ISSN:
1432-0428
Keywords:
Cyclosporin A
;
B cell changes
;
pancreatic insulin content
;
insulin levels
;
hyperglycaemia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Cyclosporin A (50 mg/kg orally for 7 days) produced severe degranulation and hydropic degeneration of islet B cells in rats. These changes were accompanied by hyperglycaemia and hypoinsulinaemia, while the pancreatic insulin content decreased by 75%.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00304861
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