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  • C-peptide  (1)
  • Insulin-dependent diabetes  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Diabetologia 18 (1980), S. 289-292 
    ISSN: 1432-0428
    Schlagwort(e): Amniotic fluid ; C-peptide ; insulin ; diabetes ; pregnancy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Glucose, insulin and C-peptide were determined in amniotic fluid from 28 normal and 46 insulin-treated diabetic pregnant women. Glucose, insulin and C-peptide concentrations in amniotic fluid were higher in the diabetics than in the normal subjects. In diabetic women insulin levels did not correlate with birth weight or birth weight adjusted for gestational age, but C-peptide did. C-peptide correlated poorly with insulin (p〈0.05) in diabetics but closely (p〈0.002) in normal subjects. These results suggest that amniotic fluid investigations in insulintreated diabetic women should use C-peptide assays as these seem to reflect more closely the insulin production of the fetus than do insulin assays. There were no differences in amniotic fluid glucose, insulin and C-peptide concentrations where the amniotic fluid lecithin-sphingomyelin ratio indicated fetal pulmonary maturity or immaturity.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Diabetologia 18 (1980), S. 447-452 
    ISSN: 1432-0428
    Schlagwort(e): Haemoglobin A1c ; Insulin-dependent diabetes ; Blood glucose control ; Multiple insulin injections
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Haemoglobin A1c concentrations were measured in 102 insulin-treated diabetic outpatients. Only 19% had Hb A1c levels below three standard deviations above the normal mean value (5.23±0.05%). There were no correlations between Hb A1c levels, random C-peptide immunoreactivity or age. A significant correlation (r = 0.49; p〈 0.001) was, however, observed between HbA1c and random plasma glucose levels. The mean random plasma glucose value was normal (89±18 mg/ 100 ml; 5±1 mmol/l) in the patients on insulin three times a day who had received short acting insulin 160 ±6 min before the sampling. — A significant inverse correlation was found (r = -0.26; p〈0.01) between the number of daily insulin injections and the HbA1c concentration. — These results suggest that the use of multiple daily insulin injections improves diabetic control. It should however be emphasised that the patients receiving multiple insulin injections were younger than those on the single injection regime and had lower plasma insulin antibody titres, different social and psychological status and a shorter duration of the disease.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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