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Digitale Medien

Immunochemical identification of an α"1-acid glycoprotein-antigenic determinant on carcinoembryonic antigen (CEA) and non-specific cross-reacting antigen (NCA)

Ochi, Y. ; Ura, Y. ; Hamazu, M. ; [weitere]

Amsterdam : Elsevier

Clinica Chimica Acta 138 (1984), S. 9-19

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ISSN: 0009-8981

Schlagwort(e): Auto-antibody ; Carcinoembryonic antigen (CEA) ; Immune determinant ; Monoclonal antibody ; α"1-Acid glycoprotein

Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Thema: Medizin

Materialart: Digitale Medien

URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(84)90349-8

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Digitale Medien

Plasma 1,25-dihydroxyvitamin D concentrations in cords, newborns, infants, and children (1980)

Seino, Y. ; Shimotsuji, T. ; Yamaoka, K. ; [weitere]

Springer

Calcified tissue international 30 (1980), S. 1-3

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ISSN: 1432-0827

Schlagwort(e): 1,25-(OH)2-D ; Children ; Newborns

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin , Physik

Notizen: Summary Plasma 1,25-dihydroxyvitamin D [1,25-(OH)2-D] was measured in cord serum, newborns, infants, and children. The mean for the values obtained from the six cords was significantly higher than the mean for the older children (6–15 years). The mean for the six newborns (0–1 week) was significantly higher than that for the older children. The mean for the nine infants (1 week-6 months) and the 14 younger children (6 months-6 years) was significantly higher than that for older children. The present study suggests that the perinatal period is associated with a marked increase in 1,25-(OH)2-D.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02408599

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Digitale Medien

Interaction between carbamazepine and bromperidol (1997)

Otani, K. ; Ishida, M. ; Yasui, N. ; [weitere]

Springer

European journal of clinical pharmacology 52 (1997), S. 219-222

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ISSN: 1432-1041

Schlagwort(e): Key words Carbamazepine ; Bromperidol; reduced brom- peridol ; plasma concentration

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Abstract Objective: The interaction between carbamazepine and bromperidol was studied in 13 schizophrenic inpatients. Methods: Before carbamazepine addition, the subjects were taking bromperidol 12–24 mg · day−1 for 1–20 weeks. Carbamazepine 400 mg · day−1 was coadministered for 4 weeks, and blood samplings were performed before carbamazepine addition and at weekly intervals after the addition. Plasma concentrations of bromperidol and its reduced metabolite were measured by high-performance liquid chromatography. Results: Carbamazepine significantly decreased plasma concentrations of both bromperidol and reduced bromperidol for all weeks. On average, the plasma concentrations of bromperidol and reduced bromperidol at 4 weeks were 37% and 23% of the corresponding precarbamazepine values. Despite these decreases in plasma concentration, the Clinical Global Impression scores decreased slightly but significantly after carbamazepine addition. Conclusion: The present study suggests that carbamazepine decreases plasma concentrations of bromperidol and its reduced metabolite by inducing the metabolism of these compounds. Nevertheless, adjunctive carbamazepine may be useful for schizophrenic patients treated with bromperidol.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/s002280050277

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