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  • 1
    Electronic Resource
    Electronic Resource
    The DiGeorge syndrome (1988)
    Springer
    European journal of pediatrics 147 (1988), S. 496-502 
    Details
    ISSN: 1432-1076
    Keywords: DiGeorge syndrome ; Thymus ; Thymic aplasia ; Immunoglobulins ; Cellular immunity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study describes clinical signs and symptoms in 16 patients with the DiGeorge syndrome (DGS). Diagnosed on the basis of typical facial stigmata, a broad spectrum of severity is seen with respect to congenital heart disease, hypoparathyroidism and immunologic parameters. A simple index of severity is introduced that clearly differentiates complete forms of the syndrome (cDGS) with poor prognosis from partial forms of the syndrome (pDGS). Of 13 pDGS patients, 12 are still living; 8 underwent corrective heart surgery without infectious complications. Moderate to severe mental retardation is seen in all pDGS patients. Due to the lack of thymus function, immunodeficiency is a result of cDGS, whereas immunoregulatory disturbances (hypergammaglobulinaemia, high titres of specific antibody production) prevail in pDGS patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441974
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  • 2
    Electronic Resource
    Electronic Resource
    The DiGeorge sequence (1989)
    Springer
    European journal of pediatrics 149 (1989), S. 96-103 
    Details
    ISSN: 1432-1076
    Keywords: DiGeorge sequence ; Thymus ; Thymic aplasia ; Immunoglobulins ; Cellular immunity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present immunological in vitro data on a group of 16 patients with the DiGeorge sequence (DGS). Detailed tests gave evidence that the decrease in number and function of mature T-cells is closely correlated with phenotypic expression and represents a wide immunological spectrum ranging from normal function to severe combined immunodeficiency with B-cells. Careful immunological testing in DGS may help to plan therapeutic procedures (i. e. thymic factor therapy or bone marrow transplantation) may also have prognostic significance and help to gain insight into mechanisms operative in disturbances of T-cell regulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01995856
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Computer enumeration and generation of physical trees (1987)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Computational Chemistry 8 (1987), S. 549-554 
    Details
    ISSN: 0192-8651
    Keywords: Computational Chemistry and Molecular Modeling ; Biochemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Computer Science
    Notes: A computer-oriented method for the enumeration and generation of physical trees is presented. Physical trees depict acyclic chemical structures, but the term physical is used to stress the process by which the structures are produced.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcc.540080435
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    On the Enumeration of 2-Factors of Polyhexes (1986)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Computational Chemistry 7 (1986), S. 547-564 
    Details
    ISSN: 0192-8651
    Keywords: Computational Chemistry and Molecular Modeling ; Biochemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Computer Science
    Notes: An algorithm is developed for enumerating all 2-factors of polyhexes. Some properties of 2-factors of polyhexes are discussed.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcc.540070418
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    An algorithm for construction of the molecular distance matrix (1987)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Computational Chemistry 8 (1987), S. 170-173 
    Details
    ISSN: 0192-8651
    Keywords: Computational Chemistry and Molecular Modeling ; Biochemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Computer Science
    Notes: A simple computer-oriented method is presented for constructing the (molecular) distance matrix. The distance matrix considered is the graph-theoretical (topological) distance matrix.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcc.540080209
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    On the enumeration and generation of polyhex hydrocarbons (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Computational Chemistry 11 (1990), S. 223-235 
    Details
    ISSN: 0192-8651
    Keywords: Computational Chemistry and Molecular Modeling ; Biochemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Computer Science
    Notes: A novel efficient computer-oriented approach, based on the DAST (dualist angle-restricted spanning tree) code, is introduced for enumeration and generation of planar polyhex hydrocarbons. It is much faster than other approaches in the literature. The numbers of planar polyhex hydrocarbons with 14 hexagons are reported for the first time.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcc.540110208
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    Paper (German National Licenses)
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