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  • 1
    ISSN: 1432-1440
    Keywords: Adriamycin ; Lungentumoren ; in vivo- in vitro Korrelation ; Adriamycin ; Lung carcinoma ; In vivo-in vitro correlation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The effect of 1.38×10−5 M adriamycin on tritiated uridine incorporation was studied after 3 hours treatment of suspensions of 25 advanced human lung carcinomas in vitro. The results were correlated with the responses to clinical therapy. All tumours which showed an inhibition of uridine incorporation in vitro of more than 40% were also sensitive to clinical treatment with adriamycin.
    Notes: Zusammenfassung Es wurde die Wirkung von 1,38×10−5 molar Adriamycin auf den 3H-Uridineinbau an Zellsuspensionen von 25 menschlichen Lungentumoren untersucht und mit dem Therapie-Erfolg in der Klinik in Beziehung gesetzt. Alle Tumoren mit einer Uridineinbauhemmung in vitro von mehr als 40% waren auch in der Klinik auf eine Behandlung mit Adriamycin sensibel.
    Type of Medium: Electronic Resource
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