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  • Adiabatic transformation  (1)
  • Cis-Parinaric acid = fluorescent probe for lipid peroxidation  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Ethanol-Induced Cell Death by Lipid Peroxidation in PC12 Cells (1997)
    Springer
    Neurochemical research 22 (1997), S. 1187-1192 
    Details
    ISSN: 1573-6903
    Keywords: Lipid Peroxidation ; ethanol ; Cis-Parinaric acid = fluorescent probe for lipid peroxidation ; Resveratrol = antioxidant from grapes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Free radical generation is hypothesized to be the cause of alcohol-induced tissue injury. Using fluorescent cis-parinaric acid and TBARS, lipid peroxidation was shown to be increased in the presence of trace amounts of free ferrous ion in PC12 cells. This increase in lipid peroxidation was enhanced by ethanol in a dose dependent manner and also correlated with loss of cell viability, as measured by increased release of lactate dehydrogenase (LDH). Resveratrol, a potent antioxidant, had a protective effect against lipid peroxidation and cell death. These findings strongly suggest that ethanol-induced tissue injury and cell death is a free radical mediated process, and may be important in alcohol-related premature aging and other degenerative diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1021968526696
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A new method for quantum processes in fermionic heat baths (1987)
    Springer
    Journal of statistical physics 49 (1987), S. 811-826 
    Details
    ISSN: 1572-9613
    Keywords: Adiabatic transformation ; fermion bath ; Grassmann algebra ; influence functional ; path integral ; real-time density matrix
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The general path-integral formalism for real-time dynamics for a quantum system in a fermionic environment proposed previously is investigated by using a new method called local adiabatic transformation. This method is based on the observation that in the long-time limit (the time scale of the system is much larger than that of the environment, typically characterized by the inverse of the cutoff frequency of the environment), most degrees of freedom of the environment will follow the dynamics adiabatically. This feature is utilized by transforming the original problem of coordinate coupling into a problem of velocity coupling. This is achieved by making some simple unitary transformation on the fermion field (before path-integrating out of that field). By doing perturbations on the new problem, all the previous important results are recovered. Further-more, generalizations to more realistic situations [for example, a particle traveling over a large distance and coupled to a Fermi gas through the phase factor exp(ik·R) (the coupling may involve many channels of angular momentum)] are considered and significant results obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01009357
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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