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  • 1
    ISSN: 1432-0649
    Keywords: 42.60.Kg ; 87.60 Gp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract This paper describes a new application of optical heterodyne detection using a laser beam for two-dimensional imaging of the internal structure of strongly scattering media in which the structure is completely obstructed from normal visual observation. The directional resolution capability for image formation due to the excellent antenna properties of the heterodyne technique is verified experimentally using a ground glass to cause strong scattering of the signal beam. Successful image detection of a test target placed in a highly scattering absorptive medium, with spatial resolution better than 400 μm in the case of our experiments, demonstrates that this Coherent Detection Imaging (CDI) method can overcome the diffuse nature of images in media such as those of biomedical interest and others to achieve scanning and tomographic imaging.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 182 (1983), S. 85-94 
    ISSN: 1433-8580
    Keywords: Protein-bound polysaccharide ; PS-K ; Complement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A protein-bound polysaccharide from mycelia ofCoriolus versicolor PS-K, clinically used as an immunomodulator, has been shown to restore the decreased cellular immune response and to exhibit host-mediated antitumor activity. In this experiment, PS-K was found to increase serum complement level in guinea pig and in human without malignancy, when hemolytic assay of complement was performed using sensitized sheep erythrocytes for the classical pathway activity and unsensitized rabbit erythrocytes for the alternative pathway activity. Assay of complement components revealed increase in C3 level in guinea pig, but no significant changes in Clq, C4, C3, properdin, C3 activator, and C $$\bar 1$$ -inhibitor in human, while C5 and C9 were depressed. Conversion ofβ1C toβ1A was observed in the 7th day's plasma of these patients by crossed immunoelectrophoresis. Biosynthesis of guinea pig C3 was accelerated by administration of PS-K, but that of C4 was not affected. These evidences suggested that PS-K might potentiate immune response of the host by elevating serum complement level, in addition to the activation of the complement system.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1437-160X
    Keywords: Rheumatoid arthritis ; Immune complexes ; Anti-immunoglobulin ; Complement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Circulating immune complexes by fluid phase Clq binding assay, complement components and anti-immunoglobulin levels were studied in sera of 35 patients with rheumatoid arthritis (RA). In 23 of the 35 sera (65.7%), circulating immune complexes were positive, and the mean±SD of Clq binding activity (ClqBA), 44.5±19.4%, was significantly high compared to that of healthy persons, 17.4±8.2%. Antigenic determination of complement components revealed that Clq, C3, C5, C9, factor B and Cl esterase inhibitor (CIINH) were significantly high in sera of RA, but C4 and properdin were not. The disease activity correlated with ClqBA, IgG- and IgM-anti-immunoglobulins, C9 and serum IgG. On the other hand, ClqBA correlated with both IgG- and IgM-anti-immunoglobulin levels but not with complement components.
    Type of Medium: Electronic Resource
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