since the first clinical prospective trial of J. Lind in 1753, the controlled study has proved to be an essential instrument in clinical research. Possible topics include: pharmacologic prophylaxis of complications such as stress ulcer, thrombosis, etc., indications for operation, preoperative preparation, choice of surgical procedure, and techniques or postoperative treatment. Examples for each topic are given.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01579375
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  • 2
    Electronic Resource
    Electronic Resource
    Experimentelle Untersuchungen zum Einfluß der Pyloroplastik und der Pylorusstenose auf die motorische und sekretorische Magenfunktion bei der selektiv-proximalen Vagotomie (1979)
    Springer
    Langenbeck's archives of surgery 348 (1979), S. 243-260 
    Details
    ISSN: 1435-2451
    Keywords: Selective proximal vagotomy ; Pyloric stenosis ; Pyloroplastic ; Gastric emptying ; Acid secretion ; Serum gastrin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit einer modifizierten intestinalen Perfusion- und Aspirationsmethode wurden simultan die motorischen and sekretorischen Magenfunktionen nach Gabe einer flüssigen Testnahrung beim wachen Miniaturschwein nach experimenteller Pylorusstenose, alleiniger SPV, SPV mit zusätzlicher Pylorusstenose und SPV mit zusätzlicher Pyloroplastik untersucht. Nach alleiniger SPV fand sich eine initial betonte Abnahme des intragastralen Volumens und eine normale Entleerung in das Duodenum. Bei einer zusätzlichen Pylorusstenose trat keine signifikante Änderung ein. Eine Pyloroplastik führte zu einer signifikanten Anhebung des intragastralen Volumens mit verzögerter Entleerung. Die durch eine SPV reduzierte postprandiale Säuresekretionsleistung wurde weder durch eine Pyloroplastik, noch durch eine Pylorusstenose signifikant verändert. Das basale Serumgastrin war sowohl nach SPV als auch nach SPV in Kombination mit einer Pylorusstenose oder Pyloroplastik erhöht. Nach Nahrungsstimulation kam es zu einem verzögerten Anstieg des Serumgastrins nach SPV, der sich lediglich in der ersten Stunde von den Werten nach SPV mit Pylorusstenose oder Pyloroplastik unterschied. Die vorliegenden Ergebnisse lassen erkennen, daß bei einer SPV durch eine zusätzliche Pyloroplastik keine weitere Verbesserung der sekretorischen und motorischen Funktionen erzielt wird. Weiterhin lassen die erhobenen Untersuchungen den Schluß zu, daß nach SPV mit einer zusätzlichen experimentellen Pylorusstenose keine Entleerungsverzögerung des Magens auftritt und die postoperative Säuresekretion und das Serumgastrin nicht negativ beeinflußt werden.
    Notes: Summary In conscious fullgrown minipigs simple SPV alone, SPV and pyloric stenosis and SPV and pyloroplasty were performed. After a liquid test meal the motoric and secretory function of the stomach were examined simultaneously by a modified method of intestinal perfusion and aspiration. After simple SPV initially a marked decrease of gastric volume and normal emptying into the duodenum were found. With additional pyloric stenosis no significant change was found. The pyloroplasty lead to an increase of gastric volume and delayed emptying. The acid secretion after feeding reduced by SPV was not changed significantly neither by pyloroplasty nor by pyloric stenosis. The baseline values of serum gastrin were elevated after SPV as well as after SPV in combination with pyloric stenosis or pyloroplasty. After food stimulation there was a delayed increase of gastrin after SPV which differed from that after SPV with pyloric stenosis or pyloroplasty only during the first hour. These results show that after SPV no further improvement of the motoric and secretory function can be achieved by an additional pyloroplasty. Furthermore these findings permit the conclusion that even after SPV with additional artificial pyloric stenosis no delayed gastric emptying occurs and that there is no negative effect postoperatively on the acid secretion and gastrin production.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01317611
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  • 3
    Electronic Resource
    Electronic Resource
    Decrease in motor activity — an early symptom in the course of experimental allergic encephalomyelitis (EAE) (1979)
    Springer
    Cellular and molecular life sciences 35 (1979), S. 1207-1208 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Motor activity has been followed in rats during an experimental allergic encephalomyelitis (EAE). The disease was produced by transfer of lymph node cells from sensitized syngenic donors. Small and large movements were permanently registered by an electric activity meter. It could be demonstrated that a decrease of the motility is an early symptome of the disease. Therefore the measurement of the motoric activity might be a useful parameter in the classification of EAE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01963293
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  • 4
    Electronic Resource
    Electronic Resource
    Technique of continuous collection of parotid saliva in the rat (1978)
    Springer
    Research in experimental medicine 172 (1978), S. 247-253 
    Details
    ISSN: 1433-8580
    Keywords: Rat ; Parotid saliva
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A method is described, which is suitable to collect continuously and quantitatively saliva from both parotid glands in rats under in vivo conditions and which allows to investigate salivary electrolyte composition in relation to flow rate during several hours. This might be of expanding scientific interest in disturbances of transepithelial electrolyte transport in various pathophysiological situations (for instance different forms of experimental hypertension, endstage renal failure and so on).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01855835
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  • 5
    Electronic Resource
    Electronic Resource
    Decreased cAMP content of the hypothalamus of genetically hypertensive rats (1978)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 302 (1978), S. 341-343 
    Details
    ISSN: 1432-1912
    Keywords: Cyclic AMP ; Hypothalamus ; Genetically hypertensive rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In genetically hypertensive rats an altered catecholamine content of hypothalamic structures has been reported. In the present study cAMP was estimated in the hypothalamus and cortex of genetically hypertensive rats and compared with normotensive controls of the same strain. It is shown, that the cAMP content of the hypothalamus of the hypertensive animals was decreased to about 60% of control values, whereas there was no difference of the cAMP content in the cortical regions of the same animals. These results indicate an alteration of the adenyl cyclase-cAMP-phosphodiesterase system in hypothalamic structures of genetically hypertensive rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00508306
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  • 6
    Electronic Resource
    Electronic Resource
    Model for the low magnetic moment of Ba2Zn2Fe12O22 (Zn2Y) (1977)
    Springer
    Applied physics 14 (1977), S. 325-326 
    Details
    ISSN: 1432-0630
    Keywords: 75.30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The experimental value of the spontaneous magnetic moment μ(0) at OK of Zn2Y is 8% lower than the theoretical one. This reduction of the moment is ascribed to a local spin reversal on octahedral 3b-sites due to a high Zn-concentration in the S-block.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00882739
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  • 7
    Electronic Resource
    Electronic Resource
    Photoredoxreaktionen an Mono-oxalato-bisphenanthrolin-kobalt(III)-Komplexen im festen Zustand (1976)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 422 (1976), S. 65-74 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: On Light Induced Redox Reactions of Mono-oxalate-bis(phenanthroline) Cobalt(III) Complexes in Solid StatePhoto redox reactions on complexes of the type [Co(phen)2ox]X · n H2O (phen = 1,10 phenanthroline, ox = C2O4-; X- = F, Cl, Rr, I, HCOO, C3H7COO, ClO4; n = 1-3) are discussed. They are initiated from irradiations in the 350 nm region. Thin layers of the compounds and KBr pellets of the complexes were photolyzed and quantum yield values were determined by IR-spectroscopic or analytical determination of concentration. Quantum yield values were found to be dependent on different anions X in the second coordination sphere. The brutto reactions mere characterized analytically and by spectroscopic methods and magnetic measurements. The products of photolysis were identified. A mechanism of light induced reactions is proposed on base of stoichiometry of the reactions and of identification of oxalate anion radicals by EPR.
    Notes: Es wird über Photoredoxreaktionen an Komplexen des Typs [Co(phen)2ox]X · nH2O (phen = 1,10-Phenanthrolin, ox = C2O4-; X- = F, Cl, Br, J, HCOO, C3H7COO, ClO4; n = 1-3) im festen Zustand berichtet, die durch Einstrahlung bei 350 nm ausgelöst werden. Durch Photolyse an dünnen Schichten und in KBr-Preßlingen wurden die Quantenausbeuten der Photoredoxreaktionen über naßanalytische bzw. IR-spektroskopische Konzentrationsermittlung in Abhängigkeit von unterschiedlichen Anionen X ermittelt. Der Bruttoumsatz der Photolysereaktionen wurde analytisch, mittels spektroskopischer Methoden sowie magnetochemisch bestimmt und die Endprodukte wurden identifiziert. Auf Grund der Stöchiometrie der Reaktion und dem EPR-spektroskopischen Nachweis von Oxalatanionradikalen wird ein Mechanismus für den Ablauf der Reaktion vorgeschlagen.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19764220109
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  • 8
    Electronic Resource
    Electronic Resource
    Über den Einfluß nichtkoordinierter Anionen auf das thermische Verhalten von Mono-oxalato-bis-phenanthrolin-kobalt(III)-Komplexen (1976)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 425 (1976), S. 81-90 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: The Influence of Non-coordinated Anions on Thermal Behaviour of Mono-oxalato-bis-phenanthroline-cobalt (III) ComplexesThe thermal redox reactions of coordination compounds from type [Co(phen)2ox]X · nH2O (phen = 1.10-phenanthroline; ox = oxalate; X- = F, CI, Br, J, HSO4, SCN, OCN, NO3, CIO4, RCOO; n = 1-4) were studied by thermomagnetic, thermogravimetric and DSC methods. The results show dependence of the thermal stability of these mixed-ligand complexes on various anions X in the second coordination sphere. From results of thermal composition the complexes investigated can be ordered in view of their different thermal stability. The stoichiometry for several complexes has been examined on basis of their gaseous and solid products and reasons for anion depending behaviours are discussed.
    Notes: Thermoinduzierte Redoxreaktionen von Komplexverbindungen des Typs [Co(phen)2ox]X · nH2O (phen = 1.10-Phenanthrolin; ox = Oxalat; X-=F, Cl, Br, J, HSO4, H2PO4, SCN, OCN, NO3, CIO4, RCOO; n = 1 bis 4) wurden thermomagnetisch, thermogravimetrisch sowie mittels DSC-Messungen untersucht. Der Ablauf der Thermoredoxreaktionen dieser Komplexe im festen Zustand wird wesentlich vom Anion X in der zweiten Koordinationssphäre bestimmt. Entsprechend der unterschiedlichen Wirksamkeit der Anionen können die Komplexverbindungen hinsichtlich ihrer thermischen Stabilität geordnet werden. Auf Grund spektroskopischer und elementar-analytischer Untersuchungen der Thermolyseprodukte können die Bruttoreaktionsgleichungen der Thermoredoxreaktionen formuliert und mögliche Ursachen für das anionenabhängige Verhalten diskutiert werden.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19764250110
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  • 9
    Electronic Resource
    Electronic Resource
    Zur Konstitution von Bis-(phenanthrolin)-kobalt(II)-Komplexen (1975)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 412 (1975), S. 141-147 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: On Bis(phenanthroline) cobalt(II) ComplexesSpectrophotometric investigations of [Co(phen)2X2] complexes in the IR and UV/VIS region are described. The results of this investigations show cis octahedral arrangement of the ligands. From the v1- and v3-transitions of the electronic spectra the LF parameters B and Dq are calculated and from this the two electron transition v2 is estimated. [Co(phen)2X2] complexes show symmetry equilibria between octahedral and tetrahedral forms in solutions by reason of complex disproportionation reactions. The green form of the chloride complex could be isolated and identificated as [Co(phen)Cl2].
    Notes: IR- und elektronenspektroskopische Untersuchungen an [Co(phen)2X2]-Komplexen (X=F-, Cl-, Br-, J-, NCS-, NCO-, NO3-, SO4--, ClO4-, HCOO-, H3CCOO-, H5C2COO-, n-H7C3COO- und Salicylat) wurden zur weiteren Charakterisierung dieses Koordinationstyps durchgeführt. Die Untersuchungsergebnisse deuten auf cis-oktaedrische Ligandenanordnung in diesen Verbindungen hin. Aus den v1- und v3-Übergängen der Elektronenspektren wurden die Ligandenfeldparameter B und Dq berechnet sowie die Lage des Zweielektronenübergangs v2 bestimmt. Die [Co(phen)2X2]-Verbindungen unterliegen in Lösung Symmetriegleichgewichten zwischen pseudooktaedrischer und -tetraedrischer Ligandenanordnung, die auf Komplexdisproportionierung zurückzuführen ist. Die grüne Form des Chloridkomplexes konnte isoliert und als [Co(phen)Cl2] identifiziert werden.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19754120206
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