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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 63 (1986), S. 650-654 
    ISSN: 1432-1106
    Keywords: Mouse somatosensory system ; Barrel ; Mystacial vibrissae ; Sensory innervation density ; Brain evolution ; Cortical magnification factor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The whisker-to-barrel pathway of mice (an important component of the animal's somatosensory system) was studied in two experiments. In one, the cortical representation of a row of whiskers was caused to be larger by lesioning a neighbouring row of follicles, while the innervation density remained unchanged. In the second experiment mice, selectively bred for particular whisker and barrel patterns, showed for their supernumerary vibrissal follicles a relatively large cortical representation. On the basis of the second experiment we formulate a possible role of the sensory periphery in brain evolution.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1106
    Keywords: Neuronal plasticity ; Whisker ; Somatosensory system ; Cerebral cortex ; GAD-regulation ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sensory experience during perinatal life and adulthood modifies physiological and anatomical characteristics of the central nervous system. So far, this phenomenon has been studied in situations of complete or partial sensory deprivation. We here report that increased sensory stimulation, during four days, of a number of whisker follicles on the face of the adult mouse results in an increased immunoreactivity of glutamic acid decarboxylase (the biosynthetic enzyme of the inhibitory neurotransmitter GABA) in the somatosensory cortex of the adult mouse. Effects were limited to a column of tissue corresponding to the representation of the stimulated follicles and lasted two days beyond stimulation. These findings suggest that sensory stimulation transiently modifies local cortical processing.
    Type of Medium: Electronic Resource
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