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  • 1
    Electronic Resource
    Electronic Resource
    Chemistry of 9-diazoxanthene and 9-xanthylidene (1979)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 101 (1979), S. 3906-3916 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00508a031
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Reinvestigation and reevaluation of addition and insertion reactions of 9-diazoxanthene and 9-xanthylidene (1978)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 100 (1978), S. 2922-2923 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00477a074
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Male and female meiosis in grasshoppers II. Chorthippus brunneus (1975)
    Springer
    Chromosoma 51 (1975), S. 381-389 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The frequencies and distribution patterns of chiasmata in the autosomal bivalents of Chorthippus brunneus are very similar in male and female meiosis. The mean cell chiasma frequency of oocytes is however significantly higher than that of spermatocytes, but this difference is almost certainly due to the incremental effect of the X bivalent on the chiasma frequencies of oocytes. The implications of these findings in terms of chiasma control are briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326324
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Analysis of exchanges in differentially stained meiotic chromosomes of Locusta migratoria after BrdU-substitution and FPG staining (1978)
    Springer
    Chromosoma 69 (1978), S. 163-178 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Differential staining of the sister-chromatids of meiotic chromosomes of Locusta migratoria was achieved following abdominal implantation of BrdU tablets and fluorescent plus Giemsa (FPG) staining of fixed and squashed testicular follicles. This paper presents a detailed analysis of crossover exchanges between light and dark chromatids in monochiasmate bivalents. Approximately half the bivalents studied had visible exchanges of dark and light chromatids associated with the chiasmata, as expected if chiasmata originate by breakage and rejoining exchange events between randomly selected non-sister chromatids. In all the bivalents studied the visible crossover exchanges coincided exactly with chiasmata thus showing that chiasma movement (terminalisation) does not occur subsequent to crossing-over in Locusta migratoria, and that chiasmata are therefore accurate indicators of crossing over. It was noted that a proportion (9.5%) of chiasmata were associated with apparently anomalous exchanges of dark and light chromatids which could not be explained by conventional crossing-over. Various hypotheses for the origin of these anomalous exchanges are considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00329915
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  • 5
    Electronic Resource
    Electronic Resource
    The pharmacokinetics of beta-methyl digoxin compared with digoxin tablets and capsules (1976)
    Springer
    European journal of clinical pharmacology 10 (1976), S. 231-236 
    Details
    ISSN: 1432-1041
    Keywords: Digoxin ; beta-methyl-digoxin ; capsules ; bioavailability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The intestinal absorption and urinary elimination rate of total cardioactive material was compared following digoxin and beta-methyldigoxin (BMD) administration to twelve healthy volunteers. Significantly more injected digoxin was recovered in urine. Urinary clearance was more rapid for digoxin, mean half-lives of elimination being 35 hours for digoxin and 40 hours for BMD. Calculated percentage intestinal absorption was lowest for digoxin tablets with a dissolution rate of 77% in one hour, intermediate for BMD tablets, and maximal for an experimental soft gelatin formulation of digoxin in solution. Respective mean values were 75%, 87% and 97%. Similar steady state plasma concentrations followed twice daily ingestion of the 0.25 mg digoxin tablets and 0.20 mg BMD tablets. Mean peak plasma concentration and percentage urinary recovery of ingested dose were higher during continued BMD administration. Between-subject variation in absorption was higher for the digoxin tablets. The comparative intestinal absorption of BMD and digoxin depends upon the formulation. Digoxin is virtually completely absorbed from a solution encapsulated in soft gelatin. Relatively more BMD is eliminated by nonrenal routes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558334
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  • 6
    Electronic Resource
    Electronic Resource
    Distribution of Radioactive Selenium in Mice (1962)
    [s.l.] : Nature Publishing Group
    Nature 196 (1962), S. 1294-1296 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN the course of experimental studies of the nutritional importance of traces of selenium, the distribution of radioactive selenium within the tissues of mice was investigated. Selenium, tagged with selenium-75, was introduced into lucerne (Medicago sativa L.) by growing the plants in a nutrient ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1961294a0
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    New Physics Building At Queen Mary College, University Of London (1963)
    [s.l.] : Nature Publishing Group
    Nature 197 (1963), S. 1142-1145 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ON January 23, the new building for the Department of Physics at Queen Mary College was formally opened by Sir Harrie Massey, in the presence of nearly 200 senior members of universities, Government and industrial offices and laboratories, local schools and other organizations. Deputizing at short ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1971142a0
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  • 8
    Electronic Resource
    Electronic Resource
    Quantitative Histochemistry of Succinate Dehydrogenase in Tissue Sections (1963)
    [s.l.] : Nature Publishing Group
    Nature 197 (1963), S. 568-570 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ALTHOUGH methods of estimating succinate dehydro-L\. genase quantitatively in tissue sections have been described1-3, such techniques do not appear to have been widely adopted. In these communications tetrazolium salts have been used as electron acceptors, and enzymatic activity has been estimated ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/197568b0
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  • 9
    Electronic Resource
    Electronic Resource
    Multiple Medullæ in Wool Fibres (1962)
    [s.l.] : Nature Publishing Group
    Nature 193 (1962), S. 1001-1001 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1 Fig. 2 A search of the literature has disclosed no previous reports of this feature except the one fibre mentioned by Brown and Onions1. Fig. 1 shows a typical portion of the two medullae, one more frequently interrupted than the other. Photographing of a part containing fragments of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1931001a0
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  • 10
    Electronic Resource
    Electronic Resource
    Tissue Dilution Artefact; a Re-interpretation of Variations in Levels of Succinic Dehydrogenase during Chemical Carcinogenesis (1961)
    [s.l.] : Nature Publishing Group
    Nature 191 (1961), S. 1203-1203 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The histochemical results indicated that the succinic dehydrogenase activity of the liver cells was high in liver from rats fed on a complete diet or on a low-protein methionine-supplemented diet5 with or without DAB, and that in the course of feeding this activity per cell did not alter ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1911203a0
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