ISSN:
1432-0533
Keywords:
Brain Capillaries
;
Brain Cortex
;
Cat Brain
;
Hypovolemia
;
Morphometry
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Histotopochemical and morphometric investigations were used to determine the following average values of capillary parameters in the cat's brain cortex: diameter $$\bar D_i$$ , percentage of the projected area $${{\bar A^0 } \mathord{\left/ {\vphantom {{\bar A^0 } {_{0^{Ai} } }}} \right. \kern-\nulldelimiterspace} {_{0^{Ai} } }}$$ , surface-to-volume ratio $${{\bar S_i } \mathord{\left/ {\vphantom {{\bar S_i } {\bar V_i }}} \right. \kern-\nulldelimiterspace} {\bar V_i }}$$ , free distances between capillary surfaces $$\bar \lambda$$ and length per unit brain volume $$\bar L_{Vi}$$ . These overall average values per stereotaxically defined brain region of 6 control and 6 hypovolemic animals were calculated by a computer. The hypovolemic condition was achieved by reducing the systemic arterial blood pressure to 50 mm Hg. The resulting hypovolemia caused a significantly diminished diameter $$\bar \bar D_i$$ , a highly increased length per unit brain volume $$\bar \bar L_{Vi}$$ and an improved surface-to-volume ratio $${{\bar \bar S_i } \mathord{\left/ {\vphantom {{\bar \bar S_i } {\bar \bar V_i }}} \right. \kern-\nulldelimiterspace} {\bar \bar V_i }}$$ of cortical capillaries. The behaviour of these 5 morphometric parameters during hypovolemic oligemia in the cat's brain cortex leads to the conclusion, that an adapted state of the capillary network may be a response to a reduced blood volume and blood pressure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00684391
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