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  • 1
    Electronic Resource
    Electronic Resource
    Apoptosis in the normal olfactory epithelium of the adult guinea pig (1996)
    Springer
    European archives of oto-rhino-laryngology and head & neck 253 (1996), S. 371-373 
    Details
    ISSN: 1434-4726
    Keywords: Olfactory epithelium ; Apoptosis ; Nucleic acid labeling ; Guinea pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Among nerve cells of vertebrates, the olfactory epithelia are uncommon in their capacity for cell turnover. Apoptosis is well known to play a key role in maintaining homeostasis in continuously renewing tissues. We examined whether true apoptosis occurred in the normal olfactory epithelia of healthy adult guinea pigs using nucleic acid labeling. Subsequently, apoptosis was recognized in olfactory nerve cells, indicating that apoptosis might play a role in turnover of the olfactory epithelium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00178295
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cell death caused by the acute effects of aminoglycoside and zinc in the ampullary cristae of guinea pigs (1997)
    Springer
    European archives of oto-rhino-laryngology and head & neck 254 (1997), S. 153-157 
    Details
    ISSN: 1434-4726
    Keywords: Apoptosis ; Labyrinthine vestibule ; Aminoglycoside toxicity ; Zinc toxicity ; Nick-end labeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We reported that apoptosis occurred in the guinea pig vestibular hair cells after chronic aminoglycoside treatments. In the present study, we used in situ nick-end labeling to determine whether apoptosis was also induced by the acute effects of aminoglycosides in guinea pig ampullar cristae. In addition, we evaluated the effect of zinc supplements upon these ototoxic treatments. After a local application of streptomycin directly to the round window, we found labeled bodies in the vestibular hair cells. The zinc supplement increased the number of labeled bodies resulting in severe hair cell loss. These findings indicate that the acute effects of aminoglycosides also induce apoptosis of the vestibular hair cells, and that zinc enhances aminoglycoside ototoxicity. Consequently, we propose that an interaction with ion channels may play a key mechanism in the processes of apoptosis affecting the vestibular hair cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02471281
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The competition between fusion-fission and deeply inelastic reactions in the medium mass systems (1996)
    Springer
    The European physical journal 353 (1996), S. 387-396 
    Details
    ISSN: 1434-601X
    Keywords: 25.70.−z ; 25.70.Lm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The competition between fusion-fission and deeply inelastic reactions in the Cl + Ni system has been studied by investigating the exit channelQ-value dependence of theZ-distributions of fission-like fragments. TheZ-, kinetic energy- and angular distributions of the fission-like fragments produced in the37Cl +64Ni system atE lab=170, 186 MeV and in the28Si +74Ge system atE lab=176 MeV have been measured by counter telescopes. TheZ-distribution of the37Cl +64Ni system was found to be essentially the same as that of the35Cl +62Ni system at the same bombarding energy. It is shown that this result can not be explained by the statistical fusion fission model but is consistent with a deeply inelastic model. A systematic study of the fission-like phenomenon in this mass region indicates that the maximum angular momenta for fusion reactions as well as the minimum angular momenta for DIC can be reproduced by the Bass model in the sliding limit (f=1.0) while the maximum angular momenta for fully energy-damped deeply inelastic reactions are governed by the strong interaction radius as predicted by the successive critical distance fusion model. The significance of these results are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01285150
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  • 4
    Electronic Resource
    Electronic Resource
    Energy damping feature in light heavy-ion reactions (1989)
    Springer
    The European physical journal 333 (1989), S. 379-388 
    Details
    ISSN: 1434-601X
    Keywords: 25.70.Lm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The energy damped reaction products from37Cl+12C,27Al,48Ti and16O+48Ti were measured over a wide range of angles (typically 18°〈θ lab〈70°), incident energies (160 〈E lab(37Cl)〈200 MeV,E lab(16O)=118 MeV) and charges Z, including two systems (37Cl+37Al and16O+48Ti) which lead to the same compound nucleus64Zn with the same excitation energy and comparable angular momenta. The angular dependences of total kinetic energy (TKE) and dσ/dθ were decomposed into two components (forward peaked and nearly constant at backward angles), and the elemental TKE and cross sections were derived. The backward components of37Cl+27Al and16O+48Ti exhibit very different Z-distributions, indicating that the fragments do not originate from compound nucleus decay. The results can be understood in terms of an energy damping process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01299691
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    Paper (German National Licenses)
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