Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Expression of CD69 on T-cells from HIV-1-infected children and adolescents increases with increasing viral load (1999)
    Springer
    European journal of pediatrics 158 (1999), S. 638-644 
    Details
    ISSN: 1432-1076
    Keywords: Key words HIV-1 ; T-cells ; CD69 ; Activation ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We evaluated the use of a whole-blood assay that measures spontaneous and activation-induced CD69 expression on peripheral blood T-cells in vitro for assessment of T-cell function in HIV-1-infected paediatric patients. Heparinized venous blood from 28 HIV-1 positive children and adolescents and 23 healthy controls was incubated for 4 h with or without 5 μg/ml phytohaemagglutinin (PHA). Thereafter, analysis of CD69 expression on CD4+ and CD8+ T-cells was done by flow cytometry; simultaneously we determined CD4+ T-cell counts and plasma HIV-1 viral load. Neither spontaneous nor PHA-induced CD69 expression differed significantly between HIV-1 positive patients and healthy controls. However, T-cells from HIV-1 positive patients with plasma HIV-1 viral load levels above 70 × 103 copies/ml showed a higher spontaneous CD69 expression than T-cells from patients with lower plasma viral load levels in different stages of the disease. Antiretroviral treatment in four patients reduced spontaneous CD69 expression in CD4+ T-cells and PHA-induced CD69 expression in CD4+ and CD8+ T-cells significantly after 8 weeks of therapy. Conclusion Spontaneous and activation-induced expression of the early (activation) antigen CD69 on peripheral blood T-cells does not distinguish HIV-1 positive patients from HIV-1 negative healthy controls and is not correlated with peripheral blood CD4+ T-cell counts. This test may not be a reliable marker for functional T-cell deficiency during early stages of HIV disease. Increased spontaneous as well as PHA-induced CD69 expression on T-cells from HIV-1-infected children and adolescents in vitro may rather reflect HIV-induced pre-activation of T-cells in vivo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310051167
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Behandlung von Besenreisern mit einem blitzlampengepumpten gepulsten Farbstofflaser mit 1,5 ms Impulsdauer (1998)
    Springer
    Der Hautarzt 49 (1998), S. 560-565 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Besenreiser ; Sklerotherapie ; Blitzlampengepumpter gepulster Farbstofflaser ; Selektive Photothermolyse ; Key words Ectatic leg veins ; Sclerotherapy ; Flashlamp-pumped pulsed dye laser ; Selective photothermolysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A new flashlamp-pumped pulsed dye laser with 1,5 ms pulse length and tunable wavelengths between 585 and 600 nm (Candela ScleroPLUS) is now available for the treatment of ectatic leg veins. We evaluated 232 single test treatments using 595 and 600 nm wavelength in 75 test persons. For smaller vessels up to a diameter of 0,5 mm, treatments at 16 and 18 J/cm2 showed good results in 60 and 82% respectively; for vessels up to 1 mm in 27 and 33%. Treatment at 595 nm was a little more effective than at 600 nm. Larger vessels could not be treated effectively. The main side effects consisted in hyper- (34%) or hypopigmentation (30%). Thus, in addition to the usual sclerotherapy, this laser is a useful device for the treatment of leg vein ectasia.
    Notes: Zusammenfassung Zur Behandlung kosmetisch störender Besenreiser steht ein neuer blitzlampengepumpter gepulster Farstofflaser mit 1,5 ms Impulsdauer und verschiedenen Wellenlängen zwischen 585 und 600 nm zur Verfügung (Candela ScleroPLUS). Wir evaluierten 232 einmalige Probebehandlungen mit 595 und 600 nm Wellenlänge bei 75 Probanden. Bei kleineren Gefäßen bis 0,5 mm Durchmesser konnte bei Behandlung mit 16 bzw. 18 J/cm2 unter Zusammenfassung beider Wellenlängen in 60 bzw. 82% der Fälle ein zufriedenstellendes Ergebnis erzielt werden, bei Gefäßen bis 1 mm noch in knapp 27 bzw. 33%, wobei bei 595 nm tendenziell bessere Ergebnisse als bei 600 nm beobachtet werden konnten. Bei größeren Gefäßen zeigte sich kein deutlicher Erfolg. Die Nebenwirkungen beschränkten sich im wesentlichen auf Hyper- (34%) und Hypopigmentierungen (30%). Dieser Laser stellt somit eine sinnvolle Ergänzung zur herkömmlichen Sklerosierungstherapie dar.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050789
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Crystallization kinetics of isotactic polypropylene blended with atactic polystyrene (1990)
    Springer
    Colloid & polymer science 268 (1990), S. 528-535 
    Details
    ISSN: 1435-1536
    Keywords: Polypropylene/polystyreneblends ; nucleation ; isothermalcrystallization ; spheruliticgrowth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Crystallization kinetic parameters, such as spherulitic growth rates, nucleation densities, and Avrami-exponents, have been determined by optical microscopy for isotactic polypropylene blended with atactic polystyrene. It is found that the crystallization of iPP is strongly influenced by the presence of polystyrene. With increasing PS concentration in the blend, the nucleation densities decrease, while the spherulitic growth rates as well as the positions of thermal peaks, measured by DSC, remain independent of sample composition. Due to the formation of interfaces as a consequence of increasing dispersion of polystyrene the nucleation changes from preferentially thermal to athermal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01410294
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Molecular fractionation in isotactic polypropylene during isothermal crystallization (1998)
    Springer
    Colloid & polymer science 276 (1998), S. 747-749 
    Details
    ISSN: 1435-1536
    Keywords: Key words Polypropylene ; nucleation ; isothermal crystallization ; molecular fractionation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The nucleation frequency of isotactic polypropylene shows for certain molecular weight distributions during isothermal crystallization a “stepwise” development of the nuclei as a function of time. The resulting curve can be fitted by a superposition of exponential functions assuming a separate nucleation density for each nucleation step. The multimodal nucleation is discussed as a consequence of molecular fractionation effects during crystallization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050013
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...