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  • Articles: DFG German National Licenses  (2)
  • Congenital abnormalities, cervical spine  (1)
  • Immunofluoreszenz-Untersuchungen  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Spinal abnormalities and the atypical form of the Mayer-Rokitansky-Küster-Hauser syndrome (1992)
    Springer
    Skeletal radiology 21 (1992), S. 459-462 
    Details
    ISSN: 1432-2161
    Keywords: Congenital abnormalities, genitourinary system ; Congenital abnormalities, cervical spine ; Laparoscopy ; Radiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In 96 patients with congenital absence of the uterus and upper vagina, the Mayer-Rokitansky-KüsterHauser (MRKH) syndrome, it proved possible to distinguish between the typical and the atypical form using laparoscopy. The typical form was characterized by symmetrical nonfunctioning muscular buds (the Müllerian duct remnants) and normal fallopian tubes, and the atypical form by aplasia of one or both buds, one bud smaller than the contralateral one, with or without dysplasia of one or both fallopian tubes. The atypical form was found in 52 patients (54.2%). Radiographs of the spine showed that congenital spinal abnormalities, especially the Klippel-Feil (KF) syndrome, were seen in 14 of the 52 patients with the atypical form only. Renal agenesis or ectopia together with the MRKH and KF syndromes, known as the MURCS association (MU: Müllerian duct aplasia; R: renal agenesis/ectopia; CS: cervical somite dysplasia), was diagnosed in 10/52 patients in the atypical group. From our results we conclude that additional cervical spine films in patients with the MRKH syndrome are indicated only in the atypical form the syndrome. In those cases where the MRKH syndrome is associated with the KF syndrome, the MURCS association should be considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190992
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunopathology of psoriasis (1979)
    Springer
    Archives of dermatological research 264 (1979), S. 65-71 
    Details
    ISSN: 1432-069X
    Keywords: Stratum corneum antibodies ; Immunofluorescence studies ; Polymorphonuclear leukocytes ; Proteases ; Stratum corneum-Antikörper ; Immunofluoreszenz-Untersuchungen ; Polymorphonukleare Leukozyten ; Proteinase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Untersuchungen der psoriatischen Hautveränderungen mittels der direkten und indirekten Immunofluorescenzmethode zeigen in der Hornschicht Immunoglobulin- und Komplementablagerungen auf. Das IF-Muster ist dasselbe wie bei der Bindung der im normalen Serum auftretenden anti-Stratum corneum-Antikörper an dem spezifischen Substrat, d.h. normaler Hornschicht. Die Bildung von Immunkomplexen zusammengesetzt von anti-Stratum corneum-Antikörpern scheint das Phänomen der «Squirting papilla» zu verursachen, wobei das normalerweise nicht zugängliche Stratum corneum unter der Einwirkung von Traumen oder Leukocyten-Proteinasen antigenisch wird. Die Proteinase-Produktion durch angeregte polymorphonukleare Leukocyten ist vermutlich ein wichtiger pathogenetischer Faktor in Psoriasis, wobei das Stratum corneum das Target ihrer Einwirkung ist und reaktiv (antigenisch) wird, was die in vivo-Fixation der Stratum corneum-Antikörper ermöglicht.
    Notes: Summary Immunofluorescence (IF) studies by the direct and indirect methods demonstrate immunoglobulins and complement bound in vivo in psoriatic scales. The IF pattern is comparable to that of stratum corneum antibodies (SCAb) bound in vitro on specific substrate, as visualized by the indirect IF method. Formation of immune complexes can be responsible for the “squirting papilla” phenomenon, and conversion of the stratum corneum — which is normally an inaccessible antigen — into its reactive form seems to be brought about by proteases of polymorphonuclear leukocytes. Stimulation of protease production by polymorphonuclears appears to be an important factor in the pathogenesis of psoriasis. The stratum corneum of the epidermis is probably the target, and becomes an antigen for SCAb present in the circulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00417280
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    Paper (German National Licenses)
    Fulltext
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