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  • 1
    Electronic Resource
    Electronic Resource
    Mononuclear cell infiltrate and HLA-DR expression in low grade astrocytomas (1988)
    Springer
    Acta neuropathologica 76 (1988), S. 281-286 
    Details
    ISSN: 1432-0533
    Keywords: Astrocyte ; Macrophage ; Lymphocyte ; Major histocompatibility complex antigens ; Cellular immunity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Frozen samples from 23 low grade (grade I and II) astrocytomas were studied by means of a panel of monoclonal antibodies to macrophages, lymphocytes (and their subsets) and HLA-DR antigens. Macrophages were present in low to moderate numbers in 38%–86% of cases, the variance in figures depending on the antibody used. T lymphocytes, the majority of CD8 phenotype, were detected in low numbers in 78% of tumours. B lymphocytes were scanty in 22% (5/22) and totally absent in the remaining cases. HLA-DR antigen was expressed by tumour cells in 35% (6/17) of cases. These findings indicate that in some low grade astrocytomas there is a mononuclear cell infiltrate with macrophages and secondarily CD8+lymphocytes playing the major role. The significance of these findings remains speculative at present.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687776
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  • 2
    Electronic Resource
    Electronic Resource
    The mononuclear cell infiltrate compared with survival in high-grade astrocytomas (1989)
    Springer
    Acta neuropathologica 78 (1989), S. 189-193 
    Details
    ISSN: 1432-0533
    Keywords: Astrocytoma ; Macrophage ; Lymphocyte ; Mononuclear cells ; Survival
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Frozen samples from 92 malignant astrocytomas were stained with a panel of monoclonal antibodies directed against macrophages and lymphocytes. A follow-up to death was available on 68 cases which form the basis of this study. Large numbers of macrophages were found in all cases; T lymphocytes, mostly of the CD8 phenotype were also seen in moderate numbers in 70% of cases. CD4-positive cells were present in small numbers in 32% and B cells were seen in only 8% of cases. Analysis of the survival showed no demonstrable correlation between the numbers of macrophages or CD4 lymphocytes and survival. The survival curves for parencymal CD8 infiltration diverged after 9 months suggesting increased survival for those patients without such an infiltration but the difference failed to reach statistical significance (P=0.37). No correlation between lymphocytic cuffing and survival was seen after studying all paraffinembedded material. We conclude that there is no significant statistical correlation between survival and the various types of mononuclear cell infiltrating malignant astrocytomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688208
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  • 3
    Electronic Resource
    Electronic Resource
    Activation energy for urethane-linkage formation. An improved calculation from the differential scanning calorimetry data (1990)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 28 (1990), S. 1579-1592 
    Details
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Differential scanning calorimetry (DSC) has been utilized in several studies on polymerization kinetics, at different heating rates. However, there are several factors affecting the precision of kinetic parameters. In this work, the activation energy of urethane-bond formation between 2,6-tolylene diisocyanate and diethylene glycol is reported, the latter being in excess in order to minimize problems such as thermal transitions and incomplete reaction in the final step. The DSC technique was applied at different heating rates. Both the equal conversion and equal conversion rate options of the method are discussed. The latter appears to be a more adequate option for the system studied here. The results obtained show a good agreement with the model used.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pola.1990.080280623
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  • 4
    Electronic Resource
    Electronic Resource
    Dielectric properties of fluid-saturated bone: a comparison between diaphysis and epiphysis (1988)
    Springer
    Medical & biological engineering & computing 26 (1988), S. 313-316 
    Details
    ISSN: 1741-0444
    Keywords: Bone conductivity ; Bone impedance ; Bone permittivity ; Diaphysis ; Epiphysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02447087
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  • 5
    Electronic Resource
    Electronic Resource
    Variation of the electric properties along the diaphysis of bovine femoral bone (1991)
    Springer
    Medical & biological engineering & computing 29 (1991), S. 441-446 
    Details
    ISSN: 1741-0444
    Keywords: Bone conductivity ; Bone impedance ; Bone permittivity ; Cortical bone ; Femoral diaphysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A preliminary study is presented of the variability of the electric properties, in the axial, tangential and radial directions, as a function of position in the diaphysis of a femoral bovine bone. The measurements were carried out at three frequencies: 100 Hz, 10 kHz and 1 MHz. It is shown that both the conductivity and the permittivity exhibit significant variations along the diaphysis, and increase in magnitude towards the epiphyses. From this study, the variation of the electric properties cannot be clearly and directly ascribed to the longitudinal variability of the total volumetric fluid content of the bone. The results reflect the orthotropic nature of the electric properties, at any given location, and indicate a position-dependent tendency towards axis symmetry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02441667
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  • 6
    Electronic Resource
    Electronic Resource
    Ceramic thin films deposited on Si(100) by laser ablation: Application as buffer layers for YBa2Cu3O7 films (1993)
    New York, NY [u.a.] : Wiley-Blackwell
    Advanced Materials for Optics and Electronics 2 (1993), S. 99-103 
    Details
    ISSN: 1057-9257
    Keywords: Buffer layers ; Laser ablation ; Superconducting films ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Ceramic thin films of yttria-stabilised zirconia (YSZ), SrTiO3(STO) and CeO2 have been deposited on Si(100) substrates by laser ablation. The films have been characterized by X-ray diffractometry, field emission scanning electron microscopy and secondary ion mass spectrometry (SIMS). The effects of the oxygen partial pressure during deposition and the substrate temperature were studied. All the films have preferential orientation: (h00) and (hh0) for STO and (hhh) for CeO2 and YSZ. The films show a low density of particulates and a very smooth surface. SIMS profiles indicate a low interdiffusion between film and silicon. One of the applications of these materials is their use as a buffer layer for the growth of YBCO on silicon. Because both materials are highly reactive, it is necessary to put a barrier between YBCO and silicon. For this purpose we used the ceramic films previously deposited in order to obtain superconducting YBCO films. The deposited YBCO films present good superconducting properties with zero resistance at temperatures between 80 and 85 K.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/amo.860020113
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  • 7
    Electronic Resource
    Electronic Resource
    Determination of the kinetic parameters for the polymerization of a polyurethane using an improved method of differential scanning calorimetry (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 46 (1992), S. 571-580 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The kinetic parameters for the polymerization reactions of two polyurethane systems were determined by using an improved method of differential scanning calorymetry (DSC). The calculated activation energy, reaction order, and Arrhenius prefactor show good correlation with the experimental results. The method used here shows several improvements as respects to other DSC methods: the three kinetic parameters can be calculated directly; it is more accurate than other DSC methods; and it requires only one heating rate, during the calorimetric experiments, to determine the activation energy.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1992.070460402
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  • 8
    Electronic Resource
    Electronic Resource
    Study of crosslinking density in polydimethylsiloxane networks by DSC (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 55 (1995), S. 1317-1327 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A calorimetric study for estimating crosslinking densities of polydimethylsiloxane (PDMS) networks is presented. It involves the experimental determination of the heat capacities of the polymer with (Cip) and without (C0p) crosslinking. The theoretical basis of the method is described as well as the procedure used for the determination of the Cps. The crosslinking densities of PDMS networks, determined by absorbency (swelling) measurments, using the Flory-Rehner equation, and by the method described here, are compared. The PDMS, obtained by the anionic synthesis of octamethylcyclotetrasiloxane, was analyzed by gel permeation chromatography and infrared spectroscopy. Separate samples of the polymer were further crosslinked at different network densities. The Cps and the thermal stabilities were determined by DSC and TGA, respectively. The results indicate that the crosslinking density ratios of the polymer networks calculated by the relation ΔCip/C0p are in reasonable agreement with those obtained from absorbency measurements. The crosslinking density can also be obtained from heat capacity measurments if the density of the network is known at the temperature that ΔCp is obtained. © 1995 John Wiley & Sons, Inc.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1995.070550905
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  • 9
    Electronic Resource
    Electronic Resource
    Assay of cholinesterase using a proenhancer of the luminol-H2O2-horseradish peroxidase reaction (1995)
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 10 (1995), S. 285-289 
    Details
    ISSN: 0884-3996
    Keywords: Cholinesterase ; luminol ; pro-enhancer ; chemiluminescence ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: 2-Naphthyl acetate acts as a pro-enhancer of the luminol-H2O2-horseradish peroxidase reaction. Cholinesterase hydrolyses the bound acetyl group and produces 2-naphthol, and this compound is an enhancer of the chemiluminescent reaction. We studied the kinetics of chemiluminescent emission and the influence of 2-naphthyl acetate and cholinesterase enzyme concentration. The cholinesterase concentration versus chemiluminescence intensity maximum was linear for cholinesterase between 0 and 181 μU/mL, with a detection limit of 8 μU/mL and a relative standard deviation of 9.5% (n = 3), for a sample containing 90.67 μU/mL of cholinesterase.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bio.1170100505
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  • 10
    Electronic Resource
    Electronic Resource
    Enhancement and inhibition of luminol chemiluminescence by phenolic acids (1995)
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 10 (1995), S. 175-184 
    Details
    ISSN: 0884-3996
    Keywords: Luminol ; enhanced chemiluminescence ; phenolic acid ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: We explored the behaviour of a series of phenolic acids used as enhancers or inhibitors of luminol chemiluminescence by three different methods to determine if behaviour was associated with phenolic acid structure and redox character. All the phenolic acids inhibited chemiluminescence when hexacyanoferrate(III) was reacted with the phenolic acids before adding luminol. The redox character of these compounds was clearly related to structure. When hexacyanoferrate(III)-luminol-O2 chemiluminescence was initiated by phenolic acid-luminol mixtures some phenolic acids behaved as enhancers of chemiluminescence, and others as inhibitors. We propose a mechanism to explain these findings. We found direct relationships between the redox character of the phenolic acids and the enhancement or inhibition of the chemiluminescence of the luminol-H2O2-peroxidase system and we propose mechanism to explain these phenomena.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bio.1170100306
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