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  • 1975-1979  (2)
  • Bone scanning, extraosseous uptake  (1)
  • Self-administration  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Extraosseous tumor uptake of 99m Technetium Phosphate Compounds in children with abdominal neuroblastoma (1978)
    Springer
    Pediatric radiology 7 (1978), S. 159-163 
    Details
    ISSN: 1432-1998
    Keywords: Neuroblastoma, diagnosis ; Neuroblastoma, bone scanning ; Bones, radionuclide studies ; Phosphorous compounds, bone scanning ; Bone scanning, extraosseous uptake
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sixteen patients with abdominal neuroblastoma had 99m Technetium Phosphate Compounds (99m TC-PC) bone scans as a preoperative evaluation for metastatic disease. Ten patients (62%) had extraosseous tumor uptake while six patients (38%) did not. There was no difference in the incidence of tumor calcification, tumor necrosis or hydronephrosis in the two groups. However, VMA levels were significantly higher in the group with extraosseous tumor uptake. Various bone seeking radionuclides are compared to 99m TC-PC and possible mechanism for extraosseous uptake of such radionuclides are postulated. Awareness of the frequency of such uptake should reduce the possibility of errors in the interpretation of bone scans in patients with neuroblastoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00975440
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Head-Shake distributions during self-maintained dependence on morphine, methadone, and l-alpha-acetylmethadol (LAAM) in the rat (1977)
    Springer
    Psychopharmacology 54 (1977), S. 105-107 
    Details
    ISSN: 1432-2072
    Keywords: Morphine ; Methadone ; LAAM dependence ; Self-administration ; Head shakes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Adult female Sprague-Dawley rats were prepared with chronic cortical and muscle electrodes and i.v. cannulas, made tolerant to and physically dependent on morphine, and trained to lever press for i.v. morphine self-injections to maintain dependence. Methadone or l-alpha-acetylmethadol (LAAM) was then substituted for morphine in some of these rats. During self-maintained dependence on either morphine or methadone, head shakes appeared and increased in frequency before lever pressing for selfinjections. In contrast, there were fewer head shakes during LAAM dependence, which were evenly distributed over the entire duration of the interinjection interval. These findings suggest a relationship between head-shake distributions, drug-seeking behavior, and the pharmacodynamics of these three narcotics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00426549
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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