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  • 1
    Electronic Resource
    Electronic Resource
    First clinical experiences with hormone-therapy of pachydermia laryngis (1978)
    Springer
    European archives of oto-rhino-laryngology and head & neck 221 (1978), S. 221-225 
    Details
    ISSN: 1434-4726
    Keywords: Larynx ; Pachydermie ; Hormonbehandlung ; Antiandrogene ; Cyproteronazetat ; Larynx ; Pachydermia laryngis ; Hormonetherapy ; Antiandrogens ; Cyproterone-acetate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary First clinical experiences with the anti-androgenic drug cyproteroneacetate in treatment of pachydermia laryngis are reported in eleven male and female patients. This endocrine therapy led to complete healing in four and to marked improvement in six patients. One did not respond. Evaluation of the endocrine state of these patients showed imbalance in the androgen/estrogen equilibrium. As the larynx constitutes a secondary sex characteristic and an endocrine target organ, the significance of endocrine factors for pathogenesis and therapy of epithelial changes on the vocal cords is discussed.
    Notes: Zusammenfassung Es wird über erste klinische Erfahrungen in der Behandlung der Pachydermia laryngis mit dem Testosteronantagonisten Cyproteronazetat an elf Patienten beiderlei Geschlechts berichtet. Diese neuartige Therapie führte in vier Fällen zu vollständiger Heilung, bei sechs Patienten zu wesentlicher Besserung und blieb in einem Fall erfolglos! Hormonbestimmungen deckten Störungen im Androgen/Östrogen-Gleichgewicht auf. Die Bedeutung endokriner Faktoren für die Pathogenese und die Therapie von Epithelveränderungen im Larynx als einem sekundären Geschlechtsmerkmal wird diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01886299
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Anti-androgen-therapy in pachydermia of the female larynx — a new therapeutic possibility (1977)
    Springer
    European archives of oto-rhino-laryngology and head & neck 215 (1977), S. 75-79 
    Details
    ISSN: 1434-4726
    Keywords: Larynx ; Pachydermia laryngis ; Anti-androgens ; Cyproteroneacetate ; Larynx ; Pachydermie ; Anti-Androgene ; Cyproteronazetat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über eine 56jährige Patientin mit Pachydermia laryngis und Hirsutismus berichtet, die erfolgreich mit dem Testosteron-Antagonisten Cyproteronacetat behandelt werden konnte. An Hand dieses Falles wird die Bedeutung androgener Hormone für die Genese von Epithelveränderungen am weiblichen Kehlkopf unterstrichen und die Anwendung antiandrogener Substanzen als neuartige therapeutische Möglichkeit diskutiert.
    Notes: Summary Case-report about a 56 year old white female patient with pachydermia laryngis and hirsutism, successfully treated with cyproterone-acetate, a testosterone antagonist. The significance of androgenic hormones for the development of epithelial changes in the female larynx is emphasized. The administration of antiandrogenic substances as a new therapeutic measure is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00463194
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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