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  • 1
    Electronic Resource
    Electronic Resource
    Bridgehead-bridgehead communication in untransannulated phosphatrane ZP(ECH2CH2)3N systems (1990)
    s.l. : American Chemical Society
    Inorganic chemistry 29 (1990), S. 2214-2220 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00337a008
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  • 2
    Electronic Resource
    Electronic Resource
    Investigation of Ion-Conducting Ormolytes: Structure-Property Relationships (1994)
    s.l. : American Chemical Society
    Chemistry of materials 6 (1994), S. 127-134 
    Details
    ISSN: 1520-5002
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/cm00038a007
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  • 3
    Electronic Resource
    Electronic Resource
    Two portions of the supraspinatus muscle: a new finding about the muscles macroscopy by dissection and magnetic resonance imaging (1994)
    Springer
    Surgical and radiologic anatomy 16 (1994), S. 101-104 
    Details
    ISSN: 1279-8517
    Keywords: Supraspinatus muscle ; Anatomy ; MR imaging ; Fusiform muscle ; Straplike muscle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les coupes axiales d'épaule obtenues en IRM montrent une bande linéaire centrale à l'intérieur du m. supra-épineux, vide, qui ne semble pas représenter uniquement le tendon de ce muscle. En raison de l'importance du m. supraépineux dans les syndrômes douloureux de l'épaule, nous avons étudié l'architecture fibreuse de ce muscle, en comparant 30 imageries par résonnance magnétique nucléaire et 49 dissections cadavériques. Nous avons trouvé que le m. supra-épineux était composé de deux parties distinctes. La longueur moyenne de la partie ventrale est de 88 mm et celle de la partie dorsale de 106 mm. L'angle du tendon central qui est formé par les fibres des deux parties musculaires, fait 50° avec le plan frontal. Les deux parties musculaires agissent probablement différemment dans les mouvements du bras. Ces constatations semblent être importantes pour la physiopathologie des ruptures de la coiffe des rotateurs, qui sont principalement situées en avant, dans la partie ventrale du muscle et dans le tendon central excentrique.
    Notes: Summary Axial MR images of the shoulder joint reveal a central linear band within the supraspinatus muscle void of signal which seems not to represent the only tendon of this muscle. Due to the importance of the supraspinatus muscle for the painful impingement syndrome of the shoulder we studied the fibrous architecture of this muscle comparing 30 MR images and 49 cadaver dissections. We found the supraspinatus muscle to be composed of two distinct portions. The mean length of the ventral portion is 88 mm and of the dorsal portion 106 mm. The angle of the central tendon which is formed by fibers of both muscle portions relative to the frontal plane is 50°. Both muscle portions probably act differently in moving the arm. This finding seems to be important for the pathophysiology of rotator cuff tears which are mainly located anteriorly within the ventral muscle portion and the eccentric central tendon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01627931
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  • 4
    Electronic Resource
    Electronic Resource
    The extravascular contractile system in the human placenta (1994)
    Springer
    Anatomy and embryology 190 (1994), S. 541-548 
    Details
    ISSN: 1432-0568
    Keywords: Human placenta ; Smooth muscle-like cells ; Perivascular contractile sheath ; Nitric oxide synthase type I ; Dipeptidyl peptidase IV
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the human placenta, besides the fetal blood vessel system a second extravascular contractile system exists. It is localized in the chorionic plate and runs in a longitudinal direction and adjacent to fetal blood vessels into the stem villi, where it forms perivascular contractile sheaths. Characteristically, cells of the extravascular contractile system are extremely long and spindle-shaped and give rise to fine cell processes, by which they obviously contact each other or insert into the basement membrane of the trophoblast. They show immunoreactivity with desmin, vimentin, α-actin, myosin, nitric oxide synthase type I (brain form) and dipeptidyl peptidase IV. The ultrastructure suggests that cells of the extravascular contractile system are related to smooth muscle cells, including subpopulations with myofibroblastic features. In stem villi a few cells are nitric oxide synthase type I immunoreactive. These cells are thought to be specialized smooth-muscle-like cells of the extravascular contractile system or cells of the extravascular contractile system related to paraneurons that generate nitric oxide, which, in turn, may modulate the tone of perivascular contractile sheaths. The high dipeptidyl peptidase IV activity suggests that modulation of the extravascular contractile system may also occur by substance P.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190104
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  • 5
    Electronic Resource
    Electronic Resource
    Tierexperimentelle Untersuchungen zur formalen Pathogenese der Rindenkontusionsherde (1964)
    Springer
    Acta neuropathologica 4 (1964), S. 46-57 
    Details
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Cortical contusions were produced by one time percussion-concussion. A blood brain barrier disorder was proved by intra-vital staining with Geigy-blue. Already a few minutes after traumatisation the contusions showed blue colour which regularly could be recognized up to two hours. As shown by the histological studies, the manifestation was independent of the occurrence of haemorrhages characteristic of the early stages of contusion. Therefore it is presumed that functional vascular disturbances play an important role in the genesis of cortical contusions. It is supposed that the cortical contusions represent a morphological intensity-variant of the traumatic cortical lesions.
    Notes: Zusammenfassung Durch Vitalfärbung mit Geigyblau konnte in experimentell durch einmalige Perkussionserschütterung erzeugten Rindenkontusionsherden der Nachweis einer Bluthirnschrankenstörung geführt werden, die sich schon wenige Minuten nach der Gewalteinwirkung durch Blaufärbung des Kontusionsherdes zu erkennen gab und regelmäßig noch 2 Std später feststellbar war. Ihre Manifestation erfolgte, wie sich auf Grund histologischer Kontrolluntersuchungen ergab, unabhängig davon, ob in den Kontusionsherden die für das Frühstadium derselben charakteristischen Hämorrhagien vorhanden waren oder fehlten. Es wird daher nicht nur angenommen, daß funktionelle Durchblutungsstörungen bei der Entstehung der Rindenkontusionsherde die bestimmende Rolle spielen, sondern auch für wahrscheinlich gehalten, daß die Rindenkontusionsherde nur eine morphologische Intensitätsvariante traumatischer Hirnrindenschäden darstellen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687915
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  • 6
    Electronic Resource
    Electronic Resource
    Elektronenmikroskopische Untersuchungen zum Fibrinabbau durch Streptokinase (1964)
    Springer
    Journal of molecular medicine 42 (1964), S. 196-198 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Clots of citrated plasma are produced in vitro by recalcification. Under the influence of small doses of streptokinase, macroscopically is to be seen a significant diminution of these clots. In electron microscopy the superficial stratum of the fibrin clot shows a loss of bands and a partly splitting in direction of the fibril axis. These changes are interpreted as signs of lysis in macromolecular sphere which precedes lysis of the fibrin fibrils in molecular sphere.
    Notes: Zusammenfassung In vitro hergestellte Citratplasmagerinnsel zeigen nach 24stündiger Einwirkung relativ kleiner Dosen von Streptokinase eine makroskopisch zu erkennende deutliche Verkleinerung als Folge einer Teillyse. Im elektronenmikroskopischen Bild sind an den oberflächlichen Fibrinfasern ein Verlust der Querstreifung und teilweise Aufspaltungen in der Längsrichtung der Fasern zu erkennen. Diese Veränderungen werden als Lysevorgänge in der makromolekularen Ordnung angesprochen, die der Auflösung der Fibrinfasern im molekularen Bereich vorausgehen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01482623
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  • 7
    Electronic Resource
    Electronic Resource
    In vitro-Untersuchungen zur Frage der Fibrinolyse und Thrombolyse durch Streptokinase (1963)
    Springer
    Journal of molecular medicine 41 (1963), S. 1010-1014 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Nur in vitro-Versuche mit Zugabe der Streptokinase nach der Gerinnung („äußere Lyse“) sind mit den therapeutischen Verhältnissen bei der Behandlung thromboembolischer Erkrankungen vergleichbar. In Erweiterung früherer Versuche wurden Nativblut- und Citratplasmagerinnsel in vitro extrem hohen Streptokinasedosen ausgesetzt. Während es an den Citratplasmagerinnseln zu einer völligen Lyse kommt, zeigen die Nativblutgerinnsel keinerlei Auflösung. Unter Luftabschluß gebildete Nativblutgerinnsel zeigten unter Streptokinase weder bei Luftzutritt noch bei Luftabschluß während des Lyseversuches eine Lösung. Unter Luftabschluß gebildete Citratblutgerinnsel zeigten auch im Lyseversuch unter Luftabschluß eine deutliche Verkleinerung. Mit dem Präparat Varidase, das neben Streptokinase auch Streptodornase enthält, kommt es zu den gleichen Versuchsergebnissen wie mit Streptokinase allein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01478864
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  • 8
    Electronic Resource
    Electronic Resource
    Zum Mechanismus der Fibrinolyse durch Streptokinase (1963)
    Springer
    Journal of molecular medicine 41 (1963), S. 1200-1203 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Zur Prüfung des Mechanismus der Fibrinolyse werden Gerinnsel aus gleichen Mengen von recalcifiziertem Citratplasma in Röhrchen verschiedener Weite gleichen Streptokinasemengen in physiologischer Kochsalzlösung ausgesetzt. Hierbei ergibt sich, daß die Lysegeschwindigkeit bei gleicher Streptokinasemenge der Berührungsoberfläche des Gerinnsels mit der Streptokinase proportional ist, daß die Lyse von den Gerinnseloberfläche her schichtweise fortschreitet und daß die Gerinnsel nicht von innen nach außen aufgebrochen werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01480264
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  • 9
    Electronic Resource
    Electronic Resource
    Isozymes and general protein patterns as taxonomic markers in the taxon Nephtyidae (Annelida Polychaeta) (1994)
    Springer
    Marine biology 119 (1994), S. 31-38 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Seven Nephtys species and one species of the genus Aglaophamus (collected from different European tidal and subtidal locations between 1989 and 1991) were compared with respect to six isozyme systems (α-amylase, esterase, hexokinase, malate dehydrogenase, malic enzyme, phosphoglucoseisomerase) as well as with respect to general protein patterns with non-specific staining. The proteins were obtained from the tissue (proboscis, individual segments) of single individuals, the species of which had previously been accurately determined, and were separated by isoelectric focusing (IEF) in polyacrylamide gels. The enzymes were identified by their specific catalytic activities, and the general proteins were visualized by silver staining. All the isozymes proved to be monomorphic within each of the various polychaete populations. With a single exception, it was impossible to distinguish geographically separated populations of the same species, because the band patterns were completely consistent within the species. The individual enzymes varied in their suitability for species differentiation. Only with respect to esterase and α-amylase could all species be distinguished; the other enzymes studied were identical in morphologically similar species. In contrast, each species could be identified by its general protein pattern, although some species differed from others in the position of a few bands only. Individuals of N. hombergii, N. caeca and N. cirrosa with abnormally shaped parapodia, as well as juvenile nephtyids, could be unequivocally assigned to their respective species by IEF. Only in the case of N. longosetosa were two morphological variants found to differ in their electrophoretic characteristics; one of them is interpreted as a new species, not previously described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00350103
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  • 10
    Electronic Resource
    Electronic Resource
    Untersuchungen über die Verwendbarkeit von Inulin-131J zur Funktionsdiagnostik der Niere (1964)
    Springer
    Journal of molecular medicine 42 (1964), S. 966-967 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Animal tests with Inulin-131I were carried out for the first time for the purpose of developing a radio-medical method for the investigation of the glomerular function of the kidneys. Distribution studies in rats revealed renal accumulation of 12 or 15%, respectively, after the administration of 3 or 30 mg/kg by intravenous injection. After 4 hours the preparation was excreted completely. The time-activity curves measured above the kidneys in rats and dogs showed the peak 2 min after injection (30 mg/kg) or 5 min after injection (3 mg/kg). According to these findings Inulin-131I can be applied clinically as a renal diagnostic. As according to the prevailing opinion, Inulin-131I is particularly suitable for registering the glomerular function, and Hippuran-131J in addition for that of the tubular function, a sensible combination of both tests should allow better and more differentiated results than the present nephrographic methods.
    Notes: Zusammenfassung Mit dem Ziel, ein nuklearmedizinisches Verfahren zur Untersuchung der glomerulären Funktion der Niere zu entwickeln, wurden erstmals Tierversuche mit Inulin-131J durchgeführt. Verteilungsstudien an Ratten ergaben nach i. v. Injektion von 3 bzw. 30 mg/kg eine renale Akkumulation von 12% bzw. 15% der Eingabe. Nach 4 Std war das Präparat vollständig ausgeschieden. Über den Nieren gemessene Zeit-Aktivitätskurven bei Ratten und Hunden zeigten Gipfel 2 min p.i. (30 mg/kg) bzw. 5 min p.i. (3 mg/kg). Nach diesen Befunden kann Inulin-131J für die Nierendiagnostik klinisch eingesetzt werden. Da — nach der gültigen Auffassung — mit Inulin-131J vorwiegend die glomeruläre, mit Hippuran-131J zusätzlich die tubuläre Funktion erfaßt wird, muß die sinnvolle Kombination beider Teste differenziertere und bessere Aussagen als die bisherigen nephrographischen Methoden gestatten.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01484424
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