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  • 1970-1974  (10)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 80 (1973), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The levels of serum seromucoid were determined in 16 patients who had severe preeclampsia or eclampsia in their last pregnancy, 6 to 24 months previously. In about one-third of these patients the serum seromucoid levels fell within the normal, non-pregnant range, while in the remaining two-thirds, the serum seromucoid level was above normal. The results suggest that pre-eclampsia or eclampsia could be due to two disease states of different aetiology. Alternatively, the severity of the condition may be related to serum seromucoid level. The immunological implications of the findings are briefly discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 80 (1973), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A group of 12 parous women was investigated following severe pre-eclampsia or eclampsia to see if there was any relationship between serum seromucoid levels, known to be elevated in some of these patients, and cell mediated immune reactions in mixed cultures of their leucocytes and those of their husbands. Statistically significant linear correlations were demonstrated. High levels of maternal serum seromucoid are apparently immunosuppressive in materno-paternal mixed leucocyte reactions. The possible significance of these findings in relation to the aetiology of pre-eclampsia or eclampsia is discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 252 (1974), S. 371-373 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It has been suggested that the circum-Antarctic current first became operative during either the late Oligocene1 about 30 Myr BP, the Middle Oligocene2,3, or the Lower Oligocene4. The first two suggestions were based apparently on interpretations of a late Palaeogene regional unconformity in the ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 227 (1970), S. 384-385 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The controversy was revived by the findings of Madison and co-workers2, who showed that administration of ketone bodies caused increased insulin secretion in dogs; and more recently others have also shown that ketone bodies may cause insulin release from isolated rat pancreas9. In man, however, ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 233 (1971), S. 117-118 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The fossils were recovered from residues obtained by digestion of marble samples in acetic acid. The conodonts include some taxa which are known only from rocks of Pennsylvanian age, that is they are equivalent to Upper Carboniferous in North American terminology. The cono- donts belong chiefly to ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Parasitology research 33 (1970), S. 355-357 
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Parasitology research 35 (1971), S. 173-187 
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The intestine of the infective larva consisted of a solid column of seven cells with no lumen. The cells, which seemed to be enzymatically inactive contained large deposits of glycogen and lipid indicating that the intestine probably functioned as a storage organ at this stage. The development of an intestinal lumen was apparent on the third day of infection when the larva was situated in the host liver. Acid and alkaline phosphatase and leucine amino peptidase activity was detected in the intestine at this stage but feeding had not commenced. Further development of the intestine occurred in the lung stage larva, 8 days after infection, the organ now being fully functional.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Parasitology research 36 (1971), S. 179-192 
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Electron microscope observations of the “excretory” cell of the infective larva reveal that it contains a large nucleus surrounded by cytoplasm containing numerous organelles, multi-granular bodies, vesicles and granules typical of glandular cells. The proximal region of the “excretory” duct bears a number of scattered microvilli, on its adluminal surface, and the distal region is lined with a thin multilayered cuticle. In the liver stage larva 2 days after infection, 2 lateral “excretory” columns are present. These arise from the “excretory” cell body and extend posteriorly for about half the length of the intestine. Each column contains a narrow longitudinal canal surrounded by cytoplasm rich in mitochondria, granular endoplasmic reticulum, free ribosomes and large vacuoles. Evidence was obtained of the passage of substances through the wall of the canal but their chemical nature was not determined. Further extension of the lateral columns is seen in the 8-day, lung-stage larva, the columns now extending for more than two-thirds the length of the intestine. Their diameter is also increased but their internal structure is essentially similar to that of the 2-day liver-stage larva. The “excretory” duct which arises immediately anterior to the nucleus has a structure similar to that of the lateral columns for the first half of its length, the microvilli described in the infective larva being absent at this stage. The distal half of the duct is lined with cuticle.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Parasitology research 37 (1971), S. 255-266 
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Electronmicroscope observations of the pharynx of the 2nd stage infective larva reveal that it is devoid of musculature and is therefore incapable of any pumping activity. By the 8th day when the larva is situated in the host lung however, the radial muscles are well developed and the organ appears to be fully functional. Active secretory glands are present in the pharynx of both the infective and lung stage larvae but those of the latter contain a greater variety of secretory bodies. It is suggested that the pharyngeal glands of the infective larva secrete lytic substances to facilitate host tissue penetration whilst the secretory products of the lung stage larva are concerned with a more diverse range of functions including feeding. No valve like structure was discernable at the pharyngeo-intestinal junction of the larvae recovered from the host lungs 8 days after infection. It is suggested that the cells of the pharyngeo-intestinal junction, function as a shock absorber between the highly mobile pharynx and the relatively static intestine.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A study was made, over a period of 12 weeks, of the distribution of a population of immune-adapted worms that had established themselves in the small intestine of rats as a result of exposure to a number of small daily challenge infections with the nematode Nippostrongylus brasiliensis. Immature adapted worms were found to inhabit a greater length of the small intestine than immature primary infection worms. Mature worms, however, were restricted to the anterior two-fifths of the small intestine, the great majority of these infesting the region of the duodenum. The worms were not expelled from the intestine by an acute host-reaction, a large proportion of the worms still being present on the eighth week after the last larval challenge. Evidence was obtained that these immune-adapted worms favoured the duodenal environment rather than the other regions of the intestine and that this attraction for the duodenum was not affected by the immune state of the host.
    Type of Medium: Electronic Resource
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