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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 56 (1978), S. 351-354 
    ISSN: 1432-1440
    Keywords: Angiocardiography ; Left ventricle ; Premature ventricular contractions ; Coronary heart disease ; Videometry ; Angiokardiographie ; Linker Ventrikel ; Extrasystolen ; Koronare Herzkrankheit ; Videometrie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Kontrastmitteldarstellung des linken Ventrikels im Rahmen der Herzkatheteruntersuchung hat große Bedeutung in der Beurteilung der Dynamik des Myokards und der Herzklappen. Die Injektion von Kontrastmittel in den linken Ventrikel führt häufig zum Auftreten von Extrasystolen. Eine quantitative Analyse des Kontraktionsablaufs ist in diesen Fällen nicht möglich. Dieser Nachteil der Methode wird umgangen, wenn das Kontrastmittel in den rechten Vorhof injiziert wird. Die nach der Lungenpassage erzielte Darstellung des linken Ventrikels ist bei Anwendung der beschriebenen Technik frei von Extrasystolen und erfüllt die Kriterien der quantitativen Ventrikulographie. Die Erfahrungen der Arbeitsgruppe beruhen auf 57 Kontrastmitteldarstellungen des linken Ventrikels bei 32 Patienten mit verschiedenen Herzerkrankungen. Technik, Indikationen und spezielle Anwendungsmöglichkeiten (Videometrie, Druck/Volumen-Beziehung) werden dargestellt.
    Notes: Summary Left ventricular angiography as a diagnostic means is of considerable importance in the evaluation of myocardial and valvular dynamics. The injection of contrast medium into the left ventricle often causes premature ventricular contractions. In these cases quantitative analysis of the contraction pattern is impossible. This can be avoided by injection of the contrast medium into the right atrium. The technique described allows to obtain ventriculograms which meet the criteria for quantitative angiocardiography. 57 ventriculograms have been performed in 32 patients with various cardiac abnormalities. The study describes the technical procedure, the indications and limitations. Furthermore special applications are discussed (videometry, pressure-volume relationship).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 23 (1977), S. 259-269 
    ISSN: 1432-0827
    Keywords: Amorphous calcium phosphate ; Apatite ; Calcification ; Octacalcium phosphate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The maturation of calcium phosphate crystals formed by the conversion of spontaneously precipitated amorphous calcium phosphate (ACP) was studied in aqueous media at temperatures ranging from 20° to 37°. Reaction pH was kept at 7.4 with either Hepes buffer or by the pH-stat addition of base. Reaction kinetics were followed by monitoring solution calcium and total phosphate, and, in the pH-stat controlled reaction, by recording the amount of KOH needed to maintain pH. Reaction products were examined chemically and by X-ray diffraction and transmission electron microcopy. The first crystals to form deviated markedly from apatite in morphology, composition, structure, and solubility. They were extremely thin and flaky in appearance, had a low Ca/P molar ratio (1.4), contained an appreciable amount of acid phosphate (16%), and had an exceptionally largea-axis (10.5 Å vs. 9.4 Å for apatite). With maturation, the crystals became thicker but smaller in lateral dimensions, more apatitelike in structure and composition, and less soluble. However, this ripening of the crystals was accompanied by unusual inflections in the solution Ca and total PO4 curves, and, in the case of the pH-stat experiments, in the OH consumption profiles as well. These anomalous post-ACP solution changes suggest that a phase change had taken place during crystal maturation. Although the observed structural and compositional changes are not inconsistent with the perfection of an initially defective apatite, the changes in crystal morphology and the anomalous behavior of the reaction solution may more accurately reflect a conversion of the ACP first into an OCP-like crystalline phase which subsequently hydrolyzes into apatite.
    Type of Medium: Electronic Resource
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