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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 3 (1967), S. 111-116 
    ISSN: 1432-1106
    Keywords: Drinking ; Electrical stimulation ; Hypothalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Rats with chronic electrodes in the lateral hypothalamus were induced by electrical stimulation to self-stimulate and drink. The effect of this artificially-elicited drinking on self-stimulation behavior was investigated. Self-stimulation rates at optimal current levels were not changed by induced water intake. However, with the current level just above threshold for self-stimulation the rate was increased significantly when the animals were able to self-stimulate and drink simultaneously. It is suggested that sensory feed-back from the consummatory behavior facilitates the activation of neural circuits in the lateral hypothalamus so that low current stimulation more effectively reinforces self-stimulation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 23 (1967), S. 239-244 
    ISSN: 0001-5520
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 4 (1966), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: The digital computer is used on a routine basis in the ground-water program in Kansas for tasks ranging from the listing of water-quality data in tabular and publishable form to statistically and graphically analyzing a mass of data.In the past year a number of computer programs in FORTRAN IV have been developed by Charles O. Morgan and Jesse M. McNellis using an IBM-7040 computer to store, retrieve, and manipulate water-quality data. These programs:(1) Tabulate data at the rate of 40 chemical analyses of water per minute in a format similar to that found in the Kansas ground-water publications.(2) Perform necessary calculations and print Stiff diagrams at the rate of 30 per minute.(3) Perform necessary calculations and print Piper diagrams, including a square modification of the normally diamond-shaped cation-anion diagram, and trilinear diagrams of the cations and anions. The symbol representing the analyses located on the diagrams can be designated by either an analysis number or a geologic unit number. A cation-anion diagram showing the average chemical composition of water for an aquifer can also be printed. These diagrams for 50 analyses can be produced in 1.5 minutes.(4) Plot maps of 42 individual, combined, or calculated parameters obtained from the data cards. These maps can be plotted to any specified scale and for as many as 10 designated geologic units. Computer time involved for one map with 50 plotted points is 15 seconds.It is estimated that the use of these programs will save several man-months during a ground-water study, and the error inherent in the manual manipulation of data is greatly reduced. The present cost for running 50 analyses through the four water-quality programs on the computer is approximately $20.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Journal of clinical periodontology 31 (2004), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background and Aims: Induction of the pro-fibrotic growth factor TGF-β1 has been suggested as a possible mechanism through which immunosuppressant drugs may induce gingival overgrowth. This study aims to investigate plasma levels of TGF-β1 and relate them to the development and severity of gingival overgrowth in immunosuppressed transplant patients.Materials and Methods: One hundred and thirty-two ciclosporin-treated and 13 tacrolimus-treated transplant patients and 24 drug-free control subjects underwent a full periodontal examination including a determination of the presence and severity of gingival overgrowth.Results: Plasma TGF-β1 concentrations were determined by ELISA, and were found to be significantly elevated in samples from the transplant patients (mean=29.1 ng/ml) as compared with controls (mean=6.1 ng/ml, p〈0.0001). There was no significant difference between the levels of plasma TGF-β1 in the ciclosporin- and tacrolimus-treated patient groups.Conclusions: Furthermore, concomitant treatment with calcium channel blockers did not influence the levels of plasma TGF-β1 in the patients group. The relationship between gingival overgrowth, independent periodontal variables and TGF-β1 plasma concentrations was examined using univariate and multivariate regression analyses; low TGF-β1 plasma concentrations were found to be a risk factor for gingival overgrowth in immunosuppressed patients concomitantly receiving a calcium channel blocker.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 219 (1968), S. 712-713 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. The contour lines are normalized isophotes in the focal region of a 10 cm lens for ruby laser radiation having a parabolic beam profile in the presence of primary spherical aberration. The isophotes are symmetrical about the optic axis. The purpose of this letter is to present results of ...
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 57 (2002), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd
    Grass and forage science 56 (2001), S. 0 
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: An experiment was established in 1991 on a 25-year-old perennial ryegrass/bent (Lolium perenne L./Agrostiscapillaris L.)-dominated pasture in Wales to study the effects of reducing nutrient inputs to previously fertilized upland pasture. The effects of the removal of applications of (1) N (denoted by CaPK) (2) N, P and K (Ca) and (3) N, P, K, and Ca (Nil) were compared with a treatment which received applications of all four nutrients (CaPKN) over a 6-year period (1991–96) in a randomized block design replicated three times. The experiment was managed under a continuous variable stocking regime (ewes and lambs until weaning and ewes thereafter) maintaining a sward surface height of 4·0 cm throughout the grazing season. Although individual liveweight gain of the lambs was unaffected by the treatments, there was a significant reduction (P 〈 0·05) in total lamb liveweight gain, ewe stocking rate and length of grazing season as a result of the withdrawal of nutrients. Over the 6 years total lamb liveweight gain was reduced by 17%, 32% and 45% and ewe stocking rate by 21%, 36% and 49% on treatments CaPK, Ca and Nil, respectively, compared with treatment CaPKN. The effect of withdrawing nutrient inputs on ewe stocking rate was progressive and by 1996 the Nil input treatment displayed a 63% reduction compared with the CaPKN treatment and this was also coupled with a 21-day reduction in length of the grazing season. During the post-weaning period, ewes from the Nil input treatment recorded a liveweight loss in 1995 and only a modest liveweight gain in 1996. This coupled with significantly lower body condition scores (P 〈 0·01) of these ewes in the autumn indicated that the Nil input treatment could lead to reductions in reproductive performance.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 27 (2002), S. 0 
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary This study aimed to examine the attitudes of intensivists and haematologists to the use of blood and blood products using a scenario-based postal questionnaire. One hundred and sixty-two intensivists and 77 haematologists responded to the survey. In four scenarios, the baseline haemoglobin thresholds for red cell transfusion ranged from 6 to 12 g.dl−1. There was significant variation between scenarios (p 〈 0.005). Increasing age, high Acute Physiology and Chronic Health Status II score, surgery, acute respiratory distress syndrome, septic shock and lactic acidosis significantly (p 〈 0.005) modified the transfusion threshold. There were greater variations in the baseline threshold for platelet transfusion. The majority of respondents (72.3%) selected a baseline haemoglobin threshold between 9 and 10 g.dl−1. The thresholds for platelet transfusion were far less consistent.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 57 (2002), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary This prospective observational study was conducted to assess the current transfusion practice in critically ill patients. One thousand two hundred and forty-seven consecutive critically ill patients admitted between February 1999 and October 1999 were included in the study. Overall 666 (53%) patients were administered red cells. Transfused patients had significantly higher intensive care unit␣mortality but also had higher Acute Physiology and Chronic Health Evaluation II scores and longer durations of stay. The average pretransfusion haemoglobin concentration was 〈 9 g.dl−1 in 75% of transfusion episodes. The common indications for transfusion were low haemoglobin (72%) and haemorrhage (25%). Overall, 202 (16%) and 281 (22%) of the patients were transfused platelets and fresh frozen plasma, respectively. The indications for transfusion were haemorrhage, low platelet counts, prolonged prothrombin time or to provide cover for invasive interventions. Most platelet transfusions were given at values in the order of 50–100 × 109.l−1. The pretransfusion platelet count varied according to the indications for transfusion. This study showed that transfusion practice is consistent and that in general there does not seem to be an excessive use of blood components in critically ill patients.
    Type of Medium: Electronic Resource
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