Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1970-1974  (19)
  • 1965-1969  (9)
  • 1
    Electronic Resource
    Electronic Resource
    Postsynaptic influences on the vestibular non-deiters nuclei from primary vestibular nerve (1969)
    Springer
    Experimental brain research 8 (1969), S. 190-200 
    Details
    ISSN: 1432-1106
    Keywords: Vestibular ; EPSP ; IPSP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurones in the descending, medial and superior vestibular nuclei of the cats were explored with intracellular microelectrodes. Cerebellar- and spinal-projecting neurones were identified by their antidromic invasion from the region of fastigial nuclei and from the second cervical segment, respectively, and the others by their location. The central actions of the primary vestibular impulses upon these non-Deiters vestibular nuclei neurones were investigated by using electric stimulation of the ipsilateral vestibular nerve. Many of these cells received excitatory postsynaptic potentials (EPSPs) monosynaptically, similar to those evoked in the ventral Deiters neurones, as described elsewhere, except that the unitary EPSPs are often larger. Some cells received only polysynaptic EPSPs or IPSPs and a few cells were not influenced at all.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234539
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Pharmacological properties of the postsynaptic inhibition by Purkinje cell axons and the action of γ-aminobutyric acid on Deiters neurones (1967)
    Springer
    Experimental brain research 4 (1967), S. 43-57 
    Details
    ISSN: 1432-1106
    Keywords: Purkinje cells ; Deiters neurones ; Inhibitory synapses ; GABA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1.Various drugs were applied intravenously or into the fourth ventricle and their effects upon the inhibition exerted by Purkinje cell axons were appraised by both extra- and intracellular recording from Deiters neurones. Strychnine, picrotoxin, pentamethylenetetrazol, β-methyl-β-ethylglutarimide, noradrenaline, dopamine, dibenamine and nethalide did not affect this inhibition. 2.γ-aminobutyric acid (GABA) and inhibitors of GABA transaminase were applied iontophoretically into the vicinity of Deiters neurones through an outer barrel of coaxial electrodes, the effects being observed either intra- or extracellularly through an inner barrel. 3. GABA depressed both inhibitory and excitatory postsynaptic potentials and often blocked the spike potentials, while it increased the membrane conductance. 4. GABA also produced a membrane hyperpolarization of 3–8 mV. Concomitantly both the spike potential and after-depolarization increased in amplitude and the after-hyperpolarization decreased. 5. In a few cases hydroxylamine but not amino-oxyacetic acid potentiated the inhibition, there being an increase in the inhibitory postsynaptic potentials thereby induced. 6. These effects were considered in connection with the possibility that GABA acts as a natural transmitter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00235216
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Synaptic action of the fastigiobulbar impulses upon neurones in the medullary reticular formation and vestibular nuclei (1970)
    Springer
    Experimental brain research 11 (1970), S. 29-47 
    Details
    ISSN: 1432-1106
    Keywords: Fastigial ; Reticular formation ; Vestibular nuclei ; PSP ; Disfacilitation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In anaesthetized cats, the fastigial nucleus of cerebellum was stimulated with electric pulse currents, and the effects thereby induced were investigated by recording intracellularly from cells in the medullary reticular formation, the nucleus of Deiters and the descending vestibular nucleus. The early effect commonly seen in these cells was initiation of excitatory postsynaptic potentials (EPSPs) with monosynaptic latencies from both sides of the fastigial nuclei. These EPSPs appeared to be produced in part by a kind of axon reflex through cerebellar afferent fibres, but a certain portion of them was ascribable to the crossed fastigiobulbar axons, as they were influenced by stimulation of the cerebellar cortex in the manner to be expected from the previous study on cerebellar nuclei. These EPSPs were followed by a sequence of a prolonged disfacilitatory hyperpolarization and a late facilitatory depolarization, which apparently reflected the inhibition and disinhibition, respectively, produced in fastigial neurones via Purkinje cell axons of the corticonuclear projection. Either EPSPs or IPSPs were also induced in both reticular and vestibular neurones through polysynaptic pathways in which the fastigiobulbar projection might have been involved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234200
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The origin of cerebellar-induced inhibition of Deiters neurones II. Temporal correlation between the trans-synaptic activation of Purkinje cells and the inhibition of Deiters neurones (1966)
    Springer
    Experimental brain research 2 (1966), S. 350-364 
    Details
    ISSN: 1432-1106
    Keywords: Deiters neurones ; Inhibition ; Climbing fibre responses ; Inferior olive
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intracellular recording with microelectrodes has been employed to reveal the causal relationship between the trans-synaptic activation of cerebellar Purkinje cells and the postsynaptic inhibition of Deiters neurones. Cerebellar stimulation produced in Deiters neurones not only monosynaptic IPSPs with latency of 0.9–1.5 msec, but also the delayed IPSPs at 1.5–9 msec. Correspondng to the latter, Purkinje cells were found to be activated orthodromically with the characteristic climbing fibre responses (CFRs), the latency varying from 0.8 up to 10 msec. On the other hand, stimulation of the inferior olive first induced EPSPs in Deiters neurones, presumably monosynaptically, then with a short delay of less than a millisecond CRFs in Purkinje cells of the anterior lobe, which in turn were succeeded by IPSPs in Deiters neurones after a further delay of a millisecond. Spinal stimulation activated the inferior olive trans-synaptically and thereby produced CFRs in Purkinje cells and a sequence of EPSPs and IPSPs in Deiters neurones. Close correlation between these spinal-induced events in both neurone species was further indicated by the concurrence of their fluctuations in intensity, these fluctuations being characteristic of the spino-olivary transmission mechanism. These results strongly support the postulate that the cerebellar Purkinje cells are inhibitory in their action upon Deiters neurones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234780
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Electrophysiological analysis of the vestibulospinal reflex pathway of rabbit. II. Synaptic actions upon spinal neurones (1973)
    Springer
    Experimental brain research 17 (1973), S. 497-515 
    Details
    ISSN: 1432-1106
    Keywords: Vestibulospinal ; Cervical ; Thoracic ; PSPs ; Deiters'
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In anaesthetized rabbits, the effects of VIIIth nerve stimulation were studied in the cervicothoracic segments of the spinal cord by recording spike field potentials representing the secondary vestibular volleys, postsynaptic potentials in spinal neurones and corresponding field potentials. It was revealed that an excitatory action was conveyed by the medial vestibulospinal tract (MVST) fibers bilaterally and also by the lateral vestibulospinal tract (LVST) fibers ipsilaterally. Both of these two excitatory fiber groups conducted the secondary vestibular volleys with relatively fast velocities. An inhibitory action was effected bilateraly by those MVST fibers which conducted secondary vestibular volleys with a relatively slow velocity, as previously described in oats. By direct stimulation of the medulla it was demonstrated that both excitatory and inhibitory MVST fibers arise from the middle portion of the vestibular nuclear complex in and around Deiters' nucleus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234864
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Electrophysiological analysis of the vestibulospinal reflex pathway of rabbit. I. Classification of tract cells (1973)
    Springer
    Experimental brain research 17 (1973), S. 477-496 
    Details
    ISSN: 1432-1106
    Keywords: Vestibulospinal ; VIIIth nerve ; Deiters' nucleus ; Rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In anaesthetized rabbits, the medulla was surveyed with recording microelectrodes to identify different types of vestibulospinal tract neurones. Field potentials, unitary extracellular spikes and intracellular potentials were recorded during antidromic stimulation at C1 and C6 segments and during orthodromic stimulation through VIIIth nerve. The lateral and medial vestibulospinal tracts (LVST and MVST) were stimulated discriminately with the method developed in Appendix. On the basis of different axonal courses and conduction velocities, three major groups were distinguished for those cells which were activated monosynaptically by the primary vestibular afferents; 1. fast conducting LVST; 2. fast conducting MVST; and 3. slowly conducting MVST. Three other groups were discriminated for those cells which received only a polysynaptic or no action from primary vestibular afferents. These were; 4. fast conducting LVST; 5. slowly conducting LVST and 6. slowly conducting MVST. All of these six types of VST cells were represented within Deiters' nucleus. Only a relatively small number of MVST cells were found in the medial vestibular nucleus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234863
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Cerebellar control of the vestibulospinal tract cells in rabbit (1973)
    Springer
    Experimental brain research 18 (1973), S. 446-463 
    Details
    ISSN: 1432-1106
    Keywords: Cerebellum ; Vestibular ; Spinocerebellar ; Purkinje ; Deiters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The organization of the cerebellar, vestibular and spinal inputs to the lateral and medial vestibulospinal tract (LVST and MVST) cells was studied in anaesthetized rabbits. Synaptic actions of these inputs were determined by recording postsynaptic potentials intracellularly and also unit spike discharges extracellularly from a number of LVST and MVST cells. As reported previously in cats, inhibition was evoked very frequently from the vermal cortex of the cerebellar anterior lobe and less frequently from that of the posterior lobe. However, no such inhibition was derived from the flocculus. The cerebellar inhibition was exerted upon both LVST and MVST cells, whether they received monosynaptic activation from the primary vestibular afferents (second-order) or not and whether they conducted impulses fast or slowly. However, the inhibition was frequently absent in “slow” “second-order” MVST cells. The vast majority of LVST and MVST cells received an excitatory input from the spinocerebellar afferents ascending the funiculus posterolateralis. This input was particularly prominent from the upper cervical cord. The spinal excitation thus obtained occurred in close connection with the cerebellar inhibition. Hence, it appears that the cerebellar vermis receives the spinal signals that drive LVST and MVST cells and in turn sends out inhibitory signals to adjust the reflex activity in these cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234131
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    The origin of cerebellar-induced inhibition of Deiters neurones I. Monosynaptic initiation of the inhibitory postsynaptic potentials (1966)
    Springer
    Experimental brain research 2 (1966), S. 330-349 
    Details
    ISSN: 1432-1106
    Keywords: Deiters neurones ; IPSP ; Monosynaptic ; Purkinje cells ; Inhibitory neurones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary During stimulation of the anterior lobe of the cerebellum, postsynaptic potentials were recorded intracellularly from ipsilateral Deiters neurones of the cat. In the majority of examined cells, the inhibitory postsynapic potentials were induced with short latency; 1.06 msec on the average from lobule III or IV. The latency was longer (1.23 msec) when the lobule V was stimulated, while it was shorter (0.86 msec) from the juxtafastigial region. It follows that the IPSP was produced via a monosynaptic pathway at a conduction velocity of 15 to 20 m/sec. Recording of the extracellular field potentials and focal stimulation within and around Deiters' nucleus further indicated that the inhibitory impulses propagated out of the cerebellum along a remarkable bundle of fibres which terminated within Deiters' nucleus. These results are all explicable by assuming that the cerebellar Purkinje cells are inhibitory in nature and so produce IPSPs monosynaptically in Deiters neurones via the long corticofugal fibres. Monosynaptic EPSPs were also detected in some Deiters neurones. They are considered to be mediated by the other pathways formed of axon collaterals of the cerebellar afferents.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234779
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Axon reflex activation of Deiters neurones from the cerebellar cortex through collaterals of the cerebellar afferents (1969)
    Springer
    Experimental brain research 8 (1969), S. 249-268 
    Details
    ISSN: 1432-1106
    Keywords: Axon reflex ; Deiters neurones ; Cerebellar afferents ; Cats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary When recording intracellularly from cat's Deiters neurones, stimulation of the anterior lobe of the cerebellar cortex produced excitatory postsynaptic potentials (EPSPs) monosynaptically, in addition to the inhibitory ones (IPSPs) that were identified previously as being produced via Purkinje cell axons. The EPSPs were induced bilaterally from a wide area of the anterior and posterior lobes of the cerebellum, in contrast to the IPSPs that were evoked only ipsilaterally, mainly from the vermal cortex. The latency of the EPSPs was slightly, but significantly, shorter than that of the IPSPs. The presynaptic impulses responsible for these EPSPs were represented by the discrete field potentials and also by unit spikes of individual fibres. The pathway for these EPSPs and presynaptic impulses was pursued by testing their interference, in the manner of impulse collision and refractoriness, with those induced from various spots within or outside the cerebellum. It is found that the excitatory fibres for Deiters neurones extend transversely, and probably longitudinally too, over the culmen and pass out of the cerebellum through cerebellar peduncles. The major portion of them appears to originate from the medulla and a minority from the spinal cord. It is postulated that cerebellar afferents from these structures have synapses with Deiters neurones via their collateral branches, through which a kind of axon reflex occurs to Deiters neurones during stimulation of the cerebellar cortex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234252
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Inhibitory control of intracerebellar nuclei by the Purkinje cell axons (1970)
    Springer
    Experimental brain research 10 (1970), S. 64-80 
    Details
    ISSN: 1432-1106
    Keywords: Intracerebellar nuclei ; Purkinje cells ; Inhibition ; Excitation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In anaesthetized cats, synaptic events in cerebellar nuclei neurones were investigated with intracellular microelectrode techniques. These cells were identified by their antidromic activation along their axons and/or by their location in histological sections. In the cells of lateral nucleus IPSPs were induced monosynaptically during stimulation of the overlying hemispheral cortex of the cerebellum. In the cells of nuclei interpositus and fastigii, similar IPSPs were produced from the paravermal and vermal cortices, respectively. The postulate that the Purkinje cells exert an inhibitory action upon their target neurones thus applies not only to Deiters neurones, as previously proposed, but also to cells in the cerebellar nuclei. Stimulation of the cerebellar afferents at the inferior olive, the pontine nucleus and the lateral reticular nucleus produced EPSPs in cerebellar nuclei cells with relatively brief latencies, probably through axon collaterals of these afferents. The EPSPs were followed by IPSPs and slow depolarizations of disinhibitory nature, which, as studied previously in Deiters neurones, might be caused respectively by activation and subsequent depression of Purkinje cells through the cerebellar intracortical mechanisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00340519
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...