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  • 1
    Electronic Resource
    Electronic Resource
    Contractile response to neuropeptide Y of rat isolated duodenum
    Amsterdam : Elsevier
    Peptides 14 (1993), S. 601-605 
    Details
    ISSN: 0196-9781
    Keywords: Cholinergic transmission ; Neuropeptide Y ; Neuropeptide Y(13-36) ; Prostaglandin biosynthesis ; Purinergic transmission ; Rat duodenum ; Smooth muscle
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0196-9781(93)90151-6
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Methanogenic granular sludge formation in an upflow anaerobic sludge blanket reactir treating synthetic methanolic waste (1995)
    Springer
    World journal of microbiology and biotechnology 11 (1995), S. 631-637 
    Details
    ISSN: 1573-0972
    Keywords: Anaerobic treatment ; granular sludge characteristics ; granulation ; methanolic waste ; UASB reactor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A laboratory upflow anaerobic sludge blanket reactor, seeded with fine, suspended, bacterial floc with 1.76 g volatile suspended solids/l, was used to treat synthetic methanolic waste. After 180 days of continuous peration, granular sludge with discrete granules of 1 to 2 mm diam. was formed, with 52 g volatile suspended solids/l. Granules were brown, relatively soft and had a settling velocity of 1.61 cm/s. Extracellular polymeric matter extracted from the granular sludge had high carbohydrate content but low nucleic acid content. The ash of the granular sludge contained Na+, K+ and Mg2+ up to 15.0, 11.7 and 3.75 mg/g, respectively. Scanning and transmission electron microscopy revealed that the granular sludge was dominated by methanogens resembling Methanosarcina.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00361005
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The different mechanisms of action of nicorandil and adenosine triphosphate on potassium channels of circular smooth muscle of the guinea-pig small intestine (1985)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 331 (1985), S. 96-103 
    Details
    ISSN: 1432-1912
    Keywords: Smooth muscle ; ATP ; Nicorandil ; K-channels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nicorandil (10 μmol/l–0.3 mmol/l) and ATP (1 μmol/l–0.1 mmol/l) hyperpolarized the membrane of circular smooth muscle of the guinea-pig small intestine and increased conductance of the membrane probably to K ions as estimated by the effect on the current-voltage relationship. In the presence of a maximally hyperpolarizing concentration of nicorandil (0.1 mmol/l), ATP produced a further hyperpolarization of 5 mV. The ATP-induced but not the nicorandil-induced hyperpolarization required the presence of Ca in the medium, and the ATP-induced hyperpolarization was blocked by apamin treatment (1 nmol/l) or by MnCl2 (1.3 mmol/l). On the other hand, both hyperpolarization responses were blocked by the local anaesthetics procaine (0.1–1 mmol/l), lidocaine (0.1–1 mmol/l) or cocaine (0.3–1 mmol/l), with different potencies. Field stimulation of smooth muscle of the small intestine produced inhibitory junction potentials (i.j.p.s) and these were inhibited by apamin (10 nmol/l–100 nmol/l). In the presence of ATP, the amplitude of the i.j.p.s was markedly reduced, but in the presence of nicorandil the amplitude was only slightly reduced, consistent with the same increase in ionic conductance and hyperpolarization of the membrane. These results indicate that ATP and nicorandil hyperpolarize the membrane by activating different K-channels, i.e. Ca dependent and Ca insensitive K channels, respectively. As assessed from the effects of local anaesthetics and the membrane properties, the circular muscle may also possess other K channels different from the ATP and nicorandil sensitive K channels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00498857
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    Paper (German National Licenses)
    Fulltext
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