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Diffusion of horseradish peroxidase perfused through the lateral ventricle of the chick telencephalon (1975)

Delorme, Pierre ; Gayet, Jacques ; Grignon, Georges

Springer

Cell & tissue research 157 (1975), S. 535-540

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ISSN: 1432-0878

Keywords: Cerebral perivascular spaces ; Peroxidase ; Electron microscopy

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Horseradish peroxidase, perfused into the lateral ventricle of chick brain, freely and slowly diffuses through the cerebral extracellular spaces. The layer of astrocytic end-feet surrounding blood capillaries does not constitute a barrier to the tracer which permeates the basal lamina, diffuses between the pericytic cells and finally accumulates in the intercellular space beneath the tight junctions between contiguous endothelial cells. No evidence was found for transport by micropinocytotic vesicles from the cerebral parenchyma to the capillary lumen.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00222605

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