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Digitale Medien

A high concentration of Merkel cells in the bulge prior to the attachment of the arrector pili muscle and the formation of the perifollicular nerve plexus in human fetal skin (1993)

Narisawa, Y. ; Hashimoto, K. ; Nakamura, Y. ; [weitere]

Springer

Archives of dermatological research 285 (1993), S. 261-268

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ISSN: 1432-069X

Schlagwort(e): Merkel cell ; Bulge ; Arrector pili muscle ; Nerve plexus ; Skin development

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract The distribution of Merkel cells in human fetal hair follicles was studied using whole mounts of separated epidermis with attached hair follicles. The technique had the advantage of enabling the elucidation of the spatial relationships of Merkel cells with other cells in the skin. In a 16-week-old fetus the hair anlagen had formed one or two epithelial swellings of variable size. In a 17-week-old fetus sebaceous glands and the bulge of the hair follicle were recognizable and immunoreactive Merkel cells were present in the bulge and surrounding the acrotrichium (intraepidermal follicular canal). In a 20-week-old fetus the sebaceous gland and bulge were well formed and immunoreactive Merkel cells were concentrated in the bulge and infundibulum. In vertical sections of a 20-week-old fetus immunoreactive Merkel cells were also situated in the vicinity of the bulge. Arrector pili muscles were first observable in a 24-week-old fetus being weakly stained with anti-desmin antibody. In a 24-week-old fetus, nerves were also stained within the arrector pili muscles with S-100 protein antibody. In the presumptive arrector pili muscle immunoreactivity for S-100 protein developed before or at the same time as immunoreactivity for desmin. Merkel cells or their products in the bulge may serve as attractants for the growing arrector pili muscle which contain peripheral nerves. Following our report that dermal Merkel cells influence the formation of the dermal nerve plexus, perifollicular Merkel cells near the bulge may also play an inductive and growth-stimulative role for the perifollicular nerve plexus.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00371594

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Digitale Medien

The viscoelasticity of spinnable solutions of alkyltrimethylammonium salicylates (1992)

Hashimoto, K. ; Imae, T. ; Nakazawa, K.

Springer

Colloid & polymer science 270 (1992), S. 249-258

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ISSN: 1435-1536

Schlagwort(e): Viscoelasticity ; spinnability ; tetradecyltrimethylammoniumsalicylate ; hexadecyltrimethylammoniumsalicylate ; rodlikemicelle

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Maschinenbau

Notizen: Abstract The viscoelasticity has been measured for aqueous solutions of tetradecyl-and hexadecyltrimethylammonium salicylates (C14TASal, C16TASal). The aqueous solutions of C14TASal without salt displayed the gel-like behavior at 10.0×10−2 g cm−3, but those more dilute than 3.2×10−2 g cm−3 presented the viscoelasticity similar to that of a Maxwell liquid. The Maxwell-like behavior was converted to the polymer-like one on the addition of (0.1–0.2) M NaBr or (0.02–0.2) M NaSal. The gel-like viscoelasticity can be connected with the spinnability of “cohesive fracture failure”, and the Maxwell-like and polymer-like viscoelasticities are concerned with the spinnability of “ductile failure”. The gel-like and Maxwell-like viscoelasticities originate in the pseudo-network formed by the pseudo-linkages between rodlike micelles, while the polymer-like viscoelasticity is caused by the entanglement of long rodlike micelles in semidilute and concentrated solutions. The aqueous solutions of C16TASal behaved very similar to those of C14TASal.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00655477

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Digitale Medien

The spinnability of viscoelastic solutions of tetradecyl- and hexadecyl-trimethylammonium salicylates (1990)

Imae, T. ; Hashimoto, K. ; Ikeda, S.

Springer

Colloid & polymer science 268 (1990), S. 460-468

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ISSN: 1435-1536

Schlagwort(e): Spinnability ; viscoelasticsurfactantsolution ; tetradecyltrimethylammoniumsalicylate ; hexadecyltrimethylammonium salicylate ; rodlikemicelle

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Maschinenbau

Notizen: Abstract The spinnability was measured for aqueous viscoelastic solutions of tetradecyl- and hexadecyltrimethylammonium salicylates (C14TASal, C16TASal) in the absence and presence of sodium salicylate (NaSal) and sodium bromide (NaBr). The spinnability is classified into two types, D and C. While the intrinsic drawing length in type D is proportional to the drawing velocity, the drawing intrinsic length in type C decreases with the drawing velocity or is independent of it. The spinnability changes from type D to C, as the drawing velocity and the surfactant concentration increase, and the temperature lowers. The effect of salt is different between NaSal and NaBr. It can be assumed that a pseudo-network structure composed of rod-like micelles is formed in viscoelastic and spinnable surfactant solutions. Then, the spinnability depends on the balance between the elasticity and the viscosity in which the structure results.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01411005

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Digitale Medien

Polymorphism of coagulation factor XIII B subunit: Further occurrence of FXIIIB*15 in Japanese and phenotyping in bloodstains (1992)

Komatsu, N. ; Kido, A. ; Kimura, Y. ; [weitere]

Springer

International journal of legal medicine 104 (1992), S. 317-319

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ISSN: 1437-1596

Schlagwort(e): Polymorphism FXIIIB ; Population genetics ; Bloodstains ; Polymorphismus FXIIIB ; Populationsgenetik ; Blutspuren

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin , Rechtswissenschaft

Beschreibung / Inhaltsverzeichnis: Zusammenfassung Der Polymorphismus des FXIIIB wurde bei 555 unverwandten Japanern mit Hilfe der isoelektrischen Fokussierung und anschließendem Immunoblotting untersucht. Fünf allgemein vorkommende Phänotypen und die seltene Variante FXIIIB 15-3 wurden beobachtet. Die Allel-Frequenzen waren FXIIIB = 0,3063, FXIIIB2 = 0,0162, FXIIIB3 = 0,6766 und FXIIIB15 = 0,0009. Die Bestimmung der Phänotypen war auch an Blutspuren mit folgenden Lagerungsbedingungen möglich: Bei 37°C über einen Zeitraum bis zu 4 Monate, bei Raumtemperatur und bei 4°C länger als 6 Monate. Das FXIIIB-System kann einen neuen, aussagekräftigen genetischen Marker für gerichtsmedizinische Blutspurenuntersuchungen darstellen.

Notizen: Summary The polymorphism of FXIIIB was investigated in 555 unrelated Japanese individuals using isoelectric focusing and immunoblotting. Five common phenotypes and a rare variant type FXIIIB 15-3 were observed. The allele frequencies were FXIIIB*1 = 0.3063, FXIIIB*2 = 0.0162, FXIIIB*3 = 0.6766 and FXIIIB*15 = 0.0009. Phenotyping was also possible from bloodstains stored at 37°C for up to 4 months and from bloodstains stored at room temperature and at 4°C for over 6 months. The FXIIIB system can provide a new powerful genetic marker for the medicolegal grouping of bloodstains.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01369549

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