ISSN:
0002-9106
Schlagwort(e):
Life and Medical Sciences
;
Cell & Developmental Biology
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Medizin
Notizen:
Peritoneal free cells from 86 adult mice of both sexes were studied quantitatively and qualitatively.Peritoneal free cells were examined by use of a Coulter counter and channelyzer. The size-distribution curves of peritoneal free cells thus obtained show three peaks, which were almost constant in position in all the cases examined. Thus, peritoneal free cells can be classified into three major populations according to cell size. The total cell numbers of the three populations, composed of small, medium-sized and large cells are, on the average, 1.60 × 106, 2.47 × 106 and 2.90 × 106 in males and 2.05 × 106, 5.57 × 106 and 3.86 × 106 in females at 65 days of age. The number of medium-sized cells is significantly greater in females than in males.Morphologically, three types of peritoneal cells, which constitute the three populations, can be distinguished cytologically and cytochemically, when examined by light microscopy and scanning and transmission electron microscopy. These type I, II, and III cells correspond closely to the three components in the size distribution curves in cell size.Type I cells are small lymphocytes. Type II cells are medium-sized, round mononuclear cells which are distinguishable from lymphocytes by their ultrastructural characteristics, and they constitute a major population which can be separated from the other two populations. Type III cells are macrophages. In the peripheral cytoplasm, they have a labyrinth of tubules which open on the cell surface. .
Zusätzliches Material:
8 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/aja.1001560104
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